Protein Alignment CG9631 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_650345.1
• Gene: CG9631 / 41729
• FlyBaseID: FBgn0027563
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 76/323 - (23%)
• Similarity: 128/323 - (39%)
• Gaps: 67/323 - (20%)

  Fly   116 FNGEVLCQNEEYDAPSSTMTRRQSMSTSTPISQKSAPREIVRQRRPPPSTPSNDPNPFLPSIMPR 180
            |.|.....::.| :||.......|...:....|..|.|:.:|:||..
Human    12 FVGSSHLYSDHY-SPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREG------------------ 57

  Fly   181 IDSDFEECGVEGFSPLQ--------IGGDLVTRGQYPWLAALYEGVG-TATYKCVVSVISKRTVI 236
             .:..|:||.   :||:        |||.....|.:||:.:|....| ...:.|..:::.:|.|:
Human    58 -GAHAEDCGT---APLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVL 118

  Fly   237 TAAHCIYGKSASQLWVYL-------GRHDRNENPENGASLVSVTSVLTPSAYEGNPVPDADVGLL 294
            |||||....|...:|..:       ||:...:..:..|.::....:|  .:|..      |:.|.
Human   119 TAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFIL--ESYVN------DIALF 175

  Fly   295 VLTSPMVYTKYIRPLCLWGSNMGLPPN-----EGDTGA-VAGWGYDR-SAQKTRFPKTVSVRLVP 352
            .|...:.|..||:|:|       ||.:     :|:|.. ::|||..: ....|...:...|..:.
Human   176 HLKKAVRYNDYIQPIC-------LPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYIS 233

  Fly   353 RDQCLKEMKRAEDFITRRTVCAGNSE-SHGPCFGDSGSALI--VLRNNRWYVRGVVSLSPRHG 412
            |:.|..| :.....|...:.|||:.: :...|.||||..|:  :....|::|.|:.|..  ||
Human   234 REMCNSE-RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYG--HG 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..132	CDD:464985	4/15 (27%)
		Tryp_SPc	198..436	CDD:238113	59/233 (25%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		4/21 (19%)
		Tryp_SPc	78..316	CDD:238113	59/234 (25%)