|
Fly 13 SINRKRISVLQLEDDAANPAEPQQPAPESQQPSGSGSGS------SAAREKGNNCDNDEDDNAPG 71
||..|...|..:|..:.....| .|:...|:.|..|.|| :|:|::|:....|:.....|
Mosquito 171 SIAAKSAMVAAVEASSTRARAP-PPSTAQQRVSSEGGGSKALTATAASRKQGSRMLPDDKREERG 234
Fly 72 GA---------SISGNTASS------SAGSGNSGNGSSSGSS-TGSGSSGSGSTNGGSVNGGTHH 120
.. |.|||..|| |....:|.:.|||.|| |.:..|.:.||.|.:.| ||
Mosquito 235 RTMHTKARKRRSSSGNDGSSAGRTKKSVSESDSSSASSSFSSCTSNSDSDTSSTAGDNSN---HH 296
Fly 121 KSAANLDKEAVTKDQNGDGDKTRGNVSSA-PSGKLSAAASGK-----ALSKSSRTFSASTSVTS- 178
......|| .|...|.|...|...|:| .|| ||.|:|| ...|:|||.::|:|...
Mosquito 297 HQQQQDDK---AKQTVGGGRHARTAASAAVASG--SAIAAGKKQKILKRKKASRTATSSSSDEED 356
Fly 179 -----SGRS---SGSSPDGNSGASSDGASS-----GISCGKSTAKS-----------------TE 213
|||| ||::...|...|||.:|| ..:..::.||| |:
Mosquito 357 EEDLPSGRSGSKSGTANRTNEFTSSDTSSSDEDGKAFAAMRTKAKSLQSTKGSGKDGNGLLTLTD 421
Fly 214 ASSGKL------------AKTTGA---------------------GTCSS--------------- 230
.|:|.| ||..|| |:|||
Mosquito 422 GSAGGLLLNRPPLSTSTPAKQHGAFPPTLGGGMSSAGDGGLTAEGGSCSSDNELPALVSAAIRRV 486
Fly 231 -----AKSSKASSGTTSEATTSGLSGACLKALFVAT---------PATSTGLACALVSPGGSSQG 281
|:|.:..|..|.:.|:|.|....:|...:.| ||..:|.|.. |.||...|
Mosquito 487 ESGSDAESIRGLSAPTQQYTSSLLRDFVVKTQMLGTVGGGGAGAMPAGVSGSAAN--SAGGGGGG 549
Fly 282 GTFPISAALLRARKNSNKKFKNLNLARGEVMLPSTSKLKQLNSPVVDNPSPSPPIASGSTPSVEG 346
|..|.|::...:...|:.. .|:|.:::...|.:.:..|.| |
Mosquito 550 GGSPSSSSSSSSSSGSSSS-------------SSSSSMEEGADPAIGSAGPGP-----------G 590
Fly 347 GIGVGGVVSPGEDAALKRVLTEMPNEVARDPSPSSC---TAAANGAASGKGSASNGP-PAMASSG 407
|.|.|||.:...| ::::.||.| |.....|:|. |...||..:|....::.| ||.|...
Mosquito 591 GGGGGGVAAFELD--VRKIKTESP--VPSTLPPASVGRNTPLVNGLTTGGMKTTDLPVPAPAPKR 651
Fly 408 DGSSPKSG--ADTGPSTSSTTAKQKKTVTFRNVLETSDDKSVV------------KRFYNPDIRI 458
.|..|||. |...|..::......::||...|.| |.|..:: |......:|.
Mosquito 652 RGRPPKSSLQAAPAPPPAARPTGSSRSVTIPTVSE-SPDSGILSTHSSTGSPKTDKTRSASHLRS 715
Fly 459 PIVSIMKKDSLNRPLNYSRGGECIVRPSILSKILNKNSNIDKLNSLKFRSAGASSSSSNQESGSS 523
.:.:.....|..|..:.:||. ..|..|.||:........||:.....||:.|.|.....::
Mosquito 716 TVGATGSSTSSRRSKSEARGS----ASSASSAILSAGGAAYAANSVLPAPPGAAGSGSRTSGAAA 776
Fly 524 S----------NVFGLSRAFGAPMDEDDEGGVTFRRNDSPEDQNNAEDDEMDDDDDDEEAEEDDE 578
| |.:...|....|. .|:.:......:.|.....:.|.....
