Protein Alignment trx and PHF11

DIOPT Version :10

• Sequence 1: NP_476769.1
• Gene: trx / 41737
• FlyBaseID: FBgn0003862
• Length: 3726
• Species: Drosophila melanogaster
• Sequence 2: NP_001035533.1
• Gene: PHF11 / 51131
• HGNCID: 17024
• Length: 331
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 67/294 - (22%)
• Similarity: 116/294 - (39%)
• Gaps: 67/294 - (22%)

  Fly  1702 STSQAESRSGVLDIPLEEVDDFGSCGIKMRLDTRMCLFCRKSGEGLSGEEARLLYC--GHDCWVH 1764
            |:.:|......|.:|.      |...:..:::.|.|..|.|.      .|..:||.  ..:...|
Human    16 SSPEARPAQEALLLPT------GVFQVAEKMEKRTCALCPKD------VEYNVLYFAQSENIAAH 68

  Fly  1765 TNCAMWSAEVFEEIDG---------SLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHY 1820
            .||.::|:.:.|..|.         .:::|...:.|||.:||..|..|||||||::::|.::||:
Human    69 ENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHF 133

  Fly  1821 PCARSIDCAFLTD--KSMY---CPAHAKNGNALKANGSPSVTYESNFEVSRPVYVELDRKRKKLI 1880
            .||:..|....:|  :.:|   |..||:         .|.:...:.|.     .|:..|.|||.:
Human   134 FCAKKDDAVPQSDGVRGIYKLLCQQHAQ---------FPIIAQSAKFS-----GVKRKRGRKKPL 184

  Fly  1881 EPARVQFHIGSLEVRQLGAIVPRFSDSY----EAVVPINFL--CSRLYWSSKEPWKIVEYTVRTT 1939
            ...    |:...|..:....:.:..:.:    :|.|.:.||  |       ||. .::.|.:...
Human   185 SGN----HVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKC-------KEA-GLLNYLLEEI 237

  Fly  1940 IQNSSSTLTALDVGRNYTVDHTNPNSKEVQLGMA 1973
            :....|....|       :|.|...|...::|.|
Human   238 LDKVHSIPEKL-------MDETTSESDYEEIGSA 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:413390
		PRK13914	<1006..>1224	CDD:237555
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134	35/119 (29%)
		FYRN	1890..1937	CDD:461787	9/52 (17%)
		FYRC	3388..3476	CDD:197781
		SET_KMT2A_2B	3575..3726	CDD:380947
PHF11	NP_001035533.1	ePHD_PHF11	45..159	CDD:277182	35/119 (29%)