DRSC/TRiP Functional Genomics Resources

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Protein Alignment su(Hw) and Zfp410

DIOPT Version :9

Sequence 1:NP_001247098.1 Gene:su(Hw) / 41740 FlyBaseID:FBgn0003567 Length:941 Species:Drosophila melanogaster
Sequence 2:NP_659082.1 Gene:Zfp410 / 52708 MGIID:1289280 Length:478 Species:Mus musculus


Alignment Length:522 Identity:122/522 - (23%)
Similarity:182/522 - (34%) Gaps:178/522 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 EKKGKLL--GVENISPPKDKRPATRMKLLNDVGAG-EDSEASTTTTTSRTPSNKQEKRGSVAGSR 70
            |.|.:||  .|:|.|.|              :|.| .:|||...|..|..|..:..:     .||
Mouse     7 ESKPELLVQFVQNTSIP--------------LGQGLVESEAKDITCLSLLPVTEASE-----CSR 52

  Fly    71 IKILNEEILGTPKTEKRGATKSTAPAASTVKILNEKKTPSATVTAVETTKIKTSPSKRKKMEHYV 135
            :.:.:|       |.....:....|:::.::.|.....|....|..:|  ::.||.        .
Mouse    53 LMLPDE-------TPNHANSSKEVPSSAVLRSLQVNVGPDGEETRAQT--VQKSPE--------F 100

  Fly   136 LQAVKSENTKADTTVTVVTEEDDTIDFILADDEEVVPGRIENNNGQEIVVTEDD-EDLGEDG-DE 198
            |...:|.:...|      .:..|:..|||.:......|    ::.:..|..:|: ||.|.|. ..
Mouse   101 LTTPESPSLLQD------LQPSDSTSFILLNLTRAGLG----SSAEHFVFVQDETEDSGADFLSA 155

  Fly   199 DGEDSSGKGNSSQTKIKEIVEHVCGKCYKTFRRVQSLKKHLEFCRYDSGYHLRKADMLKNLEKIE 263
            :..|||                     ...|.|||.|       .:||.....:|.:.||.:   
Mouse   156 ESTDSS---------------------IPWFLRVQEL-------AHDSLIAATRAQLAKNAK--- 189

  Fly   264 KDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANL 328
                          ...:.:..|||                                        
Mouse   190 --------------TGSNGENVHLG---------------------------------------- 200

  Fly   329 RSEALLALHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLD 393
                         ...|:|       ||   |..|.:.:|...|        :.:.|||.|....
Mouse   201 -------------SGDGQP-------KD---SGPLPQAEKKLKC--------TVEGCDRTFVWPA 234

  Fly   394 NLRSHLKQHLGTQVVKKPEYMC--HTCKNCFYSLSTLNIHIRTHTGEKPFDC--DLCDKKFSALV 454
            :.:.|||.|...:     .::|  ..|...||.|..|.:|:|||.|||||.|  ..|.|:|:...
Mouse   235 HFKYHLKTHRNER-----SFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAG 294

  Fly   455 ALKKHRRYHTGEKPYSCTV--CNQAFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSK 517
            .||.|||.||||||:.|..  |.::||....|.:|:..|:||:||:|..|||:|.|:.....|.:
Mouse   295 NLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMR 359

  Fly   518 TH 519
            .|
Mouse   360 KH 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
su(Hw)NP_001247098.1 C2H2 Zn finger 292..313 CDD:275368 0/20 (0%)
COG5048 <312..517 CDD:227381 64/210 (30%)
C2H2 Zn finger 321..341 CDD:275368 0/19 (0%)
zf-C2H2 348..368 CDD:278523 4/19 (21%)
C2H2 Zn finger 350..368 CDD:275368 4/17 (24%)
C2H2 Zn finger 382..402 CDD:275368 7/19 (37%)
C2H2 Zn finger 415..435 CDD:275368 8/21 (38%)
zf-H2C2_2 428..451 CDD:290200 13/24 (54%)
C2H2 Zn finger 443..463 CDD:275368 9/21 (43%)
zf-H2C2_2 455..479 CDD:290200 13/25 (52%)
COG5048 <467..620 CDD:227381 21/55 (38%)
C2H2 Zn finger 471..491 CDD:275368 6/21 (29%)
zf-H2C2_2 484..508 CDD:290200 12/23 (52%)
C2H2 Zn finger 499..519 CDD:275368 7/19 (37%)
C2H2 Zn finger 525..545 CDD:275368
C2H2 Zn finger 555..572 CDD:275368
C2H2 Zn finger 598..615 CDD:275371
Zfp410NP_659082.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 84..113 8/44 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 187..214 10/106 (9%)
SFP1 <189..300 CDD:227516 40/203 (20%)
C2H2 Zn finger 221..243 CDD:275368 8/29 (28%)
C2H2 Zn finger 251..273 CDD:275368 8/21 (38%)
zf-H2C2_2 265..292 CDD:372612 14/26 (54%)
C2H2 Zn finger 281..303 CDD:275368 9/21 (43%)
zf-H2C2_2 295..321 CDD:372612 13/25 (52%)
C2H2 Zn finger 311..333 CDD:275368 6/21 (29%)
zf-H2C2_2 325..350 CDD:372612 12/24 (50%)
C2H2 Zn finger 341..361 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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