Protein Alignment IFT54 and dyf-11

DIOPT Version :10

• Sequence 1: NP_650353.1
• Gene: IFT54 / 41739
• FlyBaseID: FBgn0038221
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_508149.1
• Gene: dyf-11 / 180421
• WormBaseID: WBGene00001127
• Length: 535
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 155/596 - (26%)
• Similarity: 266/596 - (44%)
• Gaps: 98/596 - (16%)

  Fly    12 ETQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENITS----RED 72
            ||:::|.|.|:||.||::||.:|||:|::|:.||.||.:|.....:|.:|     |.|    :..
 Worm     5 ETREILEKVIQKPQLTDQLLSRPPFKFIVDIVSNVIKSTGYLKTDFTDDE-----IKSAGNDKNT 64

  Fly    73 KIRFLQKMIDATKLTTKLDLK-VRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVVISH 136
            |..||.|:|   |:.....|| |:.:||::|::.|.||::||.:.:.|..             .:
 Worm    65 KTAFLDKLI---KILDDGSLKNVKAAKIISGKDAEETNKMLQMLGTNATS-------------FN 113

  Fly   137 SKTPLTLTKPPKETKNSSKNPSPAGKDEDAKRRKEKRISPQEQKLRKVKEQVSRSTPPTEKDKAS 201
            |:......|..|:.|...|.     .||:.|...:||.|.:|....|.|.:..:|.    ::|..
 Worm   114 SRNGTGEEKKKKKVKKEDKK-----GDEEEKSTTKKRSSKKETHEEKEKSEKKKSA----EEKEK 169

  Fly   202 QKKSKAPKDETKLSRQNSKQKSPSPVKQKSKAKLQPSTESDNLSQSMSPVEEGSTKPAASESAPS 266
            :|||.:.|:..|.|.::|::.|....|:|.|.|              |..:|   ||..|:..||
 Worm   170 KKKSSSSKERHKSSDRSSEKSSEKSSKEKKKEK--------------STTDE---KPKKSKKDPS 217

  Fly   267 KPEPEMVPPLKEKEAVVRPVQETPTAPPAEPESRKSSSRSRRSSGSHRQPEPNPIPN---ESQSQ 328
            :..      .|.:::::....:.|..|        ::.........|...||..|.|   :..:|
 Worm   218 ERH------FKRQDSMIAVNGDAPDTP--------NNENGDEGYDDHEISEPTVISNMETDLSAQ 268

  Fly   329 PAVQSSETSSPPETNS---GEAKREV------PLTRENSKEVNQRPRTSLRPPSARPASARPGAP 384
            ..:.....:||.:|:.   ||:.|.:      ||.|..:.....||.||:..|..  |::||..|
 Worm   269 SLLIQQPVTSPLKTDDSGMGESPRMIKPEDRPPLIRPMTGAGGGRPMTSMGRPGT--AASRPAPP 331

  Fly   385 RRRNVEIVLQPNDQIKMSGINVKLETFGDL----DDDGENLVIIEDSAAHDIVEGGGDEPA-LEG 444
            :.:..:|...  |......:.:|.|...|.    .:|..|.::..|       |..||..| :|.
 Worm   332 KLKKKQIATV--DSTPQVVVELKSEIISDAPKVETEDDSNFIMEND-------EEDGDRTARIED 387

  Fly   445 QLDAQ--GRLVQQILETQKELVNQGA--EVEPPPAQAGRQTSARQVNDVRDVVQKLTKSIGPLGK 505
            .:|.:  |.|||:|:||:.|:.:.|.  :||...|.........::..:::.:|.||:|..||.:
 Worm   388 LVDEEDRGALVQKIMETKAEIEDGGGQDQVEESDADKIMTVEREKMKQLQEKLQDLTRSAYPLAR 452

  Fly   506 LLDCIPEDFDAMQLELTMWRDTYTQASTELKREQTLTASATEPLQHQLQQIQASIAEYRELIDES 570
            |.|...:|.::|..||..||....:...|.:.::......:..|.:.:..:|..|.:.:|.:.::
 Worm   453 LFDFANDDIESMIKELERWRSEQRRNEQEDQNKKAAGFGDSSRLYNIIANLQKEINDTKEELSKA 517

  Fly   571 RHKILQNNARI 581
            |.::|.|..||
 Worm   518 RGRVLNNEKRI 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT54	NP_650353.1	MIP-T3	9..119	CDD:463020	42/111 (38%)
		PHA03247	<146..395	CDD:223021	61/260 (23%)
		MIP-T3_C	444..588	CDD:465481	37/142 (26%)
dyf-11	NP_508149.1	MIP-T3	2..111	CDD:463020	43/113 (38%)
		dermokine	<301..>328	CDD:455732	9/28 (32%)
		MIP-T3_C	389..535	CDD:465481	37/140 (26%)