DRSC/TRiP Functional Genomics Resources

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Protein Alignment MetRS-m and TyrRS

DIOPT Version :9

Sequence 1:NP_001262564.1 Gene:MetRS-m / 41733 FlyBaseID:FBgn0027083 Length:582 Species:Drosophila melanogaster
Sequence 2:NP_648895.1 Gene:TyrRS / 39829 FlyBaseID:FBgn0027080 Length:525 Species:Drosophila melanogaster


Alignment Length:466 Identity:80/466 - (17%)
Similarity:145/466 - (31%) Gaps:165/466 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 PHIGHL---------------YSAVIADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGV 82
            ||:.:.               .:.:.||.|.....::.|...:.|.|...|.  .|:...|..||
  Fly    47 PHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWSLLELRTKYYEQ--VIKAMLSSIGV 109

  Fly    83 PVAK--------YCDDISQRYR-EVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIY--- 135
            |:.|        |  .:|:.|. :|::.:|:       .|:...|:|.|...:.:.     |   
  Fly   110 PLEKLKFVKGSDY--QLSKEYTLDVYKLSSV-------VTQHDAKKAGAEVVKQVE-----YPLL 160

  Fly   136 -SAAYSGWYCVSDETFLTDSQL-RLDEATGTRYSLESGHPVEWTEETNYM---------FRLSQF 189
             ...|.|...:.:|....|:|. .:|:.....:|.:....:.:.:..::|         .::|..
  Fly   161 SGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLPQLGYEKRIHFMNPMVPGLAGGKMSSS 225

  Fly   190 QDDVRHWVKTEARVRPAKFEKILLDTLSEP----------------------------------- 219
            ::|    .|.:....||..:|.|.....||                                   
  Fly   226 EED----SKIDLLDSPANVKKKLKKAFCEPGNIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHG 286

  Fly   220 -------LPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVN------------YLSSVGYPDE 265
                   ..|:......:::|     |.|...||..:::.|::            .||:..||  
  Fly   287 GDVTFLKYEDLEKYYAEDKLH-----PGDLKATVEKYINRLLDPIRKAFENPELQKLSAAAYP-- 344

  Fly   266 KFSAHWPPAQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPL- 329
                  |||:...|           .|....|..:.|.:|.:..     |:.:..::|...|.| 
  Fly   345 ------PPAKVKAG-----------AAPAAGADEDAPHRLDIRV-----GKVVEVARHPDADTLY 387

  Fly   330 -------QAAQQYTMEGLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSRASAKSLNP 387
                   :|..:..:.||..|:..|.                ||..|...|.||........|:.
  Fly   388 VLKIDLAEAQPRTIISGLVKFVTEEE----------------LNQRLVAVLCNLKPSKMRGILSE 436

  Fly   388 GQIYPSPSAEH 398
            |.:..:.:|:|
  Fly   437 GMVLCTSNADH 447

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MetRS-mNP_001262564.1 MetRS_core 20..356 CDD:173907 70/422 (17%)
PRK11893 21..553 CDD:237012 80/466 (17%)
Anticodon_Ia_like 365..503 CDD:299868 10/34 (29%)
TyrRSNP_648895.1 nt_trans 8..334 CDD:294020 49/311 (16%)
tyrS 12..332 CDD:272976 49/309 (16%)
tRNA_bind_EMAP-II_like 364..466 CDD:239198 21/105 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0143
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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