DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment trx and Phf11d

DIOPT Version :9

Sequence 1:	NP_476769.1	Gene:	trx / 41737	FlyBaseID:	FBgn0003862	Length:	3726	Species:	Drosophila melanogaster
Sequence 2:	NP_950180.3	Gene:	Phf11d / 219132	MGIID:	1277133	Length:	320	Species:	Mus musculus

Alignment Length:	351	Identity:	66/351 - (18%)
Similarity:	126/351 - (35%)	Gaps:	109/351 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1724 GSCGIKMRLDTRMCLFCRKSGEGLSGEEARLLYCGHDCW------------VHTNCAMWSAEVFE 1776
            |...|..:::.|.|..|.:               ||: |            .|.||.::|:.:.|
Mouse    15 GDSPIIEKMEKRTCALCPE---------------GHE-WSQIYFSPSGNIVAHENCLLYSSGLVE 63

  Fly  1777 ----EIDGSLQN-----VHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCAFLT 1832
                ::..:::|     |...:.|||.:||:.|...||||||::..|.:.|||.||:........
Mouse    64 CETLDLRNTIRNFDVKSVKKEIWRGRRLKCSFCNKGGATVGCDLWFCKKSYHYVCAKKDQAILQV 128

  Fly  1833 DKS-----MYCPAHA-KNGNALKANGSPSVTYE-------SNFEVSRPVYVELDRKRKKLIE--- 1881
            |.:     ::||.|: :...|.::...||:..:       |:...::|..::....::.:.|
Mouse   129 DGNHGTYKLFCPEHSPEQEEATESADDPSMKKKRGKNKRLSSGPPAQPKTMKCSNAKRHMTEEPH 193

  Fly  1882 ---PARVQF-----------------HIGSLEVRQLGAIVPRFSD------SYEAVVPINFLCSR 1920
               .|.|:.                 ||    :..:.::..|..|      .||.:..:.|.|.
Mouse   194 GHTDAAVKSPFLKKCQEAGLLTELFEHI----LENMDSVHGRLVDETASESDYEGIETLLFDCG- 253

  Fly  1921 LYWSSKEPWKIVEYTVRTTIQNSSSTLTALDVGRNYTVDHTNPNSKEVQLGMAQIARWHTSLARS 1985
                          ..:.|::.....:.:       .........::::..:..:|....||.
Mouse   254 --------------LFKDTLRKFQEVIKS-------KACEWEERQRQMKQQLEALADLQQSLC-- 295

  Fly  1986 EFLENGGTDWSGEFPNPNSCVPPDEN 2011
            .|.|||..|.|..  ...|.:||:::
Mouse   296 SFQENGDLDCSSS--TSGSLLPPEDH 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:295381
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134	33/129 (26%)
		FYRN	1891..1935	CDD:283589	6/49 (12%)
		FYRC	3388..3476	CDD:197781
		SET	3590..3710	CDD:214614
Phf11d	NP_950180.3	PHD_SF	28..142	CDD:304600	33/129 (26%)
Phf11d	NP_950180.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..196		6/50 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910