DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(Hw) and si:dkeyp-2e4.6

DIOPT Version :9

Sequence 1:	NP_001247098.1	Gene:	su(Hw) / 41740	FlyBaseID:	FBgn0003567	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_001124126.1	Gene:	si:dkeyp-2e4.6 / 100002333	ZFINID:	ZDB-GENE-061009-50	Length:	271	Species:	Danio rerio

Alignment Length:	175	Identity:	60/175 - (34%)
Similarity:	91/175 - (52%)	Gaps:	4/175 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   345 GKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVK 409
            ||.:.||:||.:||.:.::.||.:..:    |.....|::|.:.|.|.|.|:.|:..|.|.:..:
Zfish    99 GKKFVCKLCGFEFTYNSNMVRHMRIHT----EETPYVCEICGKGFKRQDWLKLHISVHTGVKRKR 159

  Fly   410 KPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVC 474
            |..:.|..|...|:..:.|..|:..|.||:||.|..|||.|.:...|.:|......:|.:||::|
Zfish   160 KKTFGCDQCGKKFHGSTALQSHLNKHRGERPFPCVQCDKSFFSHSDLYRHINDCHSQKKHSCSLC 224

  Fly   475 NQAFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTH 519
            ...|..:..|.:||:.||||||:.|..|||:|........|.|.|
Zfish   225 GNGFTRRTSLLKHMRIHTGERPYSCPHCGKTFPYKYSFEMHLKRH 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(Hw)	NP_001247098.1	C2H2 Zn finger	292..313	CDD:275368
		COG5048	<312..517	CDD:227381	58/171 (34%)
		C2H2 Zn finger	321..341	CDD:275368
		zf-C2H2	348..368	CDD:278523	8/19 (42%)
		C2H2 Zn finger	350..368	CDD:275368	8/17 (47%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..435	CDD:275368	5/19 (26%)
		zf-H2C2_2	428..451	CDD:290200	11/22 (50%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		zf-H2C2_2	455..479	CDD:290200	6/23 (26%)
		COG5048	<467..620	CDD:227381	22/53 (42%)
		C2H2 Zn finger	471..491	CDD:275368	6/19 (32%)
		zf-H2C2_2	484..508	CDD:290200	14/23 (61%)
		C2H2 Zn finger	499..519	CDD:275368	7/19 (37%)
		C2H2 Zn finger	525..545	CDD:275368
		C2H2 Zn finger	555..572	CDD:275368
		C2H2 Zn finger	598..615	CDD:275371
si:dkeyp-2e4.6	NP_001124126.1	COG5048	<98..256	CDD:227381	56/160 (35%)
		C2H2 Zn finger	104..124	CDD:275368	8/19 (42%)
		zf-H2C2_2	116..141	CDD:290200	6/28 (21%)
		C2H2 Zn finger	132..152	CDD:275368	7/19 (37%)
		C2H2 Zn finger	165..185	CDD:275368	5/19 (26%)
		zf-H2C2_2	177..200	CDD:290200	11/22 (50%)
		C2H2 Zn finger	193..241	CDD:275368	15/47 (32%)
		zf-H2C2_2	233..256	CDD:290200	13/22 (59%)
		C2H2 Zn finger	249..269	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910