Protein Alignment IFT54 and Traf3ip1

DIOPT Version :10

• Sequence 1: NP_650353.1
• Gene: IFT54 / 41739
• FlyBaseID: FBgn0038221
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_036009757.1
• Gene: Traf3ip1 / 74019
• MGIID: 1921269
• Length: 712
• Species: Mus musculus
• Alignment Length: 719
• Identity: 187/719 - (26%)
• Similarity: 317/719 - (44%)
• Gaps: 160/719 - (22%)

  Fly     8 AIILETQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENITSRED 72
            |::..||:.|||.|::||||||||.|||||:|.|:.:..|:.:|...||||..|...||:..::.
Mouse     4 AVVRRTQEALGKVIRRPPLTEKLLNKPPFRYLHDIITEVIRITGFMKGLYTDAEMKSENVKDKDA 68

  Fly    73 KIRFLQKMIDATKLTTKLDLKVRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVVI--- 134
            ||.||||.||...:.:...|..:.::||||.|||.||||||.:.......|..|..|.:|:.
Mouse    69 KISFLQKAIDVVMMVSGEPLAAKPARIVAGHEPERTNELLQLIGKCCLSKLSSDEAVKRVLAGDK 133

  Fly   135 SHSKTPLTLTKPPKETKNSSKNPSPAGKDEDAKRRKE-KRISPQEQKL----RKVKEQVSRSTPP 194
            ..|:.....|...:|..|.|      ||:|:::..|| ||.|..:::.    .|.||::...:.|
Mouse   134 GDSRGRAQRTSKAQEPNNKS------GKEEESRIHKEDKRSSEAKERSASAEHKQKEELKEDSKP 192

  Fly   195 TEKDKASQKKSKAPKD-------------ETKLSRQNSKQK------------------------ 222
            .||::..:|..:|.:|             |.:.:|..:|.:
Mouse   193 REKERDKEKAKEADRDRHRDPDRDRNRDGEREKARARAKDRDRNNRDRDREAERDRERDRRSEGG 257

  Fly   223 -----------------------------SPSPVKQKSKAKLQPSTESDNLSQSMSPVEEGSTKP 258
                                         :..|.::||:...:|..:|.:..:....:.:||.|.
Mouse   258 KEKERVKDRDRDRDKGRDRERRKSKNGEHTRDPDREKSRDADKPEKKSSSSGEISRKLSDGSFKD 322

  Fly   259 -----------AASESAPSKPEPEMVPPLKEKEAVV--RPVQETPTAPPAEPESRKSSSRSRRS- 309
                       .||.|:..||...     :.|.::.  |..:.:...|..|.|.:.|..::::.
Mouse   323 VKAEMEADISVGASRSSTLKPSKR-----RSKHSLEGRRDSRASDNNPFPEKEHKASYRKAKKDH 382

  Fly   310 ---------------------SGSHRQPEPNPIPNE------------SQSQPAV-QSSETSSPP 340
                                 ||.:.:|:.....:|            ::.:||| |..::.|..
Mouse   383 SMKQLGRKEDNISAKILDSIVSGLNDEPDQETTTSEIDDNSASLWRESAEPEPAVKQKGDSPSDA 447

  Fly   341 ETNSGEAKREVPLTRENSKEVNQRPRTSLRPPSARPASARPGAPRRRNVE----IVLQPNDQIKM 401
            |..:|.|.::.|...||::..::.|.:..|.|  ||.||||..||.:..|    :|:..:...|.
Mouse   448 EVEAGPAGQDKPEVMENAEVPSELPSSLRRIP--RPGSARPAPPRVKRQESTETLVVDRSGSGKT 510

  Fly   402 SGINVKLETFGDLDDDGENLVI-----IEDSAAHDIVEGGGDEPALEGQLDAQGRLVQQILETQK 461
            .. :|.:::....::|.|..|:     :.:.|..|:|..|    .||.: :..|.||::||||:|
Mouse   511 VS-SVIIDSQNSDNEDDEQFVVEAAPQLSEIADIDMVPSG----ELEDE-EKHGGLVKKILETKK 569

  Fly   462 ELVNQGAEVEPPPAQAG----------RQTSARQVNDVRDVVQKLTKSIGPLGKLLDCIPEDFDA 516
            :.......::|...:..          :...::::..:|..:|.|.||..||||::|.|.||.||
Mouse   570 DYEKLQQSLKPGEKERSLIFESAWKKEKDIVSKEIEKLRVSIQTLCKSALPLGKIMDYIQEDVDA 634

  Fly   517 MQLELTMWRDTYTQASTELKREQTLTASATEPLQHQLQQIQASIAEYRELIDESRHKILQNNARI 581
            ||.||.:|.....|.:..|.:||::|.||.|||:.:|.:::..|.:.::.|...:..||:|..:|
Mouse   635 MQNELQLWHSENRQHAEALSQEQSITDSAVEPLKAELSELEQQIRDQQDKICAVKANILKNEEKI 699

  Fly   582 LKLM 585
            .|::
Mouse   700 QKMV 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT54	NP_650353.1	MIP-T3	9..119	CDD:463020	52/109 (48%)
		PHA03247	<146..395	CDD:223021	70/371 (19%)
		MIP-T3_C	444..588	CDD:465481	47/152 (31%)
Traf3ip1	XP_036009757.1	MIP-T3	5..117	CDD:463020	52/111 (47%)
		PTZ00121	<118..392	CDD:173412	48/284 (17%)
		MIP-T3_C	552..706	CDD:465481	48/153 (31%)