DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MetRS-m and OVA1

DIOPT Version :9

Sequence 1:	NP_001262564.1	Gene:	MetRS-m / 41733	FlyBaseID:	FBgn0027083	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_191100.1	Gene:	OVA1 / 824706	AraportID:	AT3G55400	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	194/597 - (32%)
Similarity:	301/597 - (50%)	Gaps:	97/597 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VTTPIFYVNAAPHIGHLYSAVIADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGVPVAK 86
            :|||::||||.||:|..|:.:.||:..|:|||.  .:.|...|||||||.||..:|:.:|....:
plant    73 LTTPLYYVNAPPHMGSAYTTIAADSIARFQRLL--GKKVIFITGTDEHGEKIATSAAANGRNPPE 135

  Fly    87 YCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSDETFL 151
            :||.|||.||.:::...|..|.|||||:.:|:..|..|:..:...|.||.|.|.|.|||:.|.:.
plant   136 HCDLISQSYRTLWKDLDIAYDKFIRTTDPKHEAIVKEFYARVFANGDIYRADYEGLYCVNCEEYK 200

  Fly   152 TDSQLRLDEATGTRYSLESG----H--PVEWTEETNYMFRLSQFQ-------------------- 190
            .:.:|           ||:.    |  |....:|.||.|.||::|
plant   201 DEKEL-----------LENNCCPVHQMPCVARKEDNYFFALSKYQKPLEDILAQNPRFVQPSYRL 254

  Fly   191 DDVRHWVKTEARVRPAKFEKILLDTLSEPLPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVN 255
            ::|:.|:|:..|                   |.|:||.  .|.|.|||||||.||:|||.|||:.
plant   255 NEVQSWIKSGLR-------------------DFSISRA--LVDWGIPVPDDDKQTIYVWFDALLG 298

  Fly   256 YLSSVGYPDEK------FSAHWPPAQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVD 314
            |:|::...:::      .|..||.:..:||||||:||.:||.|.|::||||.|..::.|...|.|
plant   299 YISALTEDNKQQNLETAVSFGWPASLHLIGKDILRFHAVYWPAMLMSAGLELPKMVFGHGFLTKD 363

  Fly   315 GQKMSKSKHNVVDPLQAAQQYTMEGLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSR 379
            |.||.||..|.::|.:..|::..:.:|||.|||....:||:||..:..:|:|:.||:|:||||:|
plant   364 GMKMGKSLGNTLEPFELVQKFGPDAVRYFFLREVEFGNDGDYSEDRFIKIVNAHLANTIGNLLNR 428

  Fly   380 ASA---KSLNPGQIYPSP-SAEHLADLLRSLDVAKRLQDSLLQLSERCESHYECNHFHLVADTTM 440
            ...   |:.....:..|. :||.:.           |:|::.:|.|:..::||........:..:
plant   429 TLGLLKKNCESTLVVDSTVAAEGVP-----------LKDTVEKLVEKARTNYENLSLSSACEAVL 482

  Fly   441 AALHAANNFFESSKPWTL-KAGAPDGNQARLETIIAMTMDALRLSGIVLQPIIPQLANRLLDKLS 504
            ...:|.|.:.:...||.| |.|.....:|..:.:|  .::.:|:..:.|.|:.|.|:.|:..:|
plant   483 EIGNAGNTYMDQRAPWFLFKQGGVSAEEAAKDLVI--ILEVMRVIAVALSPVAPCLSLRIYSQL- 544

  Fly   505 VPTAQRGWNYLAESFATSPNSSNSPAGLGESRQLDGQTSALLFQRILEETSAKEVKEQKPQPAKR 569
                    .|..:.|.:...|.....|| :..|:..|.|. :|.|| |....||..|:||:..|:
plant   545 --------GYTEDQFNSITWSDTKWGGL-KGGQVMEQASP-VFARI-ELNPEKEEDEKKPKVGKK 598

  Fly   570 S-KSKKKERRET 580
            : |:|.|...:|
plant   599 TGKAKVKVVEQT 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MetRS-m	NP_001262564.1	MetRS_core	20..356	CDD:173907	134/365 (37%)
		PRK11893	21..553	CDD:237012	183/567 (32%)
		Anticodon_Ia_like	365..503	CDD:299868	34/142 (24%)
OVA1	NP_191100.1	PLN02224	1..616	CDD:177869	194/597 (32%)
		MetRS_core	70..405	CDD:173907	134/365 (37%)
		Anticodon_Ia_Met	414..544	CDD:153411	34/142 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	160	1.000	Domainoid score	I1273
eggNOG	1	0.900	-	-		E1_COG0143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6009
Inparanoid	1	1.050	290	1.000	Inparanoid score	I836
OMA	1	1.010	-	-		QHG54021
OrthoDB	1	1.010	-	-		D788159at2759
OrthoFinder	1	1.000	-	-		FOG0005001
OrthoInspector	1	1.000	-	-		oto4160
orthoMCL	1	0.900	-	-		OOG6_101119
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3534
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740