DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and modSP

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	471	Identity:	103/471 - (21%)
Similarity:	157/471 - (33%)	Gaps:	121/471 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 RVDFPIPTIPPKITSMQLNGVQLCSGGVYP-----------KPRTGITLRITWTPSYI------S 145
            :|..|:.|..|    ::|.|..|..|...|           .|.|..|:|.:....|:      |
  Fly   208 KVTTPVVTETP----LELLGCPLPLGDERPILTGDGSRVLTGPITRGTVRFSCKQGYVLEGEESS 268

  Fly   146 VFGVNPQPVPTRPRPAWQDESPQIDYRETRPSQPRLEDSGELFGRSNESL-----------PAFQ 199
            ....|.....|.|:        .:.|..|         :||..|.|.::|           ..|.
  Fly   269 YCAKNKWSTSTIPK--------CVKYCST---------AGEFDGYSTKALCTHNGQQVECRKPFH 316

  Fly   200 NPGWGTAPQQANPNRGITSQPEIP----------SPVPQRPTPNPSRSNAPQQAVRSPVDLVPQQ 254
            .||                 .|:.          ||:|:.........|..:|  |...|
  Fly   317 PPG-----------------TEVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQ--RCEQD----- 357

  Fly   255 NPSSNGIPCGRERASTTPLIFQGKSLQRGQLPWLVAIFERRESNGPAFICGGTLISTSTVLSAAH 319
                    ||:...........|.::....:||.|.::.........|.|||:|::...|::|||
  Fly   358 --------CGQLATPIKQFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAH 414

  Fly   320 CFRAPGRDLPASR-----LAVSLGRNTLAIHSDGEFRGVSQLIIHENFQFKQFTE---ADLALVR 376
            |....|..||.|.     :|....||......:.:.|.|..:.|...  :|..||   .||||:.
  Fly   415 CVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPG--YKGRTENYYQDLALLT 477

  Fly   377 LDEPVRYTDYIVPICLW--STSNRMDLPQGLKSYVAGWGPDETGTGNTEVSKVTDLNIVSEