DRSC/TRiP Functional Genomics Resources

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Protein Alignment su(Hw) and Sry-delta

DIOPT Version :9

Sequence 1:NP_001247098.1 Gene:su(Hw) / 41740 FlyBaseID:FBgn0003567 Length:941 Species:Drosophila melanogaster
Sequence 2:NP_524581.1 Gene:Sry-delta / 43572 FlyBaseID:FBgn0003512 Length:433 Species:Drosophila melanogaster


Alignment Length:592 Identity:120/592 - (20%)
Similarity:185/592 - (31%) Gaps:237/592 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 GATKSTAPAASTVKILNEKKTPSATVTAVET---TKIKTSPSKR--------------------- 128
            |::.|......:.|:.:.:||.|..:|.:..   |::...|..|                     
  Fly    16 GSSSSMRYETLSAKVPSSQKTVSLVLTHLANCIQTQLDLKPGARLCPRCFQELSDYDTIMVNLMT 80

  Fly   129 --KKMEHYVLQAVKSENTKADTTVTVVTEE------DDTIDFILADDE------EVVPGRIENNN 179
              |::...:..|:|||....::...::.||      |...|   ||.|      |:|..:.|::.
  Fly    81 TQKRLTTQLKGALKSEFEVPESGEDILVEEVEIPQSDVETD---ADAEADALFVELVKDQEESDT 142

  Fly   180 --GQEIVVTEDDEDLGEDGDE---------DGEDSSGKGNSSQTK-IKEIVEHVCGKCYKTFRRV 232
              .:|.|..|::|| .:|.||         |.|...||.:..:.: .|:.|:..|..|.|.    
  Fly   143 EIKREFVDEEEEED-DDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQECTTCGKV---- 202

  Fly   233 QSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPK 297
                       |:|.|.|:|                                             
  Fly   203 -----------YNSWYQLQK--------------------------------------------- 211

  Fly   298 SFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLALHEEQHKSRGKPYACKICGKDFTRSYH 362
                      ||...||:..:..|.||....|.|..|.||...|:.:.:. .|:.|.|.|:|..:
  Fly   212 ----------HISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEK-QCRYCPKSFSRPVN 265

  Fly   363 LKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLST 427
            ..|                                                              
  Fly   266 TLR-------------------------------------------------------------- 268

  Fly   428 LNIHIRTHTGEKPFDCDLCDKKFSALVALKKHR-RYHTGEKPYSCTVCNQAFAVKEVLNRHMKRH 491
               |:|.|..:|.:.|:.|..:||....|..|| |:...|.|..|::||.:|..::..|.|...|
  Fly   269 ---HMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIH 330

  Fly   492 TGERP-HKCDECGKSFIQATQLRTHSKTHIRPFPCEQCDEKFKTEKQL--ERHVKTHSRTKRPVF 553
            ...|| |.|..|.|||.:...|:.|.|||.........:|....|:|:  |.||           
  Fly   331 KENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELHV----------- 384

  Fly   554 SCAECKRNFRTPALLKEHMDEGKHSPKQQRSSMRSAVKIMERTD-----CAICDKNFDSSDTLRR 613
                             .:||          |..:...||...|     |.||:.||::...|..
  Fly   385 -----------------DVDE----------SEAAVTVIMSDNDENSGFCLICNTNFENKKELEH 422

  Fly   614 HIRTVHE 620
            |::..|:
  Fly   423 HLQFDHD 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
su(Hw)NP_001247098.1 C2H2 Zn finger 292..313 CDD:275368 2/20 (10%)
COG5048 <312..517 CDD:227381 48/206 (23%)
C2H2 Zn finger 321..341 CDD:275368 8/19 (42%)
zf-C2H2 348..368 CDD:278523 6/19 (32%)
C2H2 Zn finger 350..368 CDD:275368 6/17 (35%)
C2H2 Zn finger 382..402 CDD:275368 0/19 (0%)
C2H2 Zn finger 415..435 CDD:275368 2/19 (11%)
zf-H2C2_2 428..451 CDD:290200 6/22 (27%)
C2H2 Zn finger 443..463 CDD:275368 8/20 (40%)
zf-H2C2_2 455..479 CDD:290200 9/24 (38%)
COG5048 <467..620 CDD:227381 40/160 (25%)
C2H2 Zn finger 471..491 CDD:275368 6/19 (32%)
zf-H2C2_2 484..508 CDD:290200 11/24 (46%)
C2H2 Zn finger 499..519 CDD:275368 8/19 (42%)
C2H2 Zn finger 525..545 CDD:275368 6/21 (29%)
C2H2 Zn finger 555..572 CDD:275368 0/16 (0%)
C2H2 Zn finger 598..615 CDD:275371 6/16 (38%)
Sry-deltaNP_524581.1 COG5048 <205..360 CDD:227381 56/275 (20%)
C2H2 Zn finger 225..245 CDD:275368 8/19 (42%)
C2H2 Zn finger 253..273 CDD:275368 8/84 (10%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
C2H2 Zn finger 310..327 CDD:275370 5/16 (31%)
zf-C2H2 337..359 CDD:278523 9/21 (43%)
C2H2 Zn finger 339..359 CDD:275368 8/19 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BMXZ
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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