|
Fly 2696 LETIVQNTVMSSQQFVSTA---MPGMLSQNAS---------FSATTTQVFQ-ASKIEPIVDLPAG 2747
::.|:.||:....|.:.:| .......|:. :.||..|.|| .:..|.:..|..|
Human 8 MQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIAEDGGQTPYEATLQQGFQYPATTEDLPPLTNG 72
Fly 2748 YVVLNNTGDASSAGTFLNAASVLQQQTQDDTTTQILQNANFQFQSV----PTSSGASTSMDY--- 2805
|. ::.||.:.||:..:..|....:...|.:| || ||
Human 73 YP---------------SSISVYETQTKYQSYNQYPNGSANGFGAVRNFSPT--------DYYHS 114
Fly 2806 ----TSPVMVTAK-IPPVTQIKRTNAQAKAAGISGVGKVPPQPQVVNKVLPTSIVTQQSQVQVKN 2865
|.|..:..| .|| :.||.|.|...|:|....:.:.::::..
Human 115 EIPNTRPHEILEKPSPP--------------------QPPPPPSVPQTVIPKKTGSPEIKLKITK 159
Fly 2866 S-----NLKQSQVKG------KAASGTGTTCGAPPSIASKPLQKKTNM-------IRPIHKLEVK 2912
: .|.:|.:.| :|:..|.: ...:.|..:||:|. .|..||:
Human 160 TIQNGRELFESSLCGDLLNEVQASEHTKS-----KHESRKEKRKKSNKHDSSRSEERKSHKI--- 216
Fly 2913 PKVMKPTPKVQNQNHSLLQQQQQQQPQLQQQIPA-VVVNQVPKVTIS------------------ 2958
||:........|:....:.::.:::|.|:::.|. .:::.||...:|
Human 217 PKLEPEEQNRPNERVDTVSEKPREEPVLKEEAPVQPILSSVPTTEVSTGVKFQVGDLVWSKVGTY 281
Fly 2959 ------------------------------------------QQRI--------------PAQTQ 2967
::|: .|..|
Human 282 PWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQ 346
Fly 2968 QQQLQQAQMIHIPQQQQPLQQQQVQVQPSMPIITLA-EAPVVQSQFV-MEPQALEQQELANRVQH 3030
.....:.|.|..|:.|:...|..:.:..:...:.:. |..:.|..|: ::.|..|....|.:
Human 347 ASNHSEKQKIRKPRPQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKK--- 408
Fly 3031 FSTSSSSSSSNCSLPTNVVNPMQQQ------APSTTSSSTTRPTNRVLPMQQRQEPAPLSNECPV 3089
|.:|.:.......|.:|:|...:| |.|.:|:...|.:.|.....:.:||.|:......
Human 409 -SVASKTEVKKTRRPRSVLNTQPEQTNAGEVASSLSSTEIRRHSQRRHTSAEEEEPPPVKIAWKT 472
Fly 3090 VSSPTPPKPVEQPIIHQMTSASVSKCYAQKSTLPSPVYEAELKVSSVLESIVPDVTMDAILEEQP 3154
.:: .|.:...|.....|..:.||.. ||| :|:..|. .:.:.|.|....:|.
Human 473 AAA---RKSLPASITMHKGSLDLQKCNM------SPV----VKIEQVF--ALQNATGDGKFIDQF 522
Fly 3155 VTESIYTEGLYEKNSPGESKTEQLLLQ-QQQREQLNQQLVNNGYLLDKHTFQVE----------- 3207
|.. |:|:..|........::|::. ..||.:...|.|::.......|..||
Human 523 VYS---TKGIGNKTEISVRGQDRLIISTPNQRNEKPTQSVSSPEATSGSTGSVEKKQQRRSIRTR 584
Fly 3208 ---PMDTDVYREEDLEEEEDEDDDFSLKMATSAC----NDHEMSDSEEPAVKDKISKILDNLTND 3265
...|:|..::.:::|:.| ::..||... ...|:|||.:|..|...:.....:|:.
