Protein Alignment Afti and Aftph

DIOPT Version :10

• Sequence 1: NP_001356916.1
• Gene: Afti / 41744
• FlyBaseID: FBgn0038223
• Length: 1161
• Species: Drosophila melanogaster
• Sequence 2: XP_006251594.1
• Gene: Aftph / 305544
• RGDID: 1311920
• Length: 932
• Species: Rattus norvegicus
• Alignment Length: 975
• Identity: 205/975 - (21%)
• Similarity: 296/975 - (30%)
• Gaps: 369/975 - (37%)

  Fly    10 STPPPIDFGEEDDDSGLQSTIHLDEGDEYSDFGLVS---------------SSKEPPPPPD---P 56
            |:|||:|.|.||||.        ||..|:..|..||               .|||...|.:   |
  Rat    11 SSPPPLDNGAEDDDE--------DEFGEFGGFSEVSPSGVGFVDFDTPDYTRSKEDFVPSNHFMP 67

  Fly    57 VEEFREKPPDLLEDKQTVEAFNYQVKQKMDYDVFEETAPPTPPPLSLELDDEEL----EEHVPSL 117
            ::|:.|....|...|        .::...|.|:..|.  |||   |....|..|    :..|||.
  Rat    68 IDEYSENVDSLTSLK--------SIQNGKDKDITAEL--PTP---SKGQSDVVLSATSKAMVPSK 119

  Fly   118 KLDSLSLYSTESVSAASTLSPVAETSAVAP---PAMQTTKAHILSHQVTLEDVSDDSDEECSPKK 179
            .||: .|...||:...........::...|   ||...|..:|: ||.|       ..|.|:.:|
  Rat   120 ALDT-PLCGRESLGGVDKGVMQGPSTGQLPSFSPADFRTDTNIV-HQTT-------QLESCNGEK 175

  Fly   180 PKELFI------------REGAVDFFAI-------------------EVLATPTLPYG------- 206
            |..|.:            .:|..|..::                   |..|:|...:.
  Rat   176 PACLEVLTNGFAGVETANPQGTEDLDSVADSKGSRPLSTSCGTECILESAASPATEFADFSTFSQ 240

  Fly   207 ----------------------EGFSEEN-----------------VDTG--------------- 217
                                  :|.|:.:                 .|||
  Rat   241 TERTQLEELECAVVNDGDALTIQGNSKSHRVKELNCMKEVTLGGSFADTGDTEREHQVCVSDFHA 305

  Fly   218 ---KGEYVE----NTSQPEESFR--------SLEAQEESSNTLE----KPMEN------------ 251
               :|..||    .|.|.:|...        ||....|:|..:.    |..||
  Rat   306 IADRGLSVEKQDLQTLQQDEFLNSRIQSEAWSLVDSNENSEAIRRERCKTEENDFFVAKCADLSM 370

  Fly   252 ----------------QSRGLSNP--PN---QEES--PHQWGEPANSDTYS------FTNLD--- 284
                            ::|.|:||  ||   .|||  ........|.|:::      .||.|
  Rat   371 DSIKTSDVNEIGSSKEENRKLTNPKSPNPDPTEESVLDDSAASMKNGDSFNGFVTCHDTNEDDFG 435

  Fly   285 -------ATP------KDLVHKEIVPEMQE-----QEDDDDFGDFADFSAAEPQLEITENSTSAF 331
                   .||      :|.:......:..|     .|..||||:|.|.:|.....|:....:...
  Rat   436 DFGTASGTTPPFVTSTQDSMSDVTFEDSSEHFLHFSEPGDDFGEFEDTNAISCPEEMIFTESDLR 500

  Fly   332 ETPSLAINSRTESQPLEVKT-APSTEESSKLPPAETDDGFDDFQEFATPANGNHGQSEDDDDFGD 395
            :|.    :..:|..|||.:: ...:|..|||...:  ||  :|.:|.:..|......:|.|||.|
  Rat   501 QTS----DGLSEECPLEGESGGKDSEPDSKLKNGQ--DG--EFGDFDSVPNTQGSAFQDSDDFAD 557

  Fly   396 F--AAP------------------------------------------------VVTP------- 403
            |  |.|                                                :.||
  Rat   558 FSSAGPSQAVDWNAFEDEQKDSCSWAAFGDQQATESHHRKEVWQSHRTDGTLDTLGTPRTHSVSS 622

  Fly   404 -------VSVPPPPPPAAVHLSIDERVKPVLDMMFPQP---------------TELDSKSMDNRR 446
                   .|.....|..:...::..|::.:.:..||..               .|.:...:..|.
  Rat   623 AASKGAVASGHLQEPATSAQTALLNRLERIFEACFPSVFVPDAEEEVTSLKHLLETNYSPVKARE 687

  Fly   447 PLAQCQRF-----NFGAIEHAQALDYQWSSSEMRHALVRSLGIDSRNILF-GDKWNS-SMPRFAA 504
            .||:|...     ....|..|..|.|||..|.....|:.|||||:||||| |:|... .:|.:||
  Rat   688 ALAECGELRDVWAELQDIHDAHGLRYQWGGSHSNKKLLCSLGIDTRNILFTGNKKQPVIVPMYAA 752

  Fly   505 NLSF-----DPLKPL----KPQSTGAASSLEPISN---STSYQESHVQTLQLEQLDQLTVVANAD 557
            .|..     :|||||    |..|.|..:.:.|..|   |..:|||    |...|.|.
  Rat   753 GLGMLEPTKEPLKPLSAAEKIASIGQTTIMTPEMNTCTSDPFQES----LPPVQFDW-------- 805

  Fly   558 KINLVTSNSHTNNNNDNGDN-----DVAAPVDQLDCM--------PPVMDLMTHNDHNLTIDLHH 609
                 :|:..||..:.:|.:     |...|||.....        |.:.:|.|......|..|..
  Rat   806 -----SSSGLTNPLDASGGSALLNLDFFGPVDDSSSSSSTIPGVDPELYELTTAKLETSTSSLRV 865

  Fly   610 SPSLTHFATICNNNNNDNNNPNNLNNNHAKNTATMTITINTNLT-AHDALLDFRLENAAATTASQ 673
            :.:.....:.....:.....|.  ...|....|...|....:|| .|..:|.|. .....:|:||
  Rat   866 TDAFAKLMSTVEKTSTSTRKPK--REEHLSEEAVKVIVSLPDLTFMHAKVLMFP-ATLTPSTSSQ 927

  Fly   674  673
              Rat   928  927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Afti	NP_001356916.1	Clathrin_bdg	459..516	CDD:464467	29/67 (43%)
Aftph	XP_006251594.1	Clathrin_bdg	696..766	CDD:464467	26/69 (38%)