Protein Alignment trx and CG5098

DIOPT Version :10

• Sequence 1: NP_476769.1
• Gene: trx / 41737
• FlyBaseID: FBgn0003862
• Length: 3726
• Species: Drosophila melanogaster
• Sequence 2: NP_001261066.1
• Gene: CG5098 / 37063
• FlyBaseID: FBgn0034300
• Length: 1339
• Species: Drosophila melanogaster
• Alignment Length: 1380
• Identity: 288/1380 - (20%)
• Similarity: 424/1380 - (30%)
• Gaps: 458/1380 - (33%)

  Fly  2411 PAQPQLIAVSTNPDGTQQFIQIPQTMQATTT--------PTATYQTLQAT--NTD-----KKIML 2460
            |.||||..:|....|   .::.|.....:.|        |.|.|..:.|.  |.|     ..::.
  Fly    31 PRQPQLAHMSNERPG---MVRSPLAWHVSGTVSAQPPPPPDAIYNFMSANHKNLDHHHQMNPLLA 92

  Fly  2461 PLTAAGKPLKTV-----ATKAAQQAAVKQRQLKSGHQVKPIQAKLQPHPQQHQQQQQTQVQQPIT 2520
            |..:...|..::     :.::|.|...||         .|.|   |||  |.|||||:.:..|..
  Fly    93 PPYSGTLPFNSMDLSLQSARSAAQPLAKQ---------PPNQ---QPH--QTQQQQQSLIHAPNY 143

  Fly  2521 VMGQNL----------LQPQLLFQSSTQTQAPQIILPQAQPQNIISFVTGDGSQGQPLQYISIPT 2575
            ...|||          ||.|...:......|..:.|.|:..||          ||.|...:|  .
  Fly   144 PSIQNLTTNATPTSTQLQQQQQQEHLAAMAAAHVSLLQSSRQN----------QGAPSGNLS--N 196

  Fly  2576 AGEYK---PQPQPTATP-----TFLTTAPGAGAT-------YLQTDASGNLVLTTT--------- 2616
            .|:.:   |.|.||:..     |...::..:|:.       |:|: ...|..||..
  Fly   197 GGDCESLLPPPPPTSVSGNTNHTGSNSSSNSGSNNHIASPHYMQS-RDENFKLTQLKRSFEPDLS 260

  Fly  2617 ------------PSNSGLQMLTAQSLQAQ-----PQVIGTLIQPQTIQLGGGADGNQPGSNQQPL 2664
                        ||.|....|...::|.|     |..:....|.|           ||..|..|.
  Fly   261 GKNPQKEKDFGYPSASSASKLPTHNVQQQHANKKPSPLRNYHQQQ-----------QPPYNLTPK 314

  Fly  2665 ILGGTGGGSSGLEFATTSPQVILATQPMYYGLETIVQNTV----------------MSSQQFVST 2713
            ..|..         ...:||..||..|......|:..|.:                |...|..|.
  Fly   315 YNGPQ---------TPPTPQSPLAANPHQMLSPTMDYNQLHLHHQLNSSSGGSYQHMQQDQTQSQ 370

  Fly  2714 AMPGML---SQNASFSATTTQVFQASKIEPIVDLPAGYVVLNNTGDASSAGTFLNAASVLQQQTQ 2775
            :.|..|   :|:|     |:|......:.|:  |.:|.... ...|||...|    ||..|.||.
  Fly   371 SHPQHLHYHNQHA-----TSQTAPPPLLPPL--LTSGQFHA-QPQDASQQQT----ASSSQHQTH 423

  Fly  2776 DDTTTQILQNANFQFQSVPTSSGASTSMDYTSPVMVTAKIPPVTQIKRTNAQAKAAGISGVGKVP 2840
            ...|.| |.|.:...:..|.|.                :.|.:|.:...|::......:.|.:.|
  Fly   424 HSRTAQ-LTNLDQAVKHKPESE----------------EQPVITDLSYRNSETDKTAANPVPEAP 471

  Fly  2841 PQPQVVNKVLPTSIVTQQSQVQVKNSNLKQSQVKGKAASGTGTTC--GAPPSIASKPL--QKKTN 2901
            ..|     .|.||  .::|.....||:..:.:.|.||:.....|.  .||....|||.  |:..|
  Fly   472 ESP-----YLTTS--NEESLESNSNSSNSRKRRKRKASMVMRVTPNENAPEGENSKPQHPQQAAN 529

  Fly  2902 MIRPIHKLEVKPKVMKPTPKVQNQNHSLLQQQQQQQPQLQQQ-----IPAVVV------------ 2949
            :     .....||........:.|..|..:|.|.:..:..|:     .||...
  Fly   530 L-----NNSCSPKKSPKNGGGEFQPFSTQKQSQTENEKTTQENGRGGSPAPAENNSNSNSSTLYN 589

