DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(Hw) and CG6654

DIOPT Version :9

Sequence 1:	NP_001247098.1	Gene:	su(Hw) / 41740	FlyBaseID:	FBgn0003567	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	668	Identity:	156/668 - (23%)
Similarity:	251/668 - (37%)	Gaps:	188/668 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DVGAGE---DSEASTTTTTSRTPSNKQEK-----RGSVAGS---RIKILN-----EEILGTPKTE 85
            |.|:|.   |.....|.|..|...|..||     ...::..   :||..|     .::|.....|
  Fly    22 DGGSGSCLADMIREFTKTKPRRNDNLPEKVCLSCLSEISNCYTFKIKCENSSRTLRQLLPNALPE 86

  Fly    86 KRGATKS-TAPAASTVKILNEKK-TPSATVTAVETTKIKTSPSKRKKMEHYVLQAVKSENTK-AD 147
            :..:..| :.|.|:|.:.:.... .|.....:|:|..:.|:.::              :||. ..
  Fly    87 EPDSKVSISCPVATTDQAVQTTSWEPDRCTASVQTDAVTTTDAE--------------QNTSLIK 137

  Fly   148 TTVTVVTE---EDDTIDFILADD--EEV------VPGRIENNNGQEIVVTE-------DDEDLGE 194
            :|::|..:   |.:..|:.|.|:  |:.      |.|.:::.  :|:|.|:       ||.:|.:
  Fly   138 STISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGNLKDE--KEVVFTQTNVIYEGDDHELEQ 200

  Fly   195 DGDE------DGEDSSGKGNSSQTKIKEIVEHVCGKCYKTFRRVQSLKKHLE-FCRYDSGYHLRK 252
            ...|      :|.|:..          ||:.       .|..:|.:.|...: ..:.::..|...
  Fly   201 QIRECNLAIFEGVDNEA----------EIIT-------VTAPQVTTRKSAAKLLTQQENDKHQTP 248

  Fly   253 ADMLKNLEKIEKDAVVME-----------KKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYE 306
            ....:...::||:.|...           |:|:                  |..|.| ..:.|.:
  Fly   249 VGSKEEARELEKEQVPQSAKRTSRRRGVVKQDV------------------PATPPS-DAEPSPK 294

  Fly   307 RHIFITHSEFS----------------------DFPCSICNANLRSEALLALHEEQHKSRGKPYA 349
            :|...|..:.|                      .:.|..|||....|..|.:|..|.....:.|.
  Fly   295 QHRLGTQRKLSAPRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYK 359

  Fly   350 CKICGKDFTRSYHLKRHQKYSS----------CSSNETDTM------------SCKVCDRVFYRL 392
            |..|.|.|....||..||....          |.|.|..:.            .|.:|.:||..|
  Fly   360 CNECEKVFVSPDHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTML 424

  Fly   393 DNLRSHLKQHLGTQVVKKP---------------------------EYMCHTCKNCFYSLSTLNI 430
            ..||.|::.|.|    :||                           .:.|..|.:.|.:.:.|..
  Fly   425 STLRDHMRIHTG----EKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTS 485

  Fly   431 HIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGER 495
            |.|||||:|||:|::|..:|:...:|.||:|.||||:||:|.:|...|....||..|.:.|||||
  Fly   486 HARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGER 550

  Fly   496 PHKCDECGKSFIQATQLRTHSKTH--IRPFPCEQCDEKFKTEKQLERHVKTHSR-TKRPV-FSCA 556
            |:.|..|.|:|.|....:.|.:||  .|.:.|..|:|:||:..::..|:..|.: .||.| |:..
  Fly   551 PYVCPFCSKTFTQRGDCQMHQRTHQGERIYICPVCNEEFKSMPEMRSHLAGHEQHDKRLVHFTFL 615

  Fly   557 ECKRNFRTPALLKEHMDE 574
            ..|.|  ....|:|.::|
  Fly   616 SNKEN--GSGALEEELNE 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(Hw)	NP_001247098.1	C2H2 Zn finger	292..313	CDD:275368	5/20 (25%)
		COG5048	<312..517	CDD:227381	78/275 (28%)
		C2H2 Zn finger	321..341	CDD:275368	7/19 (37%)
		zf-C2H2	348..368	CDD:278523	8/19 (42%)
		C2H2 Zn finger	350..368	CDD:275368	7/17 (41%)
		C2H2 Zn finger	382..402	CDD:275368	8/19 (42%)
		C2H2 Zn finger	415..435	CDD:275368	6/19 (32%)
		zf-H2C2_2	428..451	CDD:290200	12/22 (55%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		zf-H2C2_2	455..479	CDD:290200	12/23 (52%)
		COG5048	<467..620	CDD:227381	39/112 (35%)
		C2H2 Zn finger	471..491	CDD:275368	6/19 (32%)
		zf-H2C2_2	484..508	CDD:290200	12/23 (52%)
		C2H2 Zn finger	499..519	CDD:275368	6/19 (32%)
		C2H2 Zn finger	525..545	CDD:275368	6/19 (32%)
		C2H2 Zn finger	555..572	CDD:275368	4/16 (25%)
		C2H2 Zn finger	598..615	CDD:275371
CG6654	NP_650429.1	zf-AD	6..79	CDD:285071	13/56 (23%)
		C2H2 Zn finger	331..354	CDD:275368	8/22 (36%)
		COG5048	<357..570	CDD:227381	67/216 (31%)
		C2H2 Zn finger	360..380	CDD:275368	8/19 (42%)
		C2H2 Zn finger	385..406	CDD:275370	3/20 (15%)
		C2H2 Zn finger	414..434	CDD:275368	8/19 (42%)
		zf-H2C2_2	427..451	CDD:290200	7/27 (26%)
		C2H2 Zn finger	442..490	CDD:275368	6/47 (13%)
		C2H2 Zn finger	470..487	CDD:275368	4/16 (25%)
		zf-H2C2_2	482..507	CDD:290200	13/24 (54%)
		C2H2 Zn finger	498..518	CDD:275368	7/19 (37%)
		zf-H2C2_2	510..534	CDD:290200	12/23 (52%)
		C2H2 Zn finger	526..546	CDD:275368	6/19 (32%)
		zf-H2C2_2	539..563	CDD:290200	12/23 (52%)
		C2H2 Zn finger	554..574	CDD:275368	6/19 (32%)
		C2H2 Zn finger	582..602	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010