DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and AZU1

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001691.1	Gene:	AZU1 / 566	HGNCID:	913	Length:	251	Species:	Homo sapiens

Alignment Length:	270	Identity:	74/270 - (27%)
Similarity:	111/270 - (41%)	Gaps:	70/270 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 RASTTPL--IFQGKSLQRGQLPWLVAIFERRESNGPAFICGGTLISTSTVLSAAHCFRA--PGRD 327
            ||.::||  |..|:..:..|.|:|.:|    ::.|..| |||.||....|::||.||::  ||..
Human    18 RAGSSPLLDIVGGRKARPRQFPFLASI----QNQGRHF-CGGALIHARFVMTAASCFQSQNPGVS 77

  Fly   328 LPASRLAVSLG-----------RNTLAIHSDGEFRGVSQLIIHENFQFKQFTEADLALVRLDEPV 381
                  .|.||           |.|.:|.|           :.||....|....||.|::||...
Human    78 ------TVVLGAYDLRRRERQSRQTFSISS-----------MSENGYDPQQNLNDLMLLQLDREA 125

  Fly   382 RYTD--YIVPICLWSTSNRMDLPQGLKSYVAGWGPDETGTGNTEVSKVTDLNIVSEANCALELPH 444
            ..|.  .|:|:.|.:.:    :..|.:..|||||...:|...:...:..::.:..|..|
Human   126 NLTSSVTILPLPLQNAT----VEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC------ 180

  Fly   445 VLVQPSSLCAKKTG-----AGPCASDGGGPLMLREQDVWVLRGVISGGVINEKENTCELSKPSVF 504
               :|:::|   ||     .|.|..|||.||        |..| ::.||.:.....|... |..|
Human   181 ---RPNNVC---TGVLTRRGGICNGDGGTPL--------VCEG-LAHGVASFSLGPCGRG-PDFF 229

  Fly   505 TDVAKHIEWV 514
            |.||...:|:
Human   230 TRVALFRDWI 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	69/258 (27%)
		Tryp_SPc	277..514	CDD:214473	68/256 (27%)
AZU1	NP_001691.1	Tryp_SPc	27..240	CDD:238113	70/261 (27%)
AZU1	NP_001691.1	Possesses antibiotic activity. /evidence=ECO:0000269\|PubMed:8506327	46..70		11/24 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910