Mosquito 777 SSYALTSCLDRNTYATERVLYPPR--------------GPKKRGVGRPPKKDTAAHQQPAGAGRG 827
Fly 579 NEDDNDEAVSEKSAETEKSAGADERDPDEKQLVMDSHFVLPK----RSTRSSRIIKPNKRLL-EE 638
...::..|.|::.|| |..||..:::.:...|..|: :|......|..:|||. :.
Mosquito 828 GPANDPTARSQQQAE-------DRLDPHWQKIDISKKFHEPRLSGYKSDGGHSTICCSKRLASQS 885
Fly 639 GAISTKKPLSLGDSKGKNVFGTSSSSAGSTASTFSASTNLKLGKETFFNFGTLKPNSSAAGNFVL 703
|.|| :..|..:||..|..|.:.: :|..
Mosquito 886 GYIS-------------DYGGVGASSGRSRLSGYKS-------------------------DFSS 912
Fly 704 RQPRLQFQADNQQATFTAPKACPTSPSAIPKPANSLATSSFGSLASTNSSTVTPTPSACSICSAV 768
|..|...:|...::.:...|:|... |.||
Mosquito 913 RSRRSCSRAGGYRSDYGRAKSCGYR-------------------------------SDCS----- 941
Fly 769 VSSKEVTQARKYGVVACDVCRKFFSKMTKKSISANSSTANTSSGSQQYLQCKGNEGSPCSIHSAK 833
|:.|| .|.|| .:|.|.::..:......:|...|...|..|....::|.
Mosquito 942 ------TRHRK------QVRRK-----RRKKIGSHQQSQQQQHHNQHDHQHHNNNLSDRKNYNAS 989
Fly 834 SQLKNFKKFYKDRCTACWLKKCMISFQLPAAHRSRLSAILPPGMRGEAAAREEKSA-----ELLS 893
|. |.......||| |::.
Mosquito 990 SD-------------------------------------------GGGGGGSTKSASVGELEIMF 1011
Fly 894 PTGSLRFTSTASSSSPSVVASTSVKWKSSGDSTSALTSIKPNPLAENNVTFGSTPLLRPAILENP 958
..| |...||:...|.|..:||| .||.:|..:|.: ..:.|..|:..
Mosquito 1012 MAG-LTLGSTSDEDSSSTSSSTS---SSSAESRESLFT------DHSGVDRGANS---------- 1056
Fly 959 LFLKISNAADQKLAAAEA----ISPSLTKKNSKQEKEKVKESEQSEKLLSPTQAGTKKSGAAEAQ 1019
|:.||:...|... .:.:.||.|:|..:...|. :|.:...|..|||:|
Mosquito 1057 -----SSGADKVKRATSGRGRKANVATTKPNAKLPRTPRKP--------TPPKTVAKGRGAAKA- 1107
Fly 1020 VEEVQPQKEEAPQTSTTTQPSASNGASHGVPQAELAGETNATGDTLKRQRIDLKGPRVKHVCRSA 1084
.:...|.::|..:...:|.|.||
Mosquito 1108 ------PRGRPPSSTTIDRRRKANHAKHG------------------------------------ 1130
Fly 1085 SIVLGQPLATFGEDQQPEDAADM--QQEIAAPVPSAIMEPSPEKP--------THIVTDENDNCA 1139
...|.:..||:..|:.|:: ::.....|.:..::|:|:.| |..|..:..:.|
Mosquito 1131 ----SNKLDSDDEDEDEEEEAELVVKRRFGDRVRTKPLQPAPKDPPTKPSIAATASVALKQKSSA 1191
Fly 1140 SCKT-----SPVGDESKPSKSSGSAQAEVKKA-TALGKEGTASAAGGSSAKVTTRN--AAVASNL 1196
..|. .|.|.:.:|.::..:|.|..:.| ..||......|...|:|.|...| ..|.:::
Mosquito 1192 LVKKPGQRGRPPGVKKQPGRTGSTATAAAQPAGKTLGSLDVLLAPKNSTAPVLPVNNFDRVVASM 1256
Fly 1197 IVAASKKQRNGDIATSSSVTQSSNQTQGRKTKEHRQQRTLISIDFWENYDPAEVCQTGFGLIVTE 1261
..::|.||:.| ||...:||..| ..:.
