Protein Alignment IFT54 and Traf3ip1

DIOPT Version :10

• Sequence 1: NP_650353.1
• Gene: IFT54 / 41739
• FlyBaseID: FBgn0038221
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_017452029.1
• Gene: Traf3ip1 / 363286
• RGDID: 1309252
• Length: 687
• Species: Rattus norvegicus
• Alignment Length: 702
• Identity: 192/702 - (27%)
• Similarity: 309/702 - (44%)
• Gaps: 151/702 - (21%)

  Fly     8 AIILETQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENITSRED 72
            |::..||:.|||.|::||||||||.|||||:|.|:.:..|:.:|...||||..|...:|:..::.
  Rat     4 AVVRRTQEALGKVIRRPPLTEKLLNKPPFRYLHDIITEVIRITGFMKGLYTDAEMKSDNVKDKDA 68

  Fly    73 KIRFLQKMIDATKLTTKLDLKVRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVVISH- 136
            ||.||||.||...:.:...|..:.::||||.|||.||||||.:.......|..|..|.:|:...
  Rat    69 KISFLQKAIDVVMMVSGEPLAAKPARIVAGHEPERTNELLQLIGKCCLSKLSSDEAVKRVLAGEK 133

  Fly   137 --SKTPLTLTKPPKETKNSSKNPSPAGKDEDAKRRKEKRISPQEQKLR------KVKEQVSRSTP 193
              |:..:..|...:|..|.|.      |:|:::.:||::.| .|.|.|      |.||::...:.
  Rat   134 GDSRGRVLRTSKAQEPDNKSV------KEEESRTQKEEKRS-SEVKERSSSAEHKQKEELKEDSK 191

  Fly   194 PTEKDKASQKKSKAPKD-----------------------------------ETKLSR------Q 217
            |.||::..:|..:|.:|                                   ||:..|      .
  Rat   192 PREKERDKEKAKEADRDRHREPDRDRNRDGEREKARARAKQDRDRNNKDRDRETERDRDRDRRSD 256

  Fly   218 NSKQKSPSPVKQKSKAKLQPSTESDNLSQSMSPVEE----------------GSTKPAA------ 260
            ..|:|.....:.:.|.|.:...:|.|...:..|..|                |::|.:.
  Rat   257 GGKEKERQKDRDRDKGKDRERRKSKNGEHTRDPDREKSRDADKSEKKADISVGASKSSTLKASKR 321

  Fly   261 -----------SESAPSKPEPEMVPPLKEKEAVVRPVQETPTAPPAEPESRKSSSRSRR-----S 309
                       |.::.:.|.||     ||::|..|..::..:   .:...||..:.|.:     .
  Rat   322 RSKNSLEGRRDSRASENNPSPE-----KERKASYRKAKKDHS---MKQLGRKEDNISAKILDSIV 378

  Fly   310 SGSHRQPEPNPIPNE------------SQSQPAVQSSETSSPPETNSGEAKREVPLTR------E 356
            ||.:.:|:......|            ::.:|||:....|  |....|||   ||.::      |
  Rat   379 SGLNDEPDQETTAPEIDDNSASLWRENAEPEPAVKQKGDS--PSDAEGEA---VPTSQDKLEVTE 438

  Fly   357 NSKEVNQRPRTSLRPPSARPASARPGAPRRRNVEIVLQPNDQIKMSGINVK---LETFGDLDDDG 418
            |::..|:.|.:..|.|  ||.||||..||.:..|...........||..|.   :::....::|.
  Rat   439 NAEVSNELPSSLRRIP--RPGSARPAPPRVKRQESTETLAGDRSGSGKTVSTVIIDSQNSDNEDD 501

  Fly   419 ENLVIIEDSAAHDIVEGGGDEPALEGQLDAQ---GRLVQQILETQKELVNQGAEVEPPPAQAGR- 479
            |..|:   .||..:.|....|....|.|:.:   |.||::||||:|:.  :..:..|.|.:..|
  Rat   502 EQFVV---EAAPQLSEIAEIEMVPSGDLEDEEKHGGLVKKILETKKDY--EKLQQSPKPGEKERS 561

  Fly   480 -----------QTSARQVNDVRDVVQKLTKSIGPLGKLLDCIPEDFDAMQLELTMWRDTYTQAST 533
                       ...::::..:|..:|.|.||..||||::|.|.||.||||.||.:|.....|.:.
  Rat   562 LIFESAWKKEKDIVSKEIEKLRVSIQTLCKSALPLGKIMDYIQEDVDAMQNELQLWHSENRQHAE 626

  Fly   534 ELKREQTLTASATEPLQHQLQQIQASIAEYRELIDESRHKILQNNARILKLM 585
            .|.:||::|.||.|||:.:|.:::..|.:.::.|...:..||:|..:|.|::
  Rat   627 ALSKEQSITDSAVEPLKAELSELEQQIKDQQDKICAVKANILKNEEKIQKMV 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT54	NP_650353.1	MIP-T3	9..119	CDD:463020	51/109 (47%)
		PHA03247	<146..395	CDD:223021	73/351 (21%)
		MIP-T3_C	444..588	CDD:465481	51/157 (32%)
Traf3ip1	XP_017452029.1	MIP-T3	5..117	CDD:463020	51/111 (46%)
		PTZ00121	<117..591	CDD:173412	105/500 (21%)
		U2AF_lg	191..>324	CDD:273727	19/132 (14%)
		MIP-T3_C	527..681	CDD:465481	49/154 (32%)