DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trx and Phf7

DIOPT Version :9

Sequence 1:	NP_476769.1	Gene:	trx / 41737	FlyBaseID:	FBgn0003862	Length:	3726	Species:	Drosophila melanogaster
Sequence 2:	NP_001012211.1	Gene:	Phf7 / 364510	RGDID:	1308638	Length:	380	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	69/352 - (19%)
Similarity:	115/352 - (32%)	Gaps:	96/352 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1736 MCLFC-------RKSGEGLSGEEARLLYCGHDCWVHTNCAMWSAEVFEE------IDGSL-QNVH 1786
            :||.|       .|.||.|..:..        | ||..|.:.|:::.::      :.|.: :::.
  Rat    32 VCLLCFQEPGDPEKLGEFLQKDNL--------C-VHYFCLILSSKLPQKGQPNRGLHGFMPEDIK 87

  Fly  1787 SAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDC--AFLTDKSMYCPAHAKNGNALK 1849
            ...||.....|.||..:||.:.|....|.:::|.||.:...|  .|..:...||..|....|..:
  Rat    88 KEAARASRKVCFVCKRKGAAIRCQKDQCVQNFHLPCGQERGCLSQFFGEYKSYCGKHRPTQNIHQ 152

  Fly  1850 ANGSPS-------VTYESNFEVSRPVYVELDRKRKKLIEPA---------------RVQFHIGSL 1892
            .:...|       ::..|...:..|...:....||.:.:.|               |.:|   ..
  Rat   153 RSFGESCVLCCEDLSRASVENIRSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEF---PQ 214

  Fly  1893 EVRQLGAIVPRFSDSYEAVVPINFLCSRLYWSSKEPWKIVEYTVRTTIQNSSSTLTALDVGRNYT 1957
            |:.::|..:|....::|.                ||....|...|  .|:..:.:...:.||:..
  Rat   215 EMLRMGIHIPDRDAAWEL----------------EPGAFSELYQR--YQHCDAPICLYEQGRDSF 261

  Fly  1958 VDHTNPNSKEVQLGMAQIARWHTSLARSEFLENGGTDWSGEFPNP-----NSCVPP------DEN 2011
            .|.               .||...|..:........|.|...||.     |.|:|.      .||
  Rat   262 EDE---------------GRWRLILCATCGSHGTHRDCSSLRPNSKKWECNECLPASTEDSVSEN 311

  Fly  2012 TEEEPQQQADLLP--PELKDAIFEDLP 2036
            ..:.|...:...|  |.|:....|:.|
  Rat   312 LGDTPCCSSTFCPHEPFLRATSLEENP 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:295381
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134	29/119 (24%)
		FYRN	1891..1935	CDD:283589	7/43 (16%)
		FYRC	3388..3476	CDD:197781
		SET	3590..3710	CDD:214614
Phf7	NP_001012211.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		ePHD_PHF7_G2E3_like	33..144	CDD:277139	29/119 (24%)
		PHD_PHF7_G2E3_like	246..299	CDD:276971	11/67 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810