Human 585 SESEKSTEVVPKKKIKKEQVE----TVPQATVKTGLQKGASEISDSCKPLKKRSRASTDVEMTSS 645
Fly 3266 ---DCADSIATATTMEVDASAGYQQMVEDVLATTAAQSAPTEEFEGALETAAVEAAATYINEMAD 3327
|.:||.:...: |...|:.:.|:...|| ||
Human 646 AYRDTSDSDSRGLS---DLQVGFGKQVDSPSAT------------------------------AD 677
Fly 3328 AHVLDLKQLQNGVELELRRR---KEEQRTVSQEQEQSKAAIVP---------------TAAAPEP 3374
|.|.|::.:.: .|.|| ..::.||.|..|.|..:::| .|:.|:.
Human 678 ADVSDVQSMDS----SLSRRGTGMSKKDTVCQICESSGDSLIPCEGECCKHFHLECLGLASLPDS 738
Fly 3375 PQPIQEPKKMTGPHLLY--EIQSED---------GFTYKSSSITEIWEKVFE------------A 3416
.....|.| ||.|..: ::..:| |..|..:.:.:....:|| |
Human 739 KFICMECK--TGQHPCFSCKVSGKDVKRCSVGACGKFYHEACVRKFPTAIFESKGFRCPQHCCSA 801
Fly 3417 VQVARRAHGLTPLPEG--------PLADMGGIQMIGLKTNAL-KYLIEQLPGVEKCSKYTPKYHK 3472
..:.:..|..: :| |:|...|...|...:..: .|:: .||.:: |
Human 802 CSMEKDIHKAS---KGRMMRCLRCPVAYHSGDACIAAGSMLVSSYIL-------ICSNHS----K 852
Fly 3473 RNGNVSTAANG----AHGGNLGGSSASAALSVSGGDSHGLLDYGSDQD----------------- 3516
|:.|.|....| ...|.:....:....|.....||.||:..:..:
Human 853 RSSNSSAVNVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRAELMKLPMIPSSSASKKKC 917
Fly 3517 -----------------------ELEENAYDCARCEPYSNRSEYDMFSWL--------------- 3543
|:.|..::|..|:. ..:..|....|:
Human 918 EKGGRLLCCESCPASFHPECLSIEMPEGCWNCNDCKA-GKKLHYKQIVWVKLGNYRWWPAEICNP 981
Fly 3544 ----------------------------------------------------------------- 3543
Human 982 RSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAK 1046
Fly 3544 ------ASRHRKQPIQ----------------------VFVQPSDNELVPR---RGTGSNLPMAM 3577
|.|..|:.:: |.:|.:|...:|| :....| |..:
Human 1047 RFQELKAQRESKEALEIEKNSRKPPPYKHIKANKVIGKVQIQVADLSEIPRCNCKPADEN-PCGL 1110
Fly 3578 KYRTL-------------------------KETYKDYVGVFRSHIHGRGLYCTKDIEAGEMVIEY 3617
:...| |..|.| ..:.::...|.||...:.|:.||.|.||
Human 1111 ESECLNRMLQYECHPQVCPAGDRCQNQCFTKRLYPD-AEIIKTERRGWGLRTKRSIKKGEFVNEY 1174
Fly 3618 AGELIRSTLTDKRE------RYYDSRGIGCYMFKIDDNLVVDATMRGNAARFINHCCEPNCYSKV 3676
.|||| |:.| |.:::.....||..:..:.::||..:||.:||:||.|.|||.::.
Human 1175 VGELI-----DEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQK 1234
Fly 3677 VDILGHKHIIIFALRRIVQGEELTYDYKFP-FEDEKIPCSCGSKRCRKYL 3725
..:.|...:.:|||..|..|.|||::|... ..:.:..|.||:..|..:|
Human 1235 WTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGNGRTECHCGADNCSGFL 1284
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