Mosquito 1257 SGSSSGKQQPG----SSEAKKSSIYT-----------------------------------FSST 1282
Fly 1262 TVAQR---ALCFLCGSTGLDPLIFCACCCEPYHQYCVQDEYNLKHGSFEDTTLMGSLLETTVNAS 1323
|||.: |...|.|:...| .:.:|....|.|| ...
Mosquito 1283 TVAPKNAFAAFLLRGAAADD-------------------------AAKDDAEEGGRLL----GVK 1318
Fly 1324 TGPSSSLNQLTQRLNWLCPRCTVCYTCNMSSGSKVKCQKCQKNYHSTCLG---TSKRLLG--ADR 1383
..|.|. .|:...|:...::.||:..|..|| .|..||. ||.
Mosquito 1319 KLPLSK--------------------ANVIKNSEECSRRFQKSTSSFALGGIAGSVDLLARIADG 1363
Fly 1384 PL--------ICVNCLKCKSCSTTKVSKF-VGNLPMCTGCFKLRKKGNFCPICQRCYDDNDFDLK 1439
.: :|....:.|||::.::... |.:..:...|.|:|::
Mosquito 1364 TIPKASPTKSVCSKRSRRKSCASDRLEVMSVKSYGVIGSCGKIRQR------------------- 1409
Fly 1440 MMECGDCGQWVHSKCEGLSDEQYNLLSTLPESIEFICKKCARRNESSKIKAEEWRQAVMEEFKAS 1504
.|||: .:|:.|:..|:..|...|:.
Mosquito 1410 ------------------------RLSTM--------SRCSSRSAGSRHAAARMRRR-------- 1434
Fly 1505 LYSVLKLLSKSRQACALLKLSPRKKLRCTCGASSNQGKLQPKALQFSSGSDNGLGSDGESQNSDD 1569
:|:||....|.....::.. ..|..||..:.|.:.:|.
Mosquito 1435 ----------------------KKRLRSMSVAPGTTAEMVS-----GGGGGNGGAAGGAASSSG- 1471
Fly 1570 VYEFKDQQQQQQQRNANMNKPRVKSLPCSCQQHISHSQSFSLVDIKQKIAGNSYVSLAEFNYDMS 1634
:|:|..:
Mosquito 1472 ------------------------------------------LDLKLNV---------------- 1478
Fly 1635 QVIQQSNCDELDIAYKELLSEQFPWFQNETKACTDALEEDMFESCSGGNYEDLQDTGGVSASVYN 1699
|:| .|||.| :..| :..|| :|.|
Mosquito 1479 ---------EID-----RLSESF------SGMC--------------------RIVGG---TVNN 1500
Fly 1700 EHSTSQAESRSGVLDIPLEEVDDFGSCGIKMRLDTRMCLFCRKSGEGLSGEEARLLYCGHDCWVH 1764
| ..||.|.:|....|.||.....: ..:....||: || .
Mosquito 1501 E--AGQASSGAGRSVSPPEEATATNA---------------PAAATPTSGK-------GH----Q 1537
Fly 1765 TNCAMWSAEVFEEIDGSLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCA 1829
|..::...:..|.:..|......|.|.|. |..||
Mosquito 1538 TKRSVKKRKASEHVTDSPSTAGGANAPGG-------GGGGA------------------------ 1571
Fly 1830 FLTDKSMYCPAHAKNGNALKANGSPSVTYESNFEVSRPVYVELDRKRKKLIEPARVQFHIGSLEV 1894
|...||......|... .|:.||.:.......|
Mosquito 1572 ----------AALGNGGGAGGGGGTG-----------------KRRNKKTVPTQSPDDH------ 1603
Fly 1895 RQLGAIVPRFSDSYEAVVPINFLCSRLYWSSKEPWKIVEYTVRTTIQNSSSTLTALDVGRNYTVD 1959
|.|.|...| .||..:.|.| .