  Fly  2950 -NQVPKVTISQQRIPAQTQQQQLQQAQMIHIPQQQQPLQQQQVQVQPSMPIITLAEAPVVQSQFV 3013
             |:.||         .:.|:|.|.|..:....:.||..:..:....|:||      .|..||.
  Fly   590 DNENPK---------TKKQRQALLQRNLTEQHRMQQDDEPPKNHTSPAMP------PPSPQSN-- 637

  Fly  3014 MEPQALEQQELANRVQHFSTSSSSSSSNCSLPTNVVNPMQQQAPSTTSSSTTRPTNRVLPMQQRQ 3078
                              |:|||||||:.               :|.||.::...|.:
  Fly   638 ------------------SSSSSSSSSSA---------------NTHSSQSSHAVNNI------- 662

  Fly  3079 EPAPLSNECPVVSSPTPPKPVEQPIIHQMTSASVSKCYAQKSTLPSPVYEAELKVSSVLESIVPD 3143
             |.|..|......:|..|..|||..|....:.||.:|..::....:.|..|.           ||
  Fly   663 -PKPEINNKATTDTPASPALVEQGDIDAKPAVSVHECDEEEEPAVNKVSPAH-----------PD 715

  Fly  3144 VTMDAILEEQPVTESIYTEGLYEKNSPGESKTEQLLLQQQQREQLNQQLVNNGYLLDKHTFQVEP 3208
            ....|.:...|.|||      .:|:||.                .|.:....|.:.||    :|.
  Fly   716 PPTTAAVAAPPATES------PKKSSPA----------------ANSESCPFGEVEDK----LEQ 754

  Fly  3209 MDTDVYREEDLEEEEDEDDDFSLKMATSACNDHEMSDSEEPAVKDKISKILDNLTNDDCADSIAT 3273
            |...:       |||.|                .:|..|:|| ::..:.:..|||.....|...|
  Fly   755 MFAGI-------EEETE----------------RISSPEKPA-EESAAMVAHNLTAQLALDPSKT 795

  Fly  3274 ATTMEVDASAGYQQMVEDVLATTAAQSAPTEEFEGALETAAVEAAATYINEMADAHVLDLKQLQN 3338
                 :|..|..|   ..|||..|....||.|.......||:::.                 :.:
  Fly   796 -----LDTPAENQ---TSVLAVLAPNQTPTPEIRPVATKAAMKST-----------------MPS 835

  Fly  3339 GVELEL-RRRKEEQRTVSQEQEQSKAAIVPTAAAPEPPQP---------------IQEP------ 3381
            .|...: :.|......|:.:..:|...:...|.||..|.|               |.:|
  Fly   836 PVHSPIPQSRSTSTPLVAGDDSKSNTPVPAKAPAPRRPPPRRLSMGMDASLLRFMIDDPPAKKPG 900

  Fly  3382 --KKMTGPHLLYEIQSEDGFTYKSSSITEIWEKVFEAVQVARRAHGLTPLP-EGPLADMGGIQMI 3443
              ||:|     .|...||.....:|:..   .....|.|::..|......| .|......|::
  Fly   901 RKKKVT-----KEPDFEDDDKPSTSAAA---AAALAARQLSEAASATKSKPAAGAKKKNAGVK-- 955

  Fly  3444 GLKTNALKYLIEQLPGVEKCSKYTPKYHKRNGNVSTAANGAHGGNLGGSSASAAL---------- 3498
            |.|.:|.|       |..|.:|...|...|....:|..:.......||.|.....
  Fly   956 GKKGSAGK-------GNAKNAKQNGKKSARKPAFTTDEDSTPAPTNGGGSVPELRFKSPFILIKP 1013

  Fly  3499 --SVSGGDSHGLLDYGSDQDELEE-----------------NAYD---------CARCE------ 3529
              |||..::|...|....|.::::                 |.||         |..|:
  Fly  1014 DGSVSIKNTHSAEDVNEKQTKVKKAPHERKNLRGMHSSTLSNRYDADTTDSTWICVFCKRGPHKL 1078

  Fly  3530 -------PYSNRSEYDMFSWLASRHRKQPIQ-VFVQPSDNE-LVPRRGTGSNLP----------- 3574
                   ||...|:.|.:.........|.|. :||.....| :|  :|...|||
  Fly  1079 GLGDLFGPYLVTSDCDEYRAAVQTPGAQDIDGMFVNKRRREDMV--KGQERNLPAVPATLANIMQ 1141

  Fly  3575 ---MAMKYRTLKETY 3586
               ::|..|..|:|:
  Fly  1142 APKISMHKRKRKQTH 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:413390
		PRK13914	<1006..>1224	CDD:237555
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134
		FYRN	1890..1937	CDD:461787
		FYRC	3388..3476	CDD:197781	19/88 (22%)
		SET_KMT2A_2B	3575..3726	CDD:380947	4/12 (33%)
CG5098	NP_001261066.1	PHD_SF	1068..1284	CDD:473978	20/91 (22%)