Protein Alignment trx and MEA

DIOPT Version :10

• Sequence 1: NP_476769.1
• Gene: trx / 41737
• FlyBaseID: FBgn0003862
• Length: 3726
• Species: Drosophila melanogaster
• Sequence 2: NP_563658.1
• Gene: MEA / 839422
• AraportID: AT1G02580
• Length: 689
• Species: Arabidopsis thaliana
• Alignment Length: 814
• Identity: 156/814 - (19%)
• Similarity: 300/814 - (36%)
• Gaps: 240/814 - (29%)

  Fly  2962 IPAQTQQ--QQLQQAQMIHIPQQQQPLQQQQVQVQPSMPIITLAEAPVVQSQFVMEPQALEQQEL 3024
            :|.:..|  :|:::.:.:||.      ::.:::..||:    ...|...||..:.:|.|
plant    13 LPPELNQIKEQIEKERFLHIK------RKFELRYIPSV----ATHASHHQSFDLNQPAA------ 61

  Fly  3025 ANRVQHFSTSSSSSSSNCSLPTNVVNPMQQQAPSTTSSSTTRPTNRVLPMQQ---RQEPAP--LS 3084
                     ...:...|.||.:.:.||::..:.|:..:| ......||...|   .:|..|  |.
plant    62 ---------EDDNGGDNKSLLSRMQNPLRHFSASSDYNS-YEDQGYVLDEDQDYALEEDVPLFLD 116

  Fly  3085 NECPVVSSPTPPKPVEQPIIHQMTSASVSKCYAQKSTLPSPVYEAELKVSSVLESIVPDVTMDAI 3149
            .:.|::.|      |:.||:.:: ..|::..:.:.|.|             :.||       |::
plant   117 EDVPLLPS------VKLPIVEKL-PRSITWVFTKSSQL-------------MAES-------DSV 154

  Fly  3150 LEEQPVTESIYTEGLYEKNSPGESKTEQLLLQQQQREQLNQQ-------------LVNNGYLLDK 3201
            :.::.:   .|..|...:.|..|.:.:    :::..|::.::             .|...|.||.
plant   155 IGKRQI---YYLNGEALELSSEEDEED----EEEDEEEIKKEKCEFSEDVDRFIWTVGQDYGLDD 212

  Fly  3202 HTFQ---VEPMDTDV------YREEDLEEE--EDEDDDFSLKMATSA-----------------C 3238
            ...:   .:.::.||      |.|..|:.:  ..|..|.:.|..|:|                 |
plant   213 LVVRRALAKYLEVDVSDILERYNELKLKNDGTAGEASDLTSKTITTAFQDFADRRHCRRCMIFDC 277

  Fly  3239 NDHEMSDSEEPAVKDKISKILDNLTNDDCAD-------SIATAT-TMEVDASAGYQQMVEDVLAT 3295
            :.||..:.|..:.:|| |.:.::.....|::       |:..|. .|:.|.|...:.:|.|...|
plant   278 HMHEKYEPESRSSEDK-SSLFEDEDRQPCSEHCYLKVRSVTEADHVMDNDNSISNKIVVSDPNNT 341

  Fly  3296 TAAQSAPTEEFEGALETAAVEAAATYINEMADAHVLDLKQLQNGVELELRRRKEEQRTVSQEQEQ 3360
               ...|.|:   .|....:|   .:.....|..:..|:.|:..:|:....|:::|.|:|.:..:
plant   342 ---MWTPVEK---DLYLKGIE---IFGRNSCDVALNILRGLKTCLEIYNYMREQDQCTMSLDLNK 397

  Fly  3361 SKAAIVPTAAAPEPPQPIQEPKKMTGPHLLYEIQSEDGFTYKSSSITEIWEKVFEAVQVARRAHG 3425
            :                                      |.:.:.:|:         :|:|::.
plant   398 T--------------------------------------TQRHNQVTK---------KVSRKSS- 414

  Fly  3426 LTPLPEGPLADMGGIQMIGLKTNALKYLIEQLPGVEKCSKYTPKYHKRNGNVSTAANGAHGGNLG 3490
                           :.:..|:...|| ....|.::|.:....|::|.
plant   415 ---------------RSVRKKSRLRKY-ARYPPALKKTTSGEAKFYKH----------------- 446

  Fly  3491 GSSASAALSVSGGDSHGLLDYGSDQDELEENAYDCARCEPYSNRSE--YDMFSWL-----ASRHR 3548
             .:.....|..|.....|         ..||.     ||.|...|:  .:.|...     ...:|
plant   447 -YTPCTCKSKCGQQCPCL---------THENC-----CEKYCGCSKDCNNRFGGCNCAIGQCTNR 496

  Fly  3549 KQPIQVFVQPSDNELVPR------RGTGSNLPMAMKYRTLK---ETYKDYVGVFRSHIHGRGLYC 3604
            :.|.....:..|.:|...      .||....|:.::.:.::   :|.|..: :.:|.:||.|.:.
plant   497 QCPCFAANRECDPDLCRSCPLSCGDGTLGETPVQIQCKNMQFLLQTNKKIL-IGKSDVHGWGAFT 560

  Fly  3605 TKDIEAGEMVIEYAGELIRSTLTDKRERYYDSRGIGCYMFKIDDNLVVDATMRGNAARFINHCCE 3669
            ...::..|.:.||.||||.....::|.|..|..| ..|:|.::|.|.:||..:||..:|:||...
plant   561 WDSLKKNEYLGEYTGELITHDEANERGRIEDRIG-SSYLFTLNDQLEIDARRKGNEFKFLNHSAR 624

  Fly  3670 PNCYSKVVDILGHKHIIIFALRRIVQGEELTYDY 3703
            ||||:|::.:.|.:.|.:||.|.|.:||||.:||
plant   625 PNCYAKLMIVRGDQRIGLFAERAIEEGEELFFDY 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:413390
		PRK13914	<1006..>1224	CDD:237555
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134
		FYRN	1890..1937	CDD:461787
		FYRC	3388..3476	CDD:197781	11/87 (13%)
		SET_KMT2A_2B	3575..3726	CDD:380947	45/132 (34%)
MEA	NP_563658.1	preSET_CXC	485..515	CDD:408079	4/29 (14%)
		SET_EZH	544..660	CDD:380917	44/117 (38%)