Mosquito 1604 -------------------------------KLPLKKRHY-----------LLTPGEKGNN---S 1623
Fly 1960 HTNPNSKEVQLGMAQIARWHTSLARSEFLENGGTDWSGEFPNPNSCVPPDENTEEEPQQQADLLP 2024
..|....||:.|.:. .|||
Mosquito 1624 DNNSGVDEVKTGSSG--------------GNGG-------------------------------- 1642
Fly 2025 PELKDAIFEDLPHELLDGISMLDIFLYDDKTDLFAISEQSKDGTQAMTSNQAQNQNQQAGGANSV 2089
|:. |:.| .|...|..:|.:::.
Mosquito 1643 -----------------GVG----------------------GSSA----TAAGSNVDSGNSSTS 1664
Fly 2090 SICDEDTRNSNTSLGNGWPASNPVEDAMLSAARNSSQVQMLKTLAWPKLDGNSAMATAIKRRKLS 2154
......:.::|:|........||. |..|.||:|:. .......:.|.:..|...|:|.|.
Mosquito 1665 GATGSGSGSANSSFIGSHTVLNPC--AFASGARSSAN----SAATGSSISGAATKAVTPKKRHLL 1723
Fly 2155 KNLAEGVFLT---LSSQQRNKKEMATVAGVSRRQSISETSVEGVATTSGSVRSKSFTWSAAKRYF 2216
|:...|...| |..|.::.....|: ::.....|....:||..|...|
Mosquito 1724 KSPEPGPVPTDTELQLQIKSSDSPLTI--------VNGGGASGTVGDAGSSPSDGHT-------- 1772
Fly 2217 EKSEGREEAAKMRIMQMDGVDDSITEFRIISGDGNLSTAQFSGQVKCDRCQCTYRNYDAFQRHLP 2281
.||:.| :||. :.|..:.:..|.:..|...: :..:..|....
Mosquito 1773 ---VGRKAA-------VDGA---------VGGSPSNAAGQANPPVAGSK-----KKTNRQQEGSS 1813
Fly 2282 SCSPTMSSNETESDVSGQ-GMTNNATQISAESLNELQKQLLANAGGLNYLQSATSFPQV-QSLGS 2344
..|.|:|.....:..||| |.|:. |:.|..:..:..:.|.| ||.||
Mosquito 1814 ISSSTVSRERQATGASGQPGTTSE------------------NSAGPQHRSTPPARPSVIQSSGS 1860
Fly 2345 LGQFGLQGLQQLQLQPQSLGSGFFLSQ--PNPATQANTDDLQIY---ANSLQSLAA--------N 2396
:.|.:....:..|. |.|.....|.||::. .:|:.||.| .
Mosquito 1861 -------------VHPAASSGAYSASSAGPPPGVFEPTVDLELVIPPPSSIPSLIAKVEMLDSPR 1912
Fly 2397 LGGGFTLAQPTVTAPAQPQLIAVSTNPDGTQQFIQIPQTMQATTTPTATYQTLQATNTDKKIMLP 2461
||| ..|.|.|. |:.::..|:...: ||...:...|.|.|. ::....
