Protein Alignment Set8 and set-12

DIOPT Version :10

• Sequence 1: NP_650354.1
• Gene: Set8 / 41743
• FlyBaseID: FBgn0011474
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_509306.2
• Gene: set-12 / 187229
• WormBaseID: WBGene00019584
• Length: 389
• Species: Caenorhabditis elegans
• Alignment Length: 214
• Identity: 58/214 - (27%)
• Similarity: 80/214 - (37%)
• Gaps: 53/214 - (24%)

  Fly   512 AATNGNREMT-------------DFFPVRRSV---------RK----TKTAVK-------EEWMR 543
            |:||...::|             .|||..|.:         ||    |.|:.|       ||...
 Worm     6 ASTNKKTQLTKKNNSVFVYNTDPKFFPNTRRMDYSFICSPKRKTGLLTVTSCKCGTDCTTEECSN 70

  Fly   544 GLEQAVLEERCDGLQVRHFM--------------GKGRGVVADRPFKRNEFVVEYVGDLISIGEA 594
            ..........|...:.:.|.              |.|.|:.|.......:.::||.|:.|:..|.
 Worm    71 FANHRECPRGCSNCENQRFRKRQFCGVETFLTDNGIGHGLRATEEIATGKLILEYRGEAITKAEH 135

  Fly   595 AEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLIKQRP--HL 657
            .:|.|||..|   |....|.....:.|.:|.| ..|...|.||||...|.:.||..:..||  .|
 Worm   136 NKRVKRYKKD---GIKHSYSFEVGRNYYVDPT-RKGNSARFINHSCNPNALVKVWTVPDRPMKSL 196

  Fly   658 VLLAKDDIEPGEELTYDYG 676
            .:.|...|:||||:|:|||
 Worm   197 GIFASKVIKPGEEITFDYG 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set8	NP_650354.1	SET_SETD8	539..678	CDD:380926	45/154 (29%)
set-12	NP_509306.2	AWS	53..94	CDD:197795	7/40 (18%)
		SET	97..236	CDD:394802	41/123 (33%)