Protein Alignment CG9631 and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_650345.1
• Gene: CG9631 / 41729
• FlyBaseID: FBgn0027563
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 105/476 - (22%)
• Similarity: 180/476 - (37%)
• Gaps: 135/476 - (28%)

  Fly     6 LTLLGLCLNLKLGSALHVPQHNCERYFSYYKEDSGAYIGVFTAPRAGVNSLSWEVVFTAHGTGEA 70
            |.:|.:|    :|..:|..::|.::.::||                  ::||    ||.
Human    29 LIVLAVC----IGLTVHYVRYNQKKTYNYY------------------STLS----FTT------ 61

  Fly    71 NTVGSLIPYPNKERAFEKIHSGERGEVFVRFTDFGNELPKLVRAEFNGEVLCQNEEYDAPSSTMT 135
                            :|:::....|....||:....|..:|:..|....|  .||: ..|..:.
Human    62 ----------------DKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPL--REEF-VKSQVIK 107

  Fly   136 RRQSM--------------STSTPISQKSAPREIVRQR-RPPPSTPSNDPNPFLPSIMPRIDSDF 185
            ..|..              ||..|.:.....:.::.:: :.....|..||:......:.:.::|.
Human   108 FSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDS 172

  Fly   186 ---EECGVE-----GFSPLQIGGDLVTRGQYPWLAAL-YEGVGTATYKCVVSVISKRTVITAAHC 241
               ..||..     |.|...:||..|..|::||.|:| ::|    :::|..::|:...:::||||
Human   173 YLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDG----SHRCGATLINATWLVSAAHC 233

  Fly   242 IYGKSASQLWVYLGRHDRNENPENGASLVSVT-----------SVLTPSAYEGNPVPDADVGLLV 295
            .               ...:||....:...||           .::....|: :|..|.|:.|..
Human   234 F---------------TTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYK-HPSHDYDISLAE 282

  Fly   296 LTSPMVYTKYIRPLCLWGSNMGLPPNEGDTGAVAGWG----------YDRSAQKTRFPKTVSVRL 350
            |:||:.||..:..:||..::....|  ||...|.|:|          :.|.||         |.|
Human   283 LSSPVPYTNAVHRVCLPDASYEFQP--GDVMFVTGFGALKNDGYSQNHLRQAQ---------VTL 336

  Fly   351 VPRDQCLKEMKRAEDFITRRTVCAGNSESH-GPCFGDSGSALIVL-RNNRWYVRGVVSLSPRHGE 413
            :....| .|.:...|.||.|.:|||:.|.. ..|.||||..|:.. ..:.||:.|:||    .|:
Human   337 IDATTC-NEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVS----WGD 396

  Fly   414 IC-DLSKYVIYCDVARHIDWV 433
            .| ..:|..:|..|....||:
Human   397 ECAKPNKPGVYTRVTALRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..132	CDD:464985	17/105 (16%)
		Tryp_SPc	198..436	CDD:238113	70/261 (27%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188	21/142 (15%)
		Tryp_SPc	192..420	CDD:238113	70/262 (27%)