Protein Alignment CG9631 and HPN

DIOPT Version :10

• Sequence 1: NP_650345.1
• Gene: CG9631 / 41729
• FlyBaseID: FBgn0027563
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 81/281 - (28%)
• Similarity: 125/281 - (44%)
• Gaps: 60/281 - (21%)

  Fly   186 EECGVEGFSPLQ--IGGDLVTRGQYPWLAAL-YEGVGTATYKCVVSVISKRTVITAAHCI--YGK 245
            ::||.... |:.  :||...:.|::||..:| |:|    .:.|..|::|...|:|||||.  ..:
Human   151 QDCGRRKL-PVDRIVGGRDTSLGRWPWQVSLRYDG----AHLCGGSLLSGDWVLTAAHCFPERNR 210

  Fly   246 SASQLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEGNPVP---------DADVGLLVLTSPMV 301
            ..|:..|:.|. ....:| :|..| .|.:|:    |.|..:|         ..|:.|:.|:||:.
Human   211 VLSRWRVFAGA-VAQASP-HGLQL-GVQAVV----YHGGYLPFRDPNSEENSNDIALVHLSSPLP 268

  Fly   302 YTKYIRPLCLWGSNMGLPPNEGDTGAVAGWG----YDRSA---QKTRFPKTVSVRLVPRDQCLKE 359
            .|:||:|:||..:...|.  :|....|.|||    |.:.|   |:.|.|      ::..|.|
Human   269 LTEYIQPVCLPAAGQALV--DGKICTVTGWGNTQYYGQQAGVLQEARVP------IISNDVC--- 322

  Fly   360 MKRAEDF----ITRRTVCAGNSESH-GPCFGDSGSALI----VLRNNRWYVRGVVSLSPRHGEIC 415
              ...||    |..:..|||..|.. ..|.||||...:    :.|..||.:.|:||    .|..|
Human   323 --NGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVS----WGTGC 381

  Fly   416 DLS-KYVIYCDVARHIDWVRQ 435
            .|: |..:|..|:...:|:.|
Human   382 ALAQKPGVYTKVSDFREWIFQ 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..132	CDD:464985
		Tryp_SPc	198..436	CDD:238113	78/267 (29%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	2/8 (25%)
		Tryp_SPc	163..400	CDD:238113	76/264 (29%)