Protein Alignment MetRS-m and Y105E8A.20

DIOPT Version :9

• Sequence 1: NP_001262564.1
• Gene: MetRS-m / 41733
• FlyBaseID: FBgn0027083
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001129797.1
• Gene: Y105E8A.20 / 173312
• WormBaseID: WBGene00013678
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 209/523 - (39%)
• Similarity: 320/523 - (61%)
• Gaps: 22/523 - (4%)

  Fly    18 SSHYVTTPIFYVNAAPHIGHLYSAVIADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGV 82
            ||.:||:||||.||.|||||.|:||:.|...|:.||::|....:...||||||:||.|||.....
 Worm    11 SSTFVTSPIFYANAEPHIGHAYTAVLCDVAHRWNRLKHPGAQAQFSIGTDEHGSKIFQAALAAKS 75

  Fly    83 PVAKYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSD 147
            ...::||.:|.::.::|....:...:|||||:..|..||.:||..:...|:||.:.|||:|.::|
 Worm    76 TPKQFCDRVSSKFSDLFTDLELSHTNFIRTTDPAHLEAVQHFWMKIQDNGYIYKSTYSGYYSITD 140

  Fly   148 ETFLTDSQL--RLDEATGTRYSLES-GHPVEWTEETNYMFRLSQFQDDVRHWVKTE-ARVRPAKF 208
            |.|:.:..:  ::.|....:.:|:| |.||||.||.|||||||:|::.|..|:..| ..|.|:|:
 Worm   141 ECFIPEEDVVKKIVEGGAEKLTLKSNGTPVEWIEEENYMFRLSEFREKVAEWINRENIVVHPSKY 205

  Fly   209 EKILLDTLSEPLPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVNYLSSVGYPDEKFSAHWPP 273
            :.:.|.:| |...|:|:||..:|:.|.||||:|.:||:|||||||||||:..|:|:.:  :.|||
 Worm   206 KSLALTSL-EMSEDLSISRSRSRLSWGIPVPNDPTQTIYVWLDALVNYLTVTGFPNAQ--SVWPP 267

  Fly   274 AQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPLQAAQQYTME 338
            ..|||||||.|||..||.|||:||||..|.::::|.||.:|..|||||..|||:|.:|..::|.|
 Worm   268 TCQVIGKDITKFHLYYWPAFLMAAGLSLPQKVFIHGHWLIDNVKMSKSLGNVVNPSEAITKFTAE 332

  Fly   339 GLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSRASAKSLNPGQIYPSPSAEHLADLL 403
            |||||||:.|....|.:::.....:.:||:|.:.:||||:|::.:.:|...:||....|.:...:
 Worm   333 GLRYFLLKHGNPSYDCSFNWNSCLQTINSDLVNNVGNLLNRSTVEKINKEGMYPKMEIEDIEAEI 397

  Fly   404 RSLDVAKRLQDSLLQLSERCESHYECNHFHLVADTTMAALHAANNFFESSKPWTLKAGAPDGNQA 468
            |  :.||:|.:.:.:..|.|...|:...:..:.:..|..:..||..|:||:||      .:.::.
 Worm   398 R--ENAKKLMEMVEESRENCVDLYDEMSYFKIIENLMLTMKEANRLFQSSQPW------KEIDEK 454

  Fly   469 RLETIIAMTMDALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATSPNSSNSPAGLG 533
            ||::::.:|.|.:|:..|:||||.|::|...|::|.||..:|       :...|...|.|...||
 Worm   455 RLKSLLFVTYDTIRVVTILLQPITPKMAEFCLNRLGVPKNER-------NLENSRFGSYSGGKLG 512

  Fly   534 ESR 536
            ..|
 Worm   513 AER 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS-m	NP_001262564.1	MetRS_core	20..356	CDD:173907	157/339 (46%)
		PRK11893	21..553	CDD:237012	207/520 (40%)
		Anticodon_Ia_like	365..503	CDD:299868	40/137 (29%)
Y105E8A.20	NP_001129797.1	PRK11893	12..519	CDD:237012	208/522 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	339	1.000	Domainoid score	I583
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6009
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1091
Isobase	1	0.950	-	0	Normalized mean entropy	S1506
OMA	1	1.010	-	-		QHG54021
OrthoDB	1	1.010	-	-		D334822at33208
OrthoFinder	1	1.000	-	-		FOG0005001
OrthoInspector	1	1.000	-	-		oto17435
orthoMCL	1	0.900	-	-		OOG6_101119
Panther	1	1.100	-	-	LDO	PTHR43326
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1450
SonicParanoid	1	1.000	-	-		X3534
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.960