DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trx and phf11

DIOPT Version :9

Sequence 1:	NP_476769.1	Gene:	trx / 41737	FlyBaseID:	FBgn0003862	Length:	3726	Species:	Drosophila melanogaster
Sequence 2:	XP_021334650.1	Gene:	phf11 / 569187	ZFINID:	ZDB-GENE-081104-417	Length:	531	Species:	Danio rerio

Alignment Length:	351	Identity:	78/351 - (22%)
Similarity:	126/351 - (35%)	Gaps:	94/351 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1736 MCLFCRKSGE-----GLSGEEARLLYCGHDCWVHTNCAMWSAEV-------FEEIDG-SLQNVHS 1787
            :|..|:.|.|     .||.:|        |...|.||.::|:.:       ::::.| .|::|..
Zfish    13 ICALCKTSDETETTGPLSSKE--------DISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKK 69

  Fly  1788 AVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCAFLTDKS-----MYCPAHAKNGNA 1847
            ...||:.::|..|...||||||.::.|...:|||||...|...:.|.|     :||.:|..|
Zfish    70 EQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPN--- 131

  Fly  1848 LKANGSPSVTYESNFEVSRPVYVELDRKRKKLIEPARVQFHIGSLEVRQLGAIVPRFSDSYEAVV 1912
                     ..|.|.|:...|.:.|          |.|:.|:.:.:..|......|...|.|.
Zfish   132 ---------PIEINDEIDNDVDLVL----------ASVEKHVPAEQHNQSTPDPERTRPSEEV-- 175

  Fly  1913 PINFLCSRLYWSSKEPWKIVEYTVRTTIQNSSSTLTALDV---GRNYTVDHTNPNSKEVQLGMAQ 1974
                         |.|.|.......|:.|.|..|.....:   .:.::.:|..|..|:.:
Zfish   176 -------------KTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKK----- 222

  Fly  1975 IARWHTSLARSEFLENGGTDWSGEFPNPNSCVPPDENTEEEPQQQADLLPPELKDAIFEDLPHEL 2039
                    .|.|:.:|.....:.....|....|.:..|..:|..... ||...:..       |.
Zfish   223 --------RRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTP-LPENTRSC-------EK 271

  Fly  2040 LD----GISMLDIFLYDDKTDLFAIS 2061
            |:    |.:..|   .||:||:.::|
Zfish   272 LNLSTTGAAADD---EDDETDIESVS 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:295381
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134	36/121 (30%)
		FYRN	1891..1935	CDD:283589	7/43 (16%)
		FYRC	3388..3476	CDD:197781
		SET	3590..3710	CDD:214614
phf11	XP_021334650.1	ePHD_PHF6_like	14..128	CDD:277143	36/121 (30%)
phf11	XP_021334650.1	Herpes_BLLF1	<228..445	CDD:330317	16/78 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810