DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trx and set-13

DIOPT Version :9

Sequence 1:	NP_476769.1	Gene:	trx / 41737	FlyBaseID:	FBgn0003862	Length:	3726	Species:	Drosophila melanogaster
Sequence 2:	NP_494371.1	Gene:	set-13 / 173626	WormBaseID:	WBGene00019690	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	180	Identity:	44/180 - (24%)
Similarity:	77/180 - (42%)	Gaps:	46/180 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  3582 LKETYKDYVGVFR-SHIHGRG--LYCTKDIEAGEMVIEYAGEL-----IRSTLTDKRERY----Y 3634
            |::..:|....|: :...|:|  :|..:.|:.|..|:|::||:     |:|..  ..|:|    |
Worm   191 LQDICEDPAKKFKITRTDGKGFCVYSARVIKKGSPVLEFSGEITDYLAIKSNA--DIEQYSIMLY 253

  Fly  3635 DSRGIGCYMFKIDDNLV----------------VDATMRGNAARFINHCCEPNCYSKVVDILGH- 3682
            ::....|..|..::||.                ::...|||.|||.:|.|:.|..      ||.
Worm   254 NNETKLCDFFSKEENLSSKYKKILWSAYRSKAWINPLNRGNCARFFSHGCKANME------LGRV 312

  Fly  3683 ---------KHIIIFALRRIVQGEELTYDYKFPFEDEKIPCSCGSKRCRK 3723
                     ..|::||...|..|.|||::|...:::..:...|..:.|:|
Worm   313 FQGGFSPADMKIVLFAKEIIKPGTELTFNYGPSYKEIFLGNKCLCEACKK 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trx	NP_476769.1	NR_DBD_like	762..>856	CDD:295381
		PHD1_KMT2A_like	1268..1344	CDD:276981
		PHD	1346..1390	CDD:214584
		PHD3_KMT2A_like	1423..1479	CDD:276983
		ePHD_KMT2A_like	1737..1841	CDD:277134
		FYRN	1891..1935	CDD:283589
		FYRC	3388..3476	CDD:197781
		SET	3590..3710	CDD:214614	39/157 (25%)
set-13	NP_494371.1	SET	200..348	CDD:214614	39/155 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840