Protein Alignment MetRS-m and MetRS

DIOPT Version :10

• Sequence 1: NP_650348.1
• Gene: MetRS-m / 41733
• FlyBaseID: FBgn0027083
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_061516386.1
• Gene: MetRS / 1278067
• VectorBaseID: AGAMI1_005510
• Length: 999
• Species: Anopheles gambiae
• Alignment Length: 645
• Identity: 153/645 - (23%)
• Similarity: 247/645 - (38%)
• Gaps: 167/645 - (25%)

  Fly    19 SHYVTTPIFYVNAAPHIGHLYSAVI-ADAHCRYQRLRYPEQDVRLC-------TGTDEHGTKIQQ 75
            ::.:|:.:.|||..||:|::...|: ||...||.         |||       .||||:||..:.
Mosquito   260 NNLITSALPYVNNVPHLGNIVGCVLSADIFARYS---------RLCGYNTLYIGGTDEYGTATET 315

  Fly    76 AASLHGVPVAKYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYS 140
            .|....:...:.||.....:..::|...|..|.|.|||.....|.|.:.::.|:..|:|.:.:..
Mosquito   316 KALAENMTPRQICDKYFDIHNSIYRWFGIGFDYFGRTTTAEQTRIVQDIFKELYASGYIETRSVE 380

  Fly   141 GWYCVSDETFLTD--------------SQLRLDEATG------------TRYSLESGHPVEWTEE 179
            ...|...:.:|.|              ...|.|:..|            .|..:.:..|| ..|.
Mosquito   381 QLLCQKCDRYLADRFVEGTCPHPGCGYEDARGDQCDGCGKLVNAVELLRPRCKMCNTSPV-IRES 444

  Fly   180 TNYMFRLSQFQDDVRHWV-KTE------ARVRPAKFEKILLDTLSEPLPDVSVSRPSNRVHWAIP 237
            :.:...|.:.:..:|.|| ::|      |||       |....|.|.|....::|.   :.|.||
Mosquito   445 SQFFLDLPKIEPTLREWVDRSEGGWTHNARV-------ITRAWLKEGLKSRCITRD---LKWGIP 499

  Fly   238 VPDD--DSQTVYVWLDALVNYLSSVGYPDEKFSAHWPP----------AQQVIGKDILKFHGIYW 290
            ||.:  :.:..|||.||.:.|:|......:::...|.|          ..|.:.||.:.||.:.:
Mosquito   500 VPLEGYEKKVFYVWFDAPIGYISITSRYCKEWKQWWQPDTANTGVKVDLYQFMAKDNVPFHSVMF 564

  Fly   291 TAFLLAA--GLEPPGQLYVHSHWTVDGQKMSKSK------HNVVDPLQAAQQYTMEGLRYFLLRE 347
            .|.|||.  |......:....:...:..|.|||:      ::..|....|..:     |::|
Mosquito   565 PASLLAVDKGYTLVSHVMATEYLNYEDGKFSKSRGIGVFGNDAQDTGIPADVW-----RFYL--- 621

  Fly   348 GVAHSDG-----NYSHVKAQRILNSELADTLGNLLSRA--SAKSLNPGQIYPSPSAEH----LAD 401
            |.|..:|     ::|.::|:.  ||||...|||..:||  ..:......|.|....|.    ||.
Mosquito   622 GAARPEGQDSSFSWSDLQARN--NSELLKNLGNFFNRALVFCEKFFDSTIPPMTLLEEDYTLLAL 684

  Fly   402 LLRSL-----DVAK-RLQDS---LLQLSERCESHYECNHFHLVADTTMAALHAANNFFESSKPWT 457
            :.|.|     .:.| |::|.   |||:|                       ...|...:|.:||
Mosquito   685 INRELKGYVNQMEKARMRDGIRHLLQIS-----------------------RYGNQLMQSEEPW- 725

  Fly   458 LKAGAPDGNQARLETIIAMTMDALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATS 522
            :|....|..:||..|:|.:..:...|...::.|.:|..|..:..:|:|    ||      .|..|
Mosquito   726 VKVKGTDDQKARAGTVIGLCCNFACLLATLIFPFMPTTARNMYSQLNV----RG------GFINS 780

  Fly   523 PN---SSNSPAG--LGESRQLDGQTSALLFQRI----LEETSAK-----EVKEQKPQPAK 568
            ..   .:..|.|  :|:        .|:||.:|    :||...|     :.|::.|.|.|
Mosquito   781 DKPLIRTLLPTGHRIGK--------PAVLFTKIEDARIEELKQKYGGVQQDKDKSPAPVK 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS-m	NP_650348.1	MetG	21..559	CDD:439913	149/632 (24%)
MetRS	XP_061516386.1	None