Protein Alignment Set8 and trx

DIOPT Version :10

• Sequence 1: NP_650354.1
• Gene: Set8 / 41743
• FlyBaseID: FBgn0011474
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_061504113.1
• Gene: trx / 1273224
• VectorBaseID: AGAMI1_001889
• Length: 4900
• Species: Anopheles gambiae
• Alignment Length: 869
• Identity: 178/869 - (20%)
• Similarity: 295/869 - (33%)
• Gaps: 270/869 - (31%)

  Fly    10 PAKEAASSSSGGASSGSGIP--VDQALPLNVAGNLLEDQYFASPKRKDCRL---MKVTQNGQLPE 69
            |:...|.|.. |.|:.|..|  ||:   :.:||.  |::...|..:.:.||   :|..:...||.
Mosquito  4076 PSNHPAQSPY-GVSTPSASPNDVDR---MKLAGQ--EEKLLPSAGKPNSRLEIEIKPIEIAPLPS 4134

  Fly    70 ATMMAHNKDNKAGRTIGVPLATRSQTRTIENFFKANAAAKDSQKTIHTE-----EQLNLGNQE-- 127
            | :|.....|.:.....:|.|.:.|.:...:...:.|.|::...::..|     |||....|:
Mosquito  4135 A-LMTPTTTNGSCTPSPLPPAMQQQQQQDSSPMVSLAQAEEQANSMLMEMEEQTEQLQQQQQQDH 4198

  Fly   128 LKLDDEEL------------NGQI------KLDDEVLKLADKQI--------------------- 153
            |:...|.|            ||.:      .||.:...:| .||
Mosquito  4199 LQQSHEPLTPSFQFSLSFDGNGTLIPLGGGPLDPQQPTMA-AQIEIKPILPPTTDGLQSPQQQTT 4262

  Fly   154 ----NENLPFADEVDAKAEQKL--MDEELQQVVEELLFDGSSRA--------------------- 191
                :::|..|:..|.:..|::  :...|:...:|:|.:|...:
Mosquito  4263 TLMSHDSLEVAERRDTEETQRIDELKHSLEAETQEMLAEGHEASLCGDSGAGGSCGAASPSLNDG 4327

  Fly   192 SSNSPFYQH--------------------DMDVMQEIQQTPEIP---------HIKKVTEPLEGL 227
            .|:||..:|                    .||..:.::|:.|:.         |.:.:....|
Mosquito  4328 ESDSPEIKHKISEILDNLEQQTSQEGEQLQMDAFESLRQSKELQQEHHHHHHHHHRAIETDAE-- 4390

  Fly   228 GSLADFQTHRSALRDSHSSTHSSSTDNIFLQEPVLTLDIDRTPTKASSIKI--------NRSFEL 284
             ..|:.:...:.||:...|:.:||        |.|.       |.|:::.:        |.:...
Mosquito  4391 -CAAETERLVAELREEFQSSAASS--------PSLA-------TTATTVPLMTVVEQQSNETGAA 4439

  Fly   285 AGAVFSSPPSVLNACLN-----------GRFNQIV---SLNGQKEALDLPHFDLDQHDSSSCDSG 335
            .|...:...|:|....:           |.|..:|   |..|...|         .||..|
Mosquito  4440 GGGTLADQQSLLAISSSMFEPKMKPDEAGCFRDVVERSSFGGCGPA---------AHDFDS---- 4491

  Fly   336 VACGLTANTESPA-GQPRRRKPATPHRILCPSPIK---TALKVTGGICKVGSADPLSPRKSPRKL 396
            ||.....:.||.. |:.|:.:|:...:   |||.:   ..:::...:.:..|...|.|:
Mosquito  4492 VALLHGGDAESVLFGKIRQPEPSPMSQ---PSPTEHHHQQMQLDEELQQYTSVQQLPPQ------ 4547

  Fly   397 PTTTAAVAACKSRRRLNQPKPQAPYQPQLQKPPSQQQQQQQDDIVVVLDDDDDEGDDEDDVRALI 461
            |:...|.||         |||||  .|:...|....:.|.||....   ......:..|.:...:
Mosquito  4548 PSVQTAAAA---------PKPQA--VPRPTSPKLLYEIQSQDGFTY---KSTSIAEIWDKLFEAV 4598

  Fly   462 KAAEERENQNKAP-----ATANSNKAGMKT-----MLKPAPVKSKTKSKGP------TKGQPPLP 510
            :.|.........|     ..|.....|:||     :|:..|...|.....|      |.|....|
Mosquito  4599 QLARRAHGLAALPDGQLKEMAGVQMLGLKTNAIRYLLEQLPGVEKCSQYSPLYHKKQTGGIGGGP 4663

  Fly   511 ------------LAATNGNREMTDFFPVRR-----SVRKTKTAVKEE-----WM----------- 542
                        |.|..|..|..|:|...:     :.|......:.|     |:
Mosquito  4664 YGAGGAGAGVNGLGANGGASEYADYFEDLQENPYGTARCEPYGTRSEYDMFSWLASRHRKQPMPI 4728

  Fly   543 --RGLEQAVLEERCDG----LQVRHFMGK---------------GRGVVADRPFKRNEFVVEYVG 586
              :.::..::..|..|    :.:|:...|               |||:..:|..:..|.|:||.|
Mosquito  4729 VAQNIDDTIIPRRGSGSNLPMAMRYRTLKESSKESVGVYRSHIHGRGLFCNRDIEAGEMVIEYAG 4793

  Fly   587 DLISIGEAAEREKRYALDENAGCYMYYFKHKSQQYCIDATVDTGKLGRLINHSRAGNLMTKVVLI 651
            :||. ....::.:||......||||:..   .:.:.:|||: .|...|.||||...|..:|||.|
Mosquito  4794 ELIR-STLTDKRERYYDSRGIGCYMFKI---DENFVVDATM-RGNAARFINHSCEPNCYSKVVDI 4853

  Fly   652 KQRPHLVLLAKDDIEPGEELTYDY 675
            ....|:::.|...|..||||||||
Mosquito  4854 LGHKHIIIFALRRIVQGEELTYDY 4877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set8	NP_650354.1	SET_SETD8	539..678	CDD:380926	48/174 (28%)
trx	XP_061504113.1	None