Protein Alignment trx and set-15

DIOPT Version :9

• Sequence 1: NP_476769.1
• Gene: trx / 41737
• FlyBaseID: FBgn0003862
• Length: 3726
• Species: Drosophila melanogaster
• Sequence 2: NP_001370771.1
• Gene: set-15 / 187813
• WormBaseID: WBGene00020006
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 115/619 - (18%)
• Similarity: 201/619 - (32%)
• Gaps: 199/619 - (32%)

  Fly  3229 FSLKMATSACNDHEMSDSEEPAVKDKI----SKILDN-----LTNDDCADSIATATTMEVDASAG 3284
            |..:..||..|       |:||.:.|.    ||.|:|     :..|....|...||
 Worm    21 FRKRSVTSLAN-------EQPAKRSKTEGSDSKKLNNQMKRLMAKDPKKLSFNEAT--------- 69

  Fly  3285 YQQMVEDVLATTAA----QSAPTEEFEGALETAAVEAAATYINEMADAHVLDLKQLQNGVELELR 3345
               ::.::|.|...    :..|..:..|||..:.|:    :.|:    ...:.|.:::|
 Worm    70 ---LLSELLTTCCTVERKKVIPKRKGGGALRKSPVD----FQND----ENRNTKPIKSG------ 117

  Fly  3346 RRKEEQRTVSQEQEQSKAAIVPTAAAPEPPQPIQEPKKMTGPHLLYEIQSEDGFTYKSSSITEIW 3410
             ||::...:.|..::.|.|             .:...::....::..::.:...| |:|..||..
 Worm   118 -RKKKDNLLEQASKKDKIA-------------AKYRNEIFAHSIIANLEIKKILT-KTSKATEKD 167

  Fly  3411 EKVFEAVQVARRAHGLTPLPE------------------GPLADMGGIQMIGLKTNALKYLIEQL 3457
            .|:|...:.:.| :.:...||                  ..:|||....|      |...|:..:
 Worm   168 LKLFLKAECSVR-NAIKSDPELDGFYVRTCGKLINKTVLNTMADMMDNHM------ATTRLLWNM 225

  Fly  3458 PGVEKCSKYTPKYHKRNGNVSTAANGAH---------GGNLGGSSASAALSVSGGDSHGLLDYG- 3512
            |..|    :...:|::  .|..|.|.::         ...|...|.|....:. |::|..:..|
 Worm   226 PRHE----FPVDFHEK--FVDFALNVSYTPPKKRIFVEKKLFEKSISTFTDIP-GETHRTISLGN 283

  Fly  3513 -----------------------SDQDELEENAYDCARCEPYS-----NRSEYDMFSWLASRHRK 3549
                                   :::.|...|...|..|...|     |..:...|.......::
 Worm   284 TFVYKYTERNVVDVEKYPELHALTEEAERPNNVIRCECCSSGSIKKCWNNPDCFCFQMNLKLRKE 348

  Fly  3550 QPIQVFVQPSDNELVPRRGTGSNLPMAMKYRTLKETYKDYVG----------------------- 3591
            |      .|.:|:|:....|..  |:.::.|   ..:.|.:|
 Worm   349 Q------DPKNNKLLTDFSTFD--PVFIRER---NHFFDTIGFACSENCACGGKCTNNITLLPEK 402

  Fly  3592 ------VFR-SHIHGRGLYCTKDIEAGEMVIEYAGELIRSTLTDKRERYY--------------- 3634
                  ::| :.|.|..:.....|.||..|:|:.|||:...:.|..::.|
 Worm   403 NINKFEIYRKNEIMGFAIRTLNSIPAGTPVMEFTGELMDFDILDNIDQDYAFEIVNEAHNLHETL 467

  Fly  3635 ---DSRGIGCYMFKIDDNLV----VDATMRGNAARFINHCCEPNCYSKVVDILG----HKHIIIF 3688
               :.|....:...:...|.    |:....||.||...|.|:||.....|...|    |..:::.
 Worm   468 PNFNKRWSENFKSSLKKQLARPWFVNPKRIGNVARICCHSCQPNMAMVRVFQKGFSPAHCKLLLV 532

  Fly  3689 ALRRIVQGEELTYDYKFPFEDE-KIPCSCGSKRC 3721
            .|..|..|.|||:||...:.:| |..|.|....|
 Worm   533 TLEDIFPGVELTFDYGPGYLNELKGGCLCERIGC 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:295381
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134
		FYRN	1891..1935	CDD:283589
		FYRC	3388..3476	CDD:197781	19/105 (18%)
		SET	3590..3710	CDD:214614	36/175 (21%)
set-15	NP_001370771.1	SET	405..554	CDD:214614	35/148 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165856
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840