Protein Alignment MetRS-m and Mars1

DIOPT Version :10

• Sequence 1: NP_650348.1
• Gene: MetRS-m / 41733
• FlyBaseID: FBgn0027083
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_006241513.1
• Gene: Mars1 / 299851
• RGDID: 1305321
• Length: 910
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 143/629 - (22%)
• Similarity: 248/629 - (39%)
• Gaps: 142/629 - (22%)

  Fly    22 VTTPIFYVNAAPHIGHLYSAVI-ADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGVPVA 85
            :|:.:.|||..||:|::...|: ||...||.||| ....:.|| ||||:||..:..|...|:...
  Rat   270 ITSALPYVNNVPHLGNIIGCVLSADVFARYSRLR-QWNTLYLC-GTDEYGTATETKAMEEGLTPQ 332

  Fly    86 KYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSDETF 150
            :.||.....:.:::|..:|..|.|.|||.....:...:.::.|.|||.:.........|.....|
  Rat   333 EICDKYHAIHVDIYRWFNISFDTFGRTTTPLQTKITQDIFQRLLTRGFVLQDTVEQLRCEQCARF 397

  Fly   151 LTDSQLR-------LDEATGTR--------YSLE---------SGHPVEWTEETNYMF-RLSQFQ 190
            |.|..:.       .:||.|.:        .::|         ..|||  .:.:.::| .|.:.:
  Rat   398 LADRFVEGVCPFCGYEEARGDQCDKCGKLINAIELKRPQCKVCRSHPV--VKSSKHLFLDLPKLE 460

  Fly   191 DDVRHWVKTEARVRP-------AKFEKILLDTLSEPLPDVSVSRPSNRVHWAIPVPDD--DSQTV 246
            ..:..|:   .:..|       |:|  |:...|.:.|....::|.   :.|..|||.:  :.:..
  Rat   461 KRLEDWL---GKTMPGSDWTPNARF--IIRSWLRDGLKPRCITRD---LKWGTPVPLEGFEDKVF 517

  Fly   247 YVWLDALVNYLSSVGYPDEKFSAHWPPAQQV-----IGKDILKFHGIYWTAFLLAAGLEPPGQLY 306
            |||.||.:.|||......:::...|...:||     :.||.:.|||:.:          |...|.
  Rat   518 YVWFDATIGYLSITANYTDQWERWWKNPEQVDLYQFMAKDNVPFHGLVF----------PCSALG 572

  Fly   307 VHSHWTV-------------DGQKMSKSKH-NVVDPLQAAQQYTMEGLRYFLLREGVAHSDGNYS 357
            ...::|:             || |.|||:. .|...:........:..|::||.......|..:|
  Rat   573 AEDNYTLVKNLIATEYLNYEDG-KFSKSRGIGVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFS 636

  Fly   358 HVKAQRILNSELADTLGNLLSRASAKSLNPGQIYPSPSAEHLADLLRSLDVAKRLQDSLLQLSER 422
            ........||||.:.|||.::||       |..........:.:::.:.|            ..|
  Rat   637 WTDLLIKNNSELLNNLGNFINRA-------GMFVSKFFGGCVPEMVLTHD------------DRR 682

  Fly   423 CESH--YECNHFHLVAD---------TTMAALHAANNFFESSKPWTLKAGAPDGNQARLETIIAM 476
            ..:|  :|...:|.:.:         :.:......|.:.:.::||....| .:.::.|..|:..|
  Rat   683 LVAHVSWELQRYHQLLEKVRIRDALRSILTISRHGNQYIQVNEPWKRIKG-DEMDRQRAGTVTGM 746

  Fly   477 TMDALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATSPNSSNSPAG--LGESRQLD 539
            .::...|..::|||.:|.:::.:..:|.:|.|  ....||.||..:     .|||  :|
  Rat   747 AVNIAALLSVMLQPYMPTVSSTIQTQLQLPEA--ACRILATSFICT-----LPAGHRIG------ 798

  Fly   540 GQTSALLFQRI----------------LEETSAKEVKEQKPQPA 567
              |.:.|||::                |||:...:.| ..|:||
  Rat   799 --TVSPLFQKLENDQIENLRQRFGGGQLEESLELQAK-GSPKPA 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS-m	NP_650348.1	MetG	21..559	CDD:439913	139/619 (22%)
Mars1	XP_006241513.1	GST_N_5	1..74	CDD:436537
		GST_C_MetRS_N	77..179	CDD:198340
		PLN02610	258..>839	CDD:215329	141/627 (22%)
		MetRS_RNA	855..899	CDD:238475