DRSC/TRiP Functional Genomics Resources

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Protein Alignment trx and PHF11

DIOPT Version :9

Sequence 1:NP_476769.1 Gene:trx / 41737 FlyBaseID:FBgn0003862 Length:3726 Species:Drosophila melanogaster
Sequence 2:NP_001035533.1 Gene:PHF11 / 51131 HGNCID:17024 Length:331 Species:Homo sapiens


Alignment Length:294 Identity:67/294 - (22%)
Similarity:116/294 - (39%) Gaps:67/294 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly  1702 STSQAESRSGVLDIPLEEVDDFGSCGIKMRLDTRMCLFCRKSGEGLSGEEARLLYC--GHDCWVH 1764
            |:.:|......|.:|.      |...:..:::.|.|..|.|.      .|..:||.  ..:...|
Human    16 SSPEARPAQEALLLPT------GVFQVAEKMEKRTCALCPKD------VEYNVLYFAQSENIAAH 68

  Fly  1765 TNCAMWSAEVFEEIDG---------SLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHY 1820
            .||.::|:.:.|..|.         .:::|...:.|||.:||..|..|||||||::::|.::||:
Human    69 ENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHF 133

  Fly  1821 PCARSIDCAFLTD--KSMY---CPAHAKNGNALKANGSPSVTYESNFEVSRPVYVELDRKRKKLI 1880
            .||:..|....:|  :.:|   |..||:         .|.:...:.|.     .|:..|.|||.:
Human   134 FCAKKDDAVPQSDGVRGIYKLLCQQHAQ---------FPIIAQSAKFS-----GVKRKRGRKKPL 184

  Fly  1881 EPARVQFHIGSLEVRQLGAIVPRFSDSY----EAVVPINFL--CSRLYWSSKEPWKIVEYTVRTT 1939
            ...    |:...|..:....:.:..:.:    :|.|.:.||  |       ||. .::.|.:...
Human   185 SGN----HVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKC-------KEA-GLLNYLLEEI 237

  Fly  1940 IQNSSSTLTALDVGRNYTVDHTNPNSKEVQLGMA 1973
            :....|....|       :|.|...|...::|.|
Human   238 LDKVHSIPEKL-------MDETTSESDYEEIGSA 264

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trxNP_476769.1 NR_DBD_like 762..>856 CDD:295381
PHD1_KMT2A_like 1268..1344 CDD:276981
PHD 1346..1390 CDD:214584
PHD3_KMT2A_like 1423..1479 CDD:276983
ePHD_KMT2A_like 1737..1841 CDD:277134 35/119 (29%)
FYRN 1891..1935 CDD:283589 8/49 (16%)
FYRC 3388..3476 CDD:197781
SET 3590..3710 CDD:214614
PHF11NP_001035533.1 ePHD_PHF11 45..159 CDD:277182 35/119 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1084
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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