Mosquito 1913 LGG------KDVAAAAG----AIGSSSSGSSGNV-------ATKLESEELQVLTAA---QRKAAG 1957
Fly 2462 LTAAGKPLKTVATKAAQQAAVKQRQL-KSG-HQVKPIQAKLQPH----PQQHQQQQQTQVQQP-- 2518
|.|....|.|::|.:|....|.::.| |:| |.:...:.:.:|: |...:::::.....|
Mosquito 1958 LGAGSALLATISTASASSEKVLEKLLTKTGAHHLLMKKKRKKPNRTGFPTVKKKKKKLPDNDPLD 2022
Fly 2519 --ITVMGQNLLQPQL---LFQSSTQT-----QAPQIILPQAQPQNIISFVTGDGSQGQPLQYISI 2573
::|:. |:|:: ||.||..| :|.:..:.:.|.|: ..|.|:......:
Mosquito 2023 DGLSVLD---LKPEVGPDLFDSSNLTRHVPSEAEKTRMKERQQQH-------HPSTGKHAACDRV 2077
Fly 2574 PTAGEYKPQPQPTATPTFLTTAPGAGATYLQTDASGNLVLTTTPSNSGLQMLTAQSLQAQPQVIG 2638
|..|| .|..|:....|.| ...|.:::.:.|| |
Mosquito 2078 PKEGE--------PTDCFIERHTGVG-------------------RPRLSVVSLEKLQ------G 2109
Fly 2639 TLIQPQTIQLGGGADGNQPGSNQQPLILGGTGGGSSGLEFATTSPQVILATQPMYYGLETIVQNT 2703
.|..| ||||. :.|||.| ||... |.:::: |.
Mosquito 2110 KLPLP--------------------------GGGSR--DVATTPP----ATGGR--GRKSVI-NP 2139
Fly 2704 VMSSQQFVSTAMPGMLSQNASFSATTTQVFQASKIEPIVDLPAGYVVLNNTGDASSAGTFLNAAS 2768
:.:..|..:....|:..:..:.:|.|.......:.|....||...| |....|.......|
Mosquito 2140 LAAEHQLAAQRSRGLRDEPPAAAAGTVGRKGKKRQEAPKPLPETAV-----GKRQKASMDTEIRS 2199
Fly 2769 VLQQQTQDDTTTQILQNANFQFQSVPTSSGASTSMDYTSPVMVTAKIPPVTQIKRTNAQAKAAGI 2833
..::......:....|..|....|...|.||:...:..: :::|| .|..:.||.||.
Mosquito 2200 AKERNRSKSVSVASEQLPNIVRLSETLSKGAAAKENKEN-----SRLPP----GRPPSAAKRAGK 2255
Fly 2834 SGVGKVPPQPQ-----VVNKVLPTSIVTQQSQVQV---KNSNLKQSQVKGKAASGTGTTCGAPPS 2890
.........|| |:.:...:|:....|:|:. .:.:..:.:..||.||.:.|
Mosquito 2256 EPATSAETAPQDDAAGVIRRTRSSSVALDPSEVKKLHHHHHHDAEHESAGKGASQSST------- 2313
Fly 2891 IASKPLQKKTNMIRPIHKLEVKPKVMKPTPKVQNQNHSLLQQQQQQQPQLQQQIPAVVVNQVPKV 2955
|::..:..|..:| |::.:.| ...|.|::
Mosquito 2314 ----PVRPHSGGIAALH----------------NEDSTSL----DSMPLLKR------------- 2341
Fly 2956 TISQQRIPAQTQQQQLQQAQMIHIPQQQQPLQQQQVQVQPSMPIITLAEAPVVQSQFVMEPQALE 3020
:| .:.:.:.|..:.|::.|..:|.:|....:....|:
Mosquito 2342 ---------------------LH----SRSISRMQSVITPTVVIEPIATSPKTPGRPRGRPR--- 2378
Fly 3021 QQELANRVQHFSTSSSSSSSNCSLPTNVVNPMQQQAPSTTSSSTTRPTNRVLPMQQRQEPAPLSN 3085
:||..:::...:.||....|.:.: |.|..:.|..|: ....||...:|||:
Mosquito 2379 -----------TTSPITATETPNSPTATAGPGRGR-PRTALALTGNPS---AASMQRTPASPLSS 2428
Fly 3086 ECPVVSS----------------PTPP---KPVEQPIIHQMTSASVSKCYAQKSTLPSP----VY 3127
..|.|:: ..|| :|:| ::...::..|.||..|:| |.
