Protein Alignment IFT54 and IFT54

DIOPT Version :10

• Sequence 1: NP_650353.1
• Gene: IFT54 / 41739
• FlyBaseID: FBgn0038221
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_061504404.1
• Gene: IFT54 / 1281746
• VectorBaseID: AGAMI1_010253
• Length: 677
• Species: Anopheles gambiae
• Alignment Length: 693
• Identity: 266/693 - (38%)
• Similarity: 357/693 - (51%)
• Gaps: 129/693 - (18%)

  Fly     5 DLDAIILE-TQKVLGKYIKKPPLTEKLLKKPPFRFLMDVFSNFIKQSGTFDGLYTPEEQMFENIT 68
            :|||.:|: ||..|||::|:|.||||||:|||||||.|:....|::.|:.|||||.:|...:||.
Mosquito     4 ELDATVLKRTQSSLGKFVKRPALTEKLLRKPPFRFLHDIVHAIIREHGSLDGLYTADELNSDNIK 68

  Fly    69 SREDKIRFLQKMIDATKLTTKLDLKVRTSKIVAGQEPELTNELLQAMASVAEKNLEWDSIVDQVV 133
            .|:.|:.||||:||..||||..:||||.||||||.|||.|||||||:||:.|:.|....||...:
Mosquito    69 DRDSKMAFLQKLIDVVKLTTGRELKVRPSKIVAGLEPERTNELLQALASILEEKLSTTEIVRHYL 133

  Fly   134 ISHSKTPLTLTKPPKETKNSSKNPSPAGKDEDAKRRKEKRISPQEQKLRKVKEQVSRSTPPTEKD 198
               ...|.|..  ...:..|..|..|.......:.|:|.:.|.||:...|.||..:.:..|..||
Mosquito   134 ---GDNPTTTN--GVNSNGSGPNAGPETNGTKGETREEGKKSKQERVKEKPKENEATAVDPRRKD 193

  Fly   199 KASQKKSKAPKDETKLSRQNSKQKSPSPVKQKSKAKLQPSTESDNLSQSMSPVEEGSTKPAASES 263
            |..:.|.|    |...:....||...:..||.. .|:||:..:...|...|..:|.........|
Mosquito   194 KNGKVKEK----EVLKNGTTVKQVEKAKTKQNG-TKVQPNDSTKKKSDKPSKGKEKEKSVKRISS 253

  Fly   264 APSKPEPEMVPPLKEKEAVVRPVQETPTAPPAE--------PESRK------------------- 301
            .|.:|:|..||   |:   |.|.:..||....|        |||||
Mosquito   254 IPEEPQPPAVP---ER---VTPARPEPTTNGTESMVNGGNAPESRKRRDSIKEFGEPVTLSDANG 312

  Fly   302 -----------------SSSRSRRSS--------------------------------------G 311
                             |:|.|||||                                      |
Mosquito   313 EASGEEEHEKRRQQQPGSNSSSRRSSLKKQNSLTPSENNALSEMNQFNGLQSSLSRQDSNGALVG 377

  Fly   312 SHRQPEPNPIPNESQSQPAVQSSETSSPPETNSGEAKREVPLTRENSKEVNQRPRTSLRPPSARP 376
            ......|:.:...|:.:.|..:...::|.|:.|...|  .|:.|:.|.|...||||||||||.||
Mosquito   378 QDALAGPDDVAATSEQRMAEVTVTVAAPVESKSSAVK--PPMHRQQSVETVMRPRTSLRPPSVRP 440

  Fly   377 ASARPGAPRR--RNVEIVLQPNDQIKMSGINVKLETFGD--LDDDGENLVIIED--SAAHDIVEG 435
            .|||||||||  :|||::||||:..|:..||||:|.|..  ||||||||::|||  :.:..:|.|
Mosquito   441 PSARPGAPRRKEKNVEVILQPNETQKLGEINVKMEVFNSELLDDDGENLIVIEDPTTVSDGLVYG 505

  Fly   436 ------GG--DEPAL---EGQLDAQGRLVQQILETQKEL---------VNQGAEVEPPPAQAGRQ 480
                  ||  ||.||   ..|.:.||.|||||||||||.         :.:.|::|....|  ||
Mosquito   506 RAGEPPGGAADETALLQSAEQEEQQGHLVQQILETQKEFSTHTGTDSELLRKADMEWTAGQ--RQ 568

  Fly   481 TSARQVNDVRDVVQKLTKSIGPLGKLLDCIPEDFDAMQLELTMWRDTYTQASTELKREQTLTASA 545
            :||||:..:|:.:||||:|:.|||||:|.|.||.|:|:.||..|:..|||:..||.:|::.|.:|
Mosquito   569 SSARQMESLRESIQKLTRSVNPLGKLMDFIQEDIDSMERELASWQQIYTQSMVELNKERSATENA 633

  Fly   546 TEPLQHQLQQIQASIAEYRELIDESRHKILQNNARILKLMMEQ 588
            .|||:.||.||:.:|.|||::||.:|..||||.|:|.:|.|.:
Mosquito   634 IEPLKQQLSQIEVNIKEYRDMIDTTRANILQNEAKIERLYMTE 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT54	NP_650353.1	MIP-T3	9..119	CDD:463020	66/110 (60%)
		PHA03247	<146..395	CDD:223021	89/332 (27%)
		MIP-T3_C	444..588	CDD:465481	73/152 (48%)
IFT54	XP_061504404.1	None