DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(Hw) and CG10631

DIOPT Version :9

Sequence 1:	NP_001247098.1	Gene:	su(Hw) / 41740	FlyBaseID:	FBgn0003567	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_609998.1	Gene:	CG10631 / 35262	FlyBaseID:	FBgn0032817	Length:	3781	Species:	Drosophila melanogaster

Alignment Length:	408	Identity:	91/408 - (22%)
Similarity:	135/408 - (33%)	Gaps:	138/408 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 SFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLALHEE---QHKSRGKPYACKICGKDFTR 359
            |:|:....:...|...|:||:|          ||.:|:...|   :.:|.|:           |.
  Fly   225 SYKSNYIDDNTPFADFSKFSEF----------SEDMLSPKVELTVKDESYGR-----------TT 268

  Fly   360 SYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCK-NCFY 423
            |..|:|.|:  |...||:..: |:.|..||:                  ||..|:.|..: ||
  Fly   269 SSFLRRKQQ--SDRGNESLPI-CQRCKEVFF------------------KKQVYLRHVAESNC-- 310

  Fly   424 SLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHM 488
                         |.:.:|                          :.|:.|..:|...|.|.||.
  Fly   311 -------------GIQEYD--------------------------FKCSTCPMSFMTTEELQRHK 336

  Fly   489 KRHTGER--PHKCDECGKSFIQATQLRTHS--KTHIRPFPCEQCDEKFKTEKQLERHVKTHSRTK 549
            ..|..:|  .||  .|||.|....:...|.  :.....|.|..|...|.|.:||..|:..|...:
  Fly   337 LHHRADRFFCHK--YCGKHFDTIAECEAHEYMQHEYDSFVCNMCSGTFATREQLYAHLPQHKFQQ 399

  Fly   550 RPVFSCAECKRNFRTPALLKEHMDE-----GKHSPKQQRSSMRSAVKIMERTDCAICDKNFDSSD 609
            |  |.|..|:..::|...|.||...     ||:....|.||...:.....:|       |:...|
  Fly   400 R--FDCPICRLWYQTALELHEHRLAAPYFCGKYYTGGQSSSASQSQAQQHQT-------NYKLQD 455

  Fly   610 TLRRHIRTVHECDPDDIFGVEPHPSKRAKKDIESEEVVPVALNTSAGSLISSQTDGNGVVVREFL 674
            .   |:.|:.       ....||     .|...|...:|.   |:|.:.:..|...|
  Fly   456 C---HMATME-------MPTTPH-----HKTTPSGSSLPA---TAALNSLLQQRQAN-------- 494

  Fly   675 VDEGDGAAQ--TITLENE 690
               .||||.  ...::||
  Fly   495 ---ADGAAMFAASAMKNE 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(Hw)	NP_001247098.1	C2H2 Zn finger	292..313	CDD:275368	3/14 (21%)
		COG5048	<312..517	CDD:227381	46/212 (22%)
		C2H2 Zn finger	321..341	CDD:275368	4/22 (18%)
		zf-C2H2	348..368	CDD:278523	4/19 (21%)
		C2H2 Zn finger	350..368	CDD:275368	4/17 (24%)
		C2H2 Zn finger	382..402	CDD:275368	4/19 (21%)
		C2H2 Zn finger	415..435	CDD:275368	3/20 (15%)
		zf-H2C2_2	428..451	CDD:290200	2/22 (9%)
		C2H2 Zn finger	443..463	CDD:275368	0/19 (0%)
		zf-H2C2_2	455..479	CDD:290200	2/23 (9%)
		COG5048	<467..620	CDD:227381	43/161 (27%)
		C2H2 Zn finger	471..491	CDD:275368	7/19 (37%)
		zf-H2C2_2	484..508	CDD:290200	11/25 (44%)
		C2H2 Zn finger	499..519	CDD:275368	5/21 (24%)
		C2H2 Zn finger	525..545	CDD:275368	7/19 (37%)
		C2H2 Zn finger	555..572	CDD:275368	5/16 (31%)
		C2H2 Zn finger	598..615	CDD:275371	2/16 (13%)
CG10631	NP_609998.1	C2H2 Zn finger	288..311	CDD:275368	10/55 (18%)
		C2H2 Zn finger	319..339	CDD:275368	7/19 (37%)
		DM3	584..642	CDD:128933
		DM3	683..738	CDD:128933
		DM3	775..832	CDD:128933
		DM3	945..1000	CDD:128933
		DM3	1038..1096	CDD:128933
		DM3	1145..1198	CDD:128933
		THAP	1236..1308	CDD:214951
		DM3	1349..1406	CDD:128933
		THAP	1424..1493	CDD:214951
		DM3	1538..1596	CDD:128933
		DM3	1683..1739	CDD:128933
		DM3	1778..1831	CDD:128933
		DM3	1980..2033	CDD:128933
		DM3	2147..2202	CDD:128933
		DM3	2308..2365	CDD:128933
		DM3	2434..2491	CDD:128933
		DM3	2539..2598	CDD:128933
		DM3	2622..2680	CDD:128933
		DM3	2718..2775	CDD:128933
		DM3	2907..2965	CDD:128933
		DM3	3098..3155	CDD:128933
		DM3	3227..3284	CDD:128933
		DM3	3396..3452	CDD:128933
		DM3	3544..3601	CDD:128933
		THAP	3621..>3669	CDD:283206
		DM3	3690..3748	CDD:128933
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100