Protein Alignment IFT54 and traf3ip1

DIOPT Version :10

• Sequence 1: NP_650353.1
• Gene: IFT54 / 41739
• FlyBaseID: FBgn0038221
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_009303227.1
• Gene: traf3ip1 / 393572
• ZFINID: ZDB-GENE-040426-1146
• Length: 644
• Species: Danio rerio
• Alignment Length: 660
• Identity: 184/660 - (27%)
• Similarity: 298/660 - (45%)
• Gaps: 108/660 - (16%)

  Fly     7 DAIILETQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENITSRE 71
            :::..:||:.|||.|||||||||||.|||||:|.|:||..|:.:|...|||...|...:|:..::
Zfish     3 ESVAKKTQETLGKVIKKPPLTEKLLSKPPFRYLHDIFSEVIRTTGFMKGLYVEAEMKSDNVKDKD 67

  Fly    72 DKIRFLQKMIDATKLTTKLDLKVRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVV--- 133
            .||.||||.||...|.:...|..:.::||||.|||.||||||.:|......|..|..|.:|:
Zfish    68 SKIAFLQKAIDVVMLVSGEPLAAKPARIVAGHEPEKTNELLQVIAKCCLNKLSSDEAVKRVLAGD 132

  Fly   134 -ISHSKTPLTLTKPPKET----------------KNSS-----------KNPSPAGKDEDAKRRK 170
             :.....|.|.....||.                |.||           |:......|:|.:|..
Zfish   133 KLDQKGKPSTSRSQDKENREGREHHRDREERKGIKESSGSREQKDPDQPKDQESKRDDKDRRRDA 197

  Fly   171 EKRISPQEQKLRKVKEQVSRSTPPTEKDKASQKKSKAPKD-------------------ETKLSR 216
            |:....:|::..|.:::....:...||||..:|:.:..||                   |:...|
Zfish   198 ERSDKGRERERTKDRDRDKDKSRDREKDKTREKEREREKDRNREKERERDKDRDKKKERESHKDR 262

  Fly   217 QNSKQKSPSPVKQKSKAKLQPSTESDNLSQSMSPVEEGSTK-PAASESAPSKPEPEMVPPLKEKE 280
            :..|.:.....::|.|.|.:|....:.|.      :.|..| .||.|.:.|||:||:.....:.|
Zfish   263 ERDKDREREKRREKEKDKERPRETEEKLK------DRGDRKIKAAEEISKSKPQPEVASKTHQAE 321

  Fly   281 -----------AVVRPVQ-ETPTAPPAEPESRKSSSRSRRSSGSHRQPEPNPIPNESQSQPAVQS 333
                       :.:..:| |:|:..| .|.|.|...|..::.|.                 ..:.
Zfish   322 TEEAEGGELEPSDLTEIQAESPSRIP-RPSSAKGQRRKPKTGGQ-----------------GTEQ 368

  Fly   334 SETSSPPETNSGEAKREVPLTRENSKEVNQRP-RTSLRPPSARPASARPGAPRRRNVEIVLQPND 397
            .||.|..|..:..|::.:||  ||....:... :|:|.....||:||||.|||.:..|.......
Zfish   369 DETESEGEAEAPSAEKPIPL--ENGDVTDSATLQTTLSRRLPRPSSARPAAPRVKRQESYTDATP 431

  Fly   398 QIKM------SGINVKLETFGDLDDDGENLVIIEDSA--AHDIVEGGGDEPALEGQLDAQGRLVQ 454
            ..::      :.:.:..:...:.:||.:...::|::|  ..|:.|...:...|:|. |..|.||:
Zfish   432 AERLGSGKTPASVILDGKKLSEDEDDEDGQFVVEEAAPPPSDVPEVESNSLELQGD-DKHGGLVK 495

  Fly   455 QILETQKELVNQGAE---------VEPPPAQAGRQTSARQVNDVRDVVQKLTKSIGPLGKLLDCI 510
            :||||:|:..:..:.         |.....:..|:..||::..:|..:|.:.:|..||||::|.|
Zfish   496 KILETKKDYESSPSSKSKEQDRSLVSEASRKKERELVAREIERLRSSIQTVCRSALPLGKIMDYI 560

  Fly   511 PEDFDAMQLELTMWRDTYTQASTELKREQTLTASATEPLQHQLQQIQASIAEYRELIDESRHKIL 575
            .||.|:||.||..||....:.:..|.:||.:|....|||:.:|.:::..|.:.::.|...:..||
Zfish   561 QEDMDSMQNELQSWRRENKENAQALLQEQRITDGVVEPLKVELAELEQLIKDQQDKICAVKSNIL 625

  Fly   576 QNNARILKLM 585
            :|..:|.|::
Zfish   626 KNEEKIQKMV 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT54	NP_650353.1	MIP-T3	9..119	CDD:463020	56/109 (51%)
		PHA03247	<146..395	CDD:223021	68/308 (22%)
		MIP-T3_C	444..588	CDD:465481	47/151 (31%)
traf3ip1	XP_009303227.1	MIP-T3	7..117	CDD:463020	56/109 (51%)
		PRK12678	<130..>257	CDD:237171	21/126 (17%)
		SF-CC1	202..>317	CDD:273721	27/120 (23%)
		PTZ00108	<217..466	CDD:240271	58/274 (21%)
		MIP-T3_C	485..638	CDD:465481	47/152 (31%)