Mosquito 2429 PSPTVAAAERTAGRKKQRLDGRKSVPPGLAEPIE-------SARLATRVTASKSVTPTPPVGTVI 2486
Fly 3128 EAELKVSSVLESIVPDVTMDAILEEQPVTESIYTEGLYEKNSPGESK-TEQLLLQQQQREQLNQQ 3191
...||... .|.|:.|...|:|..:. .|..||.:: :.:......:|..:...
Mosquito 2487 PTRLKRGK------SDETLRAQQLEKPTKKP-------RKELPGSAEPSPETAAHLSKRSAIASP 2538
Fly 3192 LVNNGYLLDKHTFQVEPMDTDVYREEDLEEEEDEDDDFSLKMATSACNDHEMSDSEEPAVKDKIS 3256
:|. .|:|.:|....:.....||.|.| .:...|.|:
Mosquito 2539 IVE----------PVDPEETAHVLQPASSTEELEHD--------------PLPPDEGPS------ 2573
Fly 3257 KILDNLTNDDCADSIATATTMEV---DASAGYQQMVEDVLATTAAQSAPTEEFEGALETAAVEAA 3318
|.|...|.....::..|.|: .|:||.: ....::..|.::: .||.:
Mosquito 2574 ---DFLRLTDTPSPTSSGETRELAMGGAAAGGR-------GAGTSKKLPRKKY----ITAGL--- 2621
Fly 3319 ATYINEMADAHVLDLKQLQNGVELELRRRKEEQRTVSQEQEQSKAAIVPTAAAPEPPQPIQEPKK 3383
.:|.: |::..|..:.:...|. ||:.:..|..
Mosquito 2622 ------FSDCY------------------KDDGTTGGEGRSGPKT----------PPETLLPPPA 2652
Fly 3384 MTGPHLLYEIQSEDGFTYKSSSITEIWEKVFEAVQVARRAHGLTPLPEGPLADMGGIQMIGLKTN 3448
.....| ||......|| .|:..:|..|
Mosquito 2653 YCERFL-------------------------------RRTVRDFQLP----YDLWWLQENG---- 2678
Fly 3449 ALKYLIEQLPGVEKCSKYTPKYHKRNGNVSTAANGAHGGNLGGSSASAALSVSGGDSHGLLDYGS 3513
:|||......: .|.|...||. |..
Mosquito 2679 -------KLPGRNSVPSW--NYRKIRTNVY--------------------------------YDV 2702
Fly 3514 DQDELEENAYDCARCEPYS-------NRSEYDMFSWLASRHRKQPIQVFVQPSDNELVPRRGTGS 3571
..:...:|...| .|:|.| ||..| .|.||.:
Mosquito 2703 KANPSTDNNTQC-NCKPDSGCQDDCLNRMVY-----------------------TECVPEQ---- 2739
Fly 3572 NLPMAMKYRTL---KETYKDYVGVFRSHIHGRGLYCTKDIEAGEMVIEYAGELIRSTLTDKRERY 3633
.|...:.|.. :..|...:..|.:...|.|:...:.|..|..::||.||::......:|.|.
Mosquito 2740 -CPCGDRCRNTCIQRHEYAPGLERFMTEEKGWGIRSRERISKGTFIMEYLGEVVTEREFKERMRT 2803
Fly 3634 YDSRGIGCYMFKIDDNLVVDATMRGNAARFINHCCEPNCYSKVVDILGHKHIIIFALRRIVQGEE 3698
........|...:|..||:|....|:..||:||.|.|||..:...:.|...:.:||:|.|...||
Mosquito 2804 MYLNDTHHYCLNLDGGLVIDGHRMGSDCRFVNHSCAPNCEMQKWSVNGLFRMALFAMRDIPPNEE 2868
Fly 3699 LTYDYKF----PFEDEKIPCSCGSKRCR 3722
|.|||.| |.|.: ||.|||::||
Mosquito 2869 LCYDYNFSLFNPSEGQ--PCRCGSEQCR 2894
| 
