Protein Alignment CG9631 and KLKB1

DIOPT Version :10

• Sequence 1: NP_650345.1
• Gene: CG9631 / 41729
• FlyBaseID: FBgn0027563
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 118/526 - (22%)
• Similarity: 189/526 - (35%)
• Gaps: 187/526 - (35%)

  Fly     6 LTLLGLCLNLKL---GSALHVPQH---------------------------NCERYFSYY----K 36
            |:.:|.|....|   |..:::.||                           || .:|::|    |
Human   196 LSEIGNCRTTSLCDCGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNC-LFFTFYTNVWK 259

  Fly    37 EDSGAYIGVFTAPRAGVNSLSWEVVFTAHGTGEANTVGS--------LIPYPNKERAFEKIHSGE 93
            .:|...:.:.....:|..|.|         |.:.||:..        .:|.|    ...||:.|
Human   260 IESQRNVCLLKTSESGTPSSS---------TPQENTISGYSLLTCKRTLPEP----CHSKIYPG- 310

  Fly    94 RGEVFVRFTDFGNELPKLVRAEFN-----GEVLCQNEEYDAPSSTMTRRQSMSTSTPISQKSAPR 153
                    .|||.|       |.|     |..:||.     ..:.|.|.|.
Human   311 --------VDFGGE-------ELNVTFVKGVNVCQE-----TCTKMIRCQF-------------- 341

  Fly   154 EIVRQRRPPPSTPSNDPNPFLPSIMPRIDSDFEEC-----------------GVEGFSPLQ---- 197
                               |..|::|. |...|:|                 |.:|.|...
Human   342 -------------------FTYSLLPE-DCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLC 386

  Fly   198 ----------------IGGDLVTRGQYPWLAALYEGVGTATYKCVVSVISKRTVITAAHCIYGKS 246
                            :||...:.|::||..:|...:....:.|..|:|..:.|:|||||..|..
Human   387 NTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLP 451

  Fly   247 ASQLW-VYLGRHDRNENPENGASLVSVTSVLTPSAY---EGNPVPDADVGLLVLTSPMVYTKYIR 307
            ...:| :|.|..:.::..:: .....:..::....|   |||    .|:.|:.|.:|:.||::.:
Human   452 LQDVWRIYSGILNLSDITKD-TPFSQIKEIIIHQNYKVSEGN----HDIALIKLQAPLNYTEFQK 511

  Fly   308 PLCLWGSNMGLPPNEGDTGA------VAGWGYDR-SAQKTRFPKTVSVRLVPRDQCLKEMKRAED 365
            |:||        |::|||..      |.|||:.: ..:.....:.|::.||..::|   .||.:|
Human   512 PICL--------PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC---QKRYQD 565

  Fly   366 F-ITRRTVCAGNSE-SHGPCFGDSGSALIVLRNNRWYVRGVVSLSPRHGEICDLSKYV-IYCDVA 427
            : ||:|.||||..| ....|.||||..|:...|..|.:.|:.|    .||.|...:.. :|..||
Human   566 YKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITS----WGEGCARREQPGVYTKVA 626

  Fly   428 RHIDWV 433
            .::||:
Human   627 EYMDWI 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..132	CDD:464985	27/149 (18%)
		Tryp_SPc	198..436	CDD:238113	73/250 (29%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519	14/92 (15%)
		APPLE	303..386	CDD:128519	24/137 (18%)
		Tryp_SPc	402..632	CDD:238113	72/249 (29%)