Protein Alignment IFT54 and traf3ip1

DIOPT Version :10

• Sequence 1: NP_650353.1
• Gene: IFT54 / 41739
• FlyBaseID: FBgn0038221
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001164992.1
• Gene: traf3ip1 / 779507
• XenbaseID: XB-GENE-5871494
• Length: 628
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 195/653 - (29%)
• Similarity: 305/653 - (46%)
• Gaps: 106/653 - (16%)

  Fly     8 AIILETQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENITSRED 72
            |||..||:.|||.|:|||||||||.|||||:|.|:.:..|:.:|.|.||||..|...:|:..::.
 Frog     4 AIIGRTQETLGKVIRKPPLTEKLLGKPPFRYLHDILTEVIRTTGFFKGLYTDSELKSDNVKEKDA 68

  Fly    73 KIRFLQKMIDATKLTTKLDLKVRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVVISHS 137
            ||:||||.||...|.|...|.|:.::||||.|||.|||||||:.....:.|..:..|.:|:...
 Frog    69 KIQFLQKAIDVVALVTGELLTVKPARIVAGHEPEKTNELLQAIGKCCLEKLSSEEAVKRVLAGE- 132

  Fly   138 KTPLTLTKPPK-----ETKNSSKNPSPAGKDEDAKR----RKEKRI-----SPQEQKLRKVKEQV 188
                   ||..     .|..|....|...|:||.||    :||..|     |.:.::...|||:.
 Frog   133 -------KPESRGKSLSTSKSQDKVSREAKEEDRKRNRQDKKESEIRDGSGSRERREKHHVKEEE 190

  Fly   189 SRST-------PPTEKDKASQKKSKAPKDETKLSRQNSKQK----SPSPVKQKSKAKLQPS---- 238
            .::.       ..:|||:..:::....::..|:.::.:|.:    .|...|.|.||:.:.|
 Frog   191 RKNVEKERGRKKESEKDRVGEEERNGLREGEKIDKEINKARDSKLEPERDKIKEKARDRKSDGSR 255

  Fly   239 -TESDNL-------------SQSMSPVEEGSTKPAASESAPSKPEPEMV------------PPLK 277
             .|.|.:             |:...|..:...:.|..:.|..:.|.|.:            |...
 Frog   256 GKEKDRIREKGRDKDHEKERSKEREPERDKRKERAREDEAQREREEEKIRQQERTVRKSKGPDNS 320

  Fly   278 EKEAVVRPVQETPTAPPAEPESRKSSSRSRRSSGS---HRQPEPNPIPNESQSQPAVQSSETSSP 339
            .|.|:..||:|..::  |:.|...::.::.|.|.|   .|:|....:..||.|:...:|:|   |
 Frog   321 PKRALEDPVKENKSS--ADKERLLNAVKTERPSASKLRERRPAKIDVEGESDSEDEKESAE---P 380

  Fly   340 PETNSGEAKREVPLTRENSKEVNQRPRTSLRPPSARPASARPGAPR-RRNVEIVLQPNDQIKMSG 403
            |.|:          .|||....:.....|.|.|  ||.||||..|| ||.....:...::|....
 Frog   381 PATD----------LRENLDVQSPNVIQSRRIP--RPGSARPAPPRLRRQGSAEVPVPERIGSGK 433

  Fly   404 INVKLETFGDLDDDGENLVIIEDSAAHDIVEGGGDEPALE-------GQLDAQGRLVQQILETQK 461
            :...:....:.:||.:..|:.|......      |.|.:|       .:.:..|.||.:||||:|
 Frog   434 VIANVIVDKEKEDDDDEFVVEEAPLQLP------DMPEIELGKRVELREDEKHGALVNKILETKK 492

  Fly   462 ELVNQGAEVEPPP----AQAGRQTS----ARQVNDVRDVVQKLTKSIGPLGKLLDCIPEDFDAMQ 518
            :...| |:.|...    :.||::..    .|::..:|..:|.|.:|..||||::|.:.||.|.||
 Frog   493 DYETQ-ADTENKEKLLLSDAGKKKEKDMVTREIEKLRSSIQTLCRSALPLGKIMDYLQEDVDTMQ 556

  Fly   519 LELTMWRDTYTQASTELKREQTLTASATEPLQHQLQQIQASIAEYRELIDESRHKILQNNARILK 583
            .||.|||....|.:..|.:||::|.:|.|||:.:|.:::..|.|.::.|...:..||:|..:|.|
 Frog   557 NELQMWRRENNQHAKALLQEQSVTETAVEPLKAELAELEQLIKEQQDKICTMKANILRNEEKIQK 621

  Fly   584 LMM 586
            :::
 Frog   622 MVL 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT54	NP_650353.1	MIP-T3	9..119	CDD:463020	59/109 (54%)
		PHA03247	<146..395	CDD:223021	72/307 (23%)
		MIP-T3_C	444..588	CDD:465481	51/151 (34%)
traf3ip1	NP_001164992.1	MIP-T3	5..116	CDD:463020	59/110 (54%)
		PTZ00121	<91..>387	CDD:173412	74/318 (23%)
		SF-CC1	224..>328	CDD:273721	18/103 (17%)
		MIP-T3_C	476..626	CDD:465481	51/150 (34%)