DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9631 and PRSS21

DIOPT Version :10

Sequence 1:NP_650345.1 Gene:CG9631 / 41729 FlyBaseID:FBgn0027563 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_006790.1 Gene:PRSS21 / 10942 HGNCID:9485 Length:314 Species:Homo sapiens


Alignment Length:281 Identity:79/281 - (28%)
Similarity:124/281 - (44%) Gaps:59/281 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   188 CGVEGFSPLQIGGDLVTRGQYPWLAA--LYEGVGTATYKCVVSVISKRTVITAAHCI-------- 242
            ||....:...:||:....|::||..:  |::     ::.|.||::|.|..:|||||.        
Human    33 CGRRVITSRIVGGEDAELGRWPWQGSLRLWD-----SHVCGVSLLSHRWALTAAHCFETYSDLSD 92

  Fly   243 -------YGKSAS-----QLWVYLGRHDRNENPENGASLVSVTSVLTPSAYEGNPVPDADVGLLV 295
                   :|:..|     .|..|..|:             .|:::.....|.||  ...|:.|:.
Human    93 PSGWMVQFGQLTSMPSFWSLQAYYTRY-------------FVSNIYLSPRYLGN--SPYDIALVK 142

  Fly   296 LTSPMVYTKYIRPLCLWGSNMGLPPNEGDTGA-VAGWGYDRSAQKTRFPKT---VSVRLVPRDQC 356
            |::|:.|||:|:|:||..|....   |..|.. |.||||.:..:....|.|   |.|.::....|
Human   143 LSAPVTYTKHIQPICLQASTFEF---ENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMC 204

  Fly   357 ----LKEMKRAEDFITRRTVCAGNSE-SHGPCFGDSGSALIVLRNNRWYVRGVVSLSPRHGEICD 416
                ||...|.:.|  ...|||||:: ....||||||..|...:|..||..||||.....|.   
Human   205 NHLFLKYSFRKDIF--GDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGR--- 264

  Fly   417 LSKYVIYCDVARHIDWVRQNM 437
            .::..:|.:::.|.:|:::.|
Human   265 PNRPGVYTNISHHFEWIQKLM 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9631NP_650345.1 GD_N 26..132 CDD:464985
Tryp_SPc 198..436 CDD:238113 76/268 (28%)
PRSS21NP_006790.1 Tryp_SPc 42..283 CDD:238113 76/268 (28%)
Blue background indicates that the domain is not in the aligned region.

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