DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PR-Set7 and egg

DIOPT Version :9

Sequence 1:	NP_001247100.1	Gene:	PR-Set7 / 41743	FlyBaseID:	FBgn0011474	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_611966.3	Gene:	egg / 37962	FlyBaseID:	FBgn0086908	Length:	1262	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	75/329 - (22%)
Similarity:	117/329 - (35%)	Gaps:	69/329 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 TTTAAVAACKSRRRLNQPKPQAPYQPQLQKPPSQQQQQQQD------------DIVVVLDDDDDE 450
            |.:.|:||..|.|:      |.||..:....|.:...:.:|            .::|.:|.|...
  Fly    60 THSEAIAATGSTRK------QCPYGGKAPDEPGKLADESEDRKGENTKAIASSPVLVAVDSDSSV 118

  Fly   451 GDDEDDVRALIKAAEERENQNKAPATANSNKAGMKTMLKPAPVKSKTKSKGPTKGQPPLPLAATN 515
            ...|..|:  ..:|.|.|.....|...|...|.....:..:.:.|.|....|.|.:      .||
  Fly   119 ELIESPVK--FSSANESEKDPPKPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDE------KTN 175

  Fly   516 -GNREMTDFFPVRRSVRKTKTAVKEEW-----MRG---------LEQAVLEERCDGLQVRHFMGK 565
             .|.:......|.:.|.::.:...||:     ::|         .|..:::::.|.|:|.  :.|
  Fly   176 KENEQEPPGMEVDQDVEESISRPAEEYKIENTLKGHKRISLTEIEEHKIVDKKDDVLEVE--LEK 238

  Fly   566 GRGVVADRPFKRNEFVVEYVGDLISIGE-----AAEREKRYALDENAGCYMYYFKHKS--QQY-- 621
            |....|....|.|..:.:  ||:....|     ..:..|:|.|...|....|....||  ||:
  Fly   239 GTAPKAAEDEKLNALLSD--GDVFYDKECVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLC 301

  Fly   622 --CIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRPH-----LVLLAKDDIEPGEELTYDYGDRS 679
              |.|..:|       :....||.||.|..|:.:..|     .|.|...| |..||...:..|.|
  Fly   302 MGCHDTAMD-------LYEEYAGQLMAKQPLLLKDFHQDHADFVALDSSD-EEEEEKQPEKSDFS 358

  Fly   680 KESL 683
            |..|
  Fly   359 KNKL 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PR-Set7	NP_001247100.1	SET	566..676	CDD:279228	32/125 (26%)
egg	NP_611966.3	HMT_MBD	823..879	CDD:238689
		Pre-SET	901..1013	CDD:282838
		SET	1022..1239	CDD:214614
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930