DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9631 and CG9649

DIOPT Version :9

Sequence 1:	NP_650345.1	Gene:	CG9631 / 41729	FlyBaseID:	FBgn0027563	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	153/503 - (30%)
Similarity:	228/503 - (45%)	Gaps:	75/503 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LTLLGL---CLNLKLGSALHVPQHNCERYFSYYKEDSGAYIGVFTAPRAGVNSLS-WEVVFTAHG 66
            |.|||.   .|.:...||.::|...|...|.|.:.|: .:||.........|:.: ..|..:..|
  Fly     4 LQLLGFLIAILQISYISAQNLPYIQCPMIFRYLEYDN-QFIGHLQLTLDSTNTENVVRVELSQRG 67

  Fly    67 TGEANTVGSLIPYPNKERAFEKIHSGERGEVFVRFTDFGNELPKLVRAEFNGEVLCQNEEYDAPS 131
            ....:|.|:|....:::....::.:.|.....:.|...| .:|||.:...||:|.|:...:.|||
  Fly    68 RNTPSTPGTLNFLEDEDSLRHRLTNNEPINYRIDFPTPG-VVPKLTKVTVNGKVACEAVPFGAPS 131

  Fly   132 STMTRRQSMSTSTPI-----SQKS------APR------------EIVRQRRP-----------P 162
            :.::..:::.||.|:     ||::      ||:            |.|::|||           .
  Fly   132 TRLSLSRTLRTSVPLAAIPPSQRTDHQWPQAPQTNYTVYEEEEEEEPVQRRRPQQRPSRPRPQQA 196

  Fly   163 PSTPSNDPNPFLP-------SIMPRIDSDFEECGVEGFSPLQIG-------------------GD 201
            ||.|...|.|.||       |..|.:...........|.|..||                   |.
  Fly   197 PSRPRLQPVPQLPQEPEFQTSARPSVHPSNTPAQASKFYPQTIGQLSGICGREKVIQTPFIHNGI 261

  Fly   202 LVTRGQYPWLAALYEGVG-TATYKCVVSVISKRTVITAAHCI-YGK---SASQLWVYLGRHDRNE 261
            .|.|||.||:|||:|.|| ...:.|..::||.||||:||||. :|.   ...:..|.|||:.. :
  Fly   262 EVERGQLPWMAALFEHVGRDYNFLCGGTLISARTVISAAHCFRFGSRNLPGERTIVSLGRNSL-D 325

  Fly   262 NPENGASLVSVTSVLTPSAYEGNPVPDADVGLLVLTSPMVYTKYIRPLCLWGSNMGLPPNEGDTG 326
            ...:||:| .|..:|....|..|...|||:.||.|::.:....||:|:|||..|..|....|...
  Fly   326 LFSSGATL-GVARLLIHEQYNPNVYTDADLALLQLSNHVDIGDYIKPICLWNENFLLELPSGHKS 389

  Fly   327 AVAGWGYDRSAQK-TRFPKTVSVRLVPRDQCLKEMKRAE-DFITRRTVCAGNSESHGPCFGDSGS 389
            .|||||.|....: ||..|.....::.:.:|...:.... .|||..|:||.|:::.|||.||||.
  Fly   390 YVAGWGEDEKGNRNTRLAKMTDTDIITQWECRGNLSEENAKFITSHTICASNAQASGPCSGDSGG 454

  Fly   390 ALIVLRNNRWYVRGVVSLSPRHGEICDLSKYVIYCDVARHIDWVRQNM 437
            .|::...:.|.:|||||...|....|:|:..|||.|||:||:|:..:|
  Fly   455 GLMLQEQDIWMLRGVVSAGQRMTNRCNLTLPVIYTDVAKHIEWLLSSM 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..127	CDD:292649	22/101 (22%)
		Tryp_SPc	198..436	CDD:238113	96/263 (37%)
		Tryp_SPc	198..433	CDD:214473	95/260 (37%)
CG9649	NP_650343.1	GD_N	29..124	CDD:292649	22/96 (23%)
		Tryp_SPc	257..498	CDD:238113	93/242 (38%)
		Tryp_SPc	259..497	CDD:214473	93/239 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	1	0.900	-	-		E33208_3BPFK
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I3868
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm14824
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.870