DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trx and phf6

DIOPT Version :9

Sequence 1:	NP_476769.1	Gene:	trx / 41737	FlyBaseID:	FBgn0003862	Length:	3726	Species:	Drosophila melanogaster
Sequence 2:	XP_021336655.1	Gene:	phf6 / 327070	ZFINID:	ZDB-GENE-030131-5278	Length:	376	Species:	Danio rerio

Alignment Length:	174	Identity:	50/174 - (28%)
Similarity:	76/174 - (43%)	Gaps:	36/174 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1727 GIKMRLDTRMCLFCRKSGEGLSGE----EARLLYCGHDCWVHTNCAMWSAEVFEEIDG-SLQNVH 1786
            |...||  |.|.|||.:.:...|:    |:..:...|.|.:.::..:.|....|.|.| |:::|.
Zfish     7 GASARL--RKCAFCRTNRDKECGQLLVAESHRVAAHHKCMLFSSALVTSHSDSENIGGFSIEDVK 69

  Fly  1787 SAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCA------------------RSIDCAFLTD 1833
            ..:.||..:.||.|...|||:||:|::|...|||.||                  :.:.......
Zfish    70 KEIKRGNKLMCTSCHRPGATIGCDVKTCRRTYHYYCALWDKAQTKENPSQGIYLRKQLQIGLEPG 134

  Fly  1834 KSMYCPAH---AKNGN----ALKANGSPSVTYES----NFEVSR 1866
            ||:||..|   :::|:    .:.||.|.|....|    .||.||
Zfish   135 KSVYCRKHRDASQDGSDDEQGVAANDSDSSPPRSRGRGRFEKSR 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:295381
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134	35/126 (28%)
		FYRN	1891..1935	CDD:283589
		FYRC	3388..3476	CDD:197781
		SET	3590..3710	CDD:214614
phf6	XP_021336655.1	PHD_SF	15..142	CDD:328929	35/126 (28%)
phf6	XP_021336655.1	ePHD2_PHF6	223..340	CDD:277181
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810