DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9631 and f9b

DIOPT Version :9

Sequence 1:	NP_650345.1	Gene:	CG9631 / 41729	FlyBaseID:	FBgn0027563	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	436	Identity:	107/436 - (24%)
Similarity:	163/436 - (37%)	Gaps:	90/436 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LKLGSALHVPQHNCERYFSYYKEDSGAYIGVFTAPRAGVNSLSWEVVFTAHGTGEANTVGSLIPY 79
            |::....||....| .:|....:..||........|..|:..|.|    ..|......:|.:|..
Zfish   125 LEMAKQCHVNNGGC-MHFCIVDKIYGAVCDCAEGYRLAVDGRSCE----PRGQYPCGRLGKIIAQ 184

  Fly    80 PNKERAFEKIHSGERGEVFVRFTDFGNELPKLVRAEFNGEVLCQNEEYDAPSSTMTRRQSM-STS 143
            ....||.|...:..:.:..               :..||      .||:...|:.|....| |||
Zfish   185 TLNSRALESTETVNQNQTI---------------SHING------TEYNTTESSPTDLSEMNSTS 228

  Fly   144 TPISQKSAPREIVRQRRPPPSTPSNDPNPFLPSIMPRIDSDFEECGVEGFSPLQIGGDLVTRGQY 208
            ||.:                |..:...:|.|.:|....::.:.          .:|||....|:.
Zfish   229 TPRN----------------SLQNVSSSPILTNINNTTNNKYR----------IVGGDEAIPGEI 267

  Fly   209 PWLAALYEGVGTATYKCVVSVISKRTVITAAHCIYGKSASQLWVYLGRHD--RNENPENGASLVS 271
            ||.....|.|....: |..|::|:..|||||||:.||..| .::.:|.||  :.|..|:...:..
Zfish   268 PWQVVFLEKVNKIVF-CGGSLLSEEWVITAAHCVEGKQGS-FFIRVGEHDVSKMEGTESDHGIEE 330

  Fly   272 VTSVLTPSAYEGNPVPDADVGLLVLTSPMVYTKYIRPLCLWGS-----NMGLPPNEGDTGAVAGW 331
            ..  :.|.......:.:.|:.||.|..|::...|..|:|| ||     |:   ....:...|:||
Zfish   331 YH--IHPRYNSQRSLYNHDIALLKLKKPVILFDYAVPICL-GSKDFTENL---LQSAENSLVSGW 389

  Fly   332 GYDRSA-------QKTRFPKTVSVRLVPRDQCLKEMKRAEDFITRRTVCAGNSE-SHGPCFGDSG 388
            |..|..       ||...|      .|.|.:|   ...:.|.|:|...|||.|. ....|.||||
Zfish   390 GRLRYGGIESNVLQKVELP------YVDRIKC---KGSSTDSISRFMFCAGYSTVRKDACQGDSG 445

  Fly   389 SALIVLRNNRWYVRGVVSLSPRHGEIC-DLSKYVIYCDVARHIDWV 433
            ........:.|::.|:||    .||.| ...||.||..:::::.|:
Zfish   446 GPHATRYKDTWFLTGIVS----WGEECAKEGKYGIYTRISKYMAWI 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..127	CDD:292649	16/100 (16%)
		Tryp_SPc	198..436	CDD:238113	74/252 (29%)
		Tryp_SPc	198..433	CDD:214473	73/250 (29%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342	8/36 (22%)
		Tryp_SPc	255..487	CDD:214473	73/262 (28%)
		Tryp_SPc	256..490	CDD:238113	74/253 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910