DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9631 and Sp212

DIOPT Version :9

Sequence 1:	NP_650345.1	Gene:	CG9631 / 41729	FlyBaseID:	FBgn0027563	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	150/521 - (28%)
Similarity:	237/521 - (45%)	Gaps:	97/521 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LTLLGLCLNLKLGSALHVPQHNCERYFSYYKEDSGAYIGVFTAP--RAGVNSLSWEVVFTAHGTG 68
            |.|:.:...:.|..|..||:::|..||.|..:......|..|.|  ..|.|.:  ::.|:..|..
  Fly     3 LELIVIVSLIALAGAQLVPENSCPDYFRYVNDAFQGVQGEITLPSLMRGRNRI--DIRFSQRGEQ 65

  Fly    69 EANTVGSLIPYPNKERAFEKIHSGERGEVFVRFTDFGNELPKLVRAEFNGEVLCQNEEYDAPSST 133
            :|:.||||||||: |.|..::....:..:.|| .:..|.||||.|..:|.::||...||..|:|.
  Fly    66 DASAVGSLIPYPD-ENAVRQLTGSAKFRIAVR-PNSSNGLPKLTRLSYNEQILCSASEYRPPNSF 128

  Fly   134 MTRRQSMSTS---------------------------------------------TPISQKS--- 150
            ..|...:..|                                             |.:|.:|
  Fly   129 FNRFYELDISGSLASFPSSVFNPFTRDGLDVNVQTVFYPTSSRGNDIWRGFTQPWTTVSNRSPAV 193

  Fly   151 -----APREIVRQR------------------RPPPSTPSNDPNPFLPSIM-------------P 179
                 .|.||...:                  .|.|:.|...|.|..|:::             |
  Fly   194 VTPAPTPTEIFWNQPVPSVPITFAPPVPTITSSPAPAPPPPPPLPTPPAVVTVPPATPPPQRFDP 258

  Fly   180 RIDSDFEECGVEG-FSPLQIGGDLVTRGQYPWLAALY-EGVGTATYKCVVSVISKRTVITAAHCI 242
            |.......||.|| .:|..:.|:...|||||||:|:| :.|....:||..|:||...||:||||:
  Fly   259 RSQISSVVCGREGSTTPFIVRGNEFPRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCV 323

  Fly   243 YGKSASQLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEGNPVPDADVGLLVLTSPMVYTKYIR 307
            :..:..::.|.|||:|.::..|:||.:.:|..:|....|......|||:.|:.:..|:.:...|.
  Fly   324 HRMTEDRVVVGLGRYDLDDYGEDGAEMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIA 388

  Fly   308 PLCLWGSNMGLPPNEGDTGAVAGWGYDRSAQKTRFPKTVSVRLVPRDQCLKEMKRAEDFITRRTV 372
            |:|:|  .:........||.:||||.|..:.:|::|:.|...:.....|....:..  .:|.|::
  Fly   389 PICMW--TVEASRTVSTTGFIAGWGRDEDSSRTQYPRVVEAEIASPTVCASTWRGT--MVTERSL 449

  Fly   373 CAGNSESHGPCFGDSGSALIVLRNNRWYVRGVVSLSPR-HGEICDLSKYVIYCDVARHIDWVRQN 436
            ||||.:..|||.||||..|:|.:.:||.:||:||...| ....|.|::||:|||:::||:|:.:|
  Fly   450 CAGNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISEN 514

  Fly   437 M 437
            :
  Fly   515 I 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9631	NP_650345.1	GD_N	26..127	CDD:292649	33/102 (32%)
		Tryp_SPc	198..436	CDD:238113	85/239 (36%)
		Tryp_SPc	198..433	CDD:214473	84/236 (36%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649	33/102 (32%)
		Tryp_SPc	277..514	CDD:238113	85/240 (35%)
		Tryp_SPc	277..511	CDD:214473	84/237 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	1	0.900	-	-		E33208_3BPFK
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I3868
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm14824
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970