DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(Hw) and CG11902

DIOPT Version :9

Sequence 1:	NP_001247098.1	Gene:	su(Hw) / 41740	FlyBaseID:	FBgn0003567	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_651389.3	Gene:	CG11902 / 43070	FlyBaseID:	FBgn0028647	Length:	1426	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	117/478 - (24%)
Similarity:	184/478 - (38%)	Gaps:	137/478 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 CGKCYKTFRRVQSLKKH---------LEFCRYDSGYHLRKADMLKNL-------EKIEKDAVVME 270
            ||||.::||..:.|.:|         :..||:.:....|:|::|:::       .::.....:::
  Fly   967 CGKCNRSFRMQKDLTRHTLMHGQESNIFRCRWCARRFYRRANLLQHIARHGISVSQLPYAEAILD 1031

  Fly   271 --------KKDICFCCSESYDTFHLGHINCPDCPK------------SFKTQTSYERHIFITHSE 315
                    ||..|..|:.|:.|.....::....|.            |...|..:|..::.:.::
  Fly  1032 SYVNPGGRKKVECRVCNVSFPTIAALRLHLETMPAGSHHDYSSLQNYSITNQMGFEMDLYDSETD 1096

  Fly   316 FSD-------------FPCSICNANLRSEALLALHEE--------------------------QH 341
            ..|             :.|::|......:..|..|::                          .|
  Fly  1097 DEDSRTHIKPPGAPSSYTCNMCQLRCLRKFELYQHQQAMHRMEKISDGCDSCLFKSVCPEIISHH 1161

  Fly   342 K-----SRGKPYACKICGKDFTRSYHLKRH-------------QKYSSCSSNETDT----MSCKV 384
            |     :|.|.:.|..||..|....:|..|             .:....|.:|..|    ..|.:
  Fly  1162 KRTQCENREKQFKCTRCGYKFMWESNLLLHMDLQHVKTEDQELDESKEASGDEPKTEGQVFQCGL 1226

  Fly   385 CDRVFYRLDNLRSHLKQHLG----TQVVKKP----------EYMCHTCKNCFYSLSTLNIHIRTH 435
            |.|.:.|.|.|.:|||:..|    ....|.|          .::|..|.....|.|.|.||:|.|
  Fly  1227 CTRKYNRKDRLTAHLKKFHGPDCKPSTAKTPNRPISPKEPKRFLCAFCGKAVSSSSNLIIHMRRH 1291

  Fly   436 TGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCD 500
            ||||||.|:.|...|.....|:.|||.||||:|:.||||.:.||....|.:||:.|:||||:||.
  Fly  1292 TGEKPFKCEYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCT 1356

  Fly   501 ECGKSFIQATQLRTHSKTHI--RPFPCEQCDEKFKTEKQLERHVKTHSRTKRPVFSCAECKRNFR 563
            .|.|||.|:..|..|.:.|.  ||:.|..|.|:|.....|:.|
  Fly  1357 YCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNH---------------------- 1399

  Fly   564 TPALLKEHMDEGKHSPKQQRSSM 586
              .:.:.|.:||:.|.:..|.::
  Fly  1400 --RMQQSHYEEGQESVEPTRRTV 1420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(Hw)	NP_001247098.1	C2H2 Zn finger	292..313	CDD:275368	4/32 (13%)
		COG5048	<312..517	CDD:227381	80/279 (29%)
		C2H2 Zn finger	321..341	CDD:275368	4/45 (9%)
		zf-C2H2	348..368	CDD:278523	6/32 (19%)
		C2H2 Zn finger	350..368	CDD:275368	6/30 (20%)
		C2H2 Zn finger	382..402	CDD:275368	9/19 (47%)
		C2H2 Zn finger	415..435	CDD:275368	8/19 (42%)
		zf-H2C2_2	428..451	CDD:290200	13/22 (59%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		zf-H2C2_2	455..479	CDD:290200	13/23 (57%)
		COG5048	<467..620	CDD:227381	38/122 (31%)
		C2H2 Zn finger	471..491	CDD:275368	9/19 (47%)
		zf-H2C2_2	484..508	CDD:290200	14/23 (61%)
		C2H2 Zn finger	499..519	CDD:275368	8/19 (42%)
		C2H2 Zn finger	525..545	CDD:275368	6/19 (32%)
		C2H2 Zn finger	555..572	CDD:275368	0/16 (0%)
		C2H2 Zn finger	598..615	CDD:275371
CG11902	NP_651389.3	zf-AD	6..83	CDD:285071
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368
		C2H2 Zn finger	896..918	CDD:275368
		C2H2 Zn finger	926..947	CDD:275368
		C2H2 Zn finger	967..987	CDD:275368	8/19 (42%)
		C2H2 Zn finger	996..1016	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1044..1063	CDD:275368	4/18 (22%)
		C2H2 Zn finger	1224..1244	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1271..1291	CDD:275368	8/19 (42%)
		zf-H2C2_2	1283..1306	CDD:290200	13/22 (59%)
		COG5048	1295..>1367	CDD:227381	36/71 (51%)
		C2H2 Zn finger	1299..1319	CDD:275368	7/19 (37%)
		zf-H2C2_2	1311..1336	CDD:290200	14/24 (58%)
		C2H2 Zn finger	1327..1347	CDD:275368	9/19 (47%)
		zf-H2C2_2	1340..1364	CDD:290200	14/23 (61%)
		C2H2 Zn finger	1355..1375	CDD:275368	8/19 (42%)
		zf-H2C2_2	1367..1392	CDD:290200	9/24 (38%)
		C2H2 Zn finger	1383..1401	CDD:275368	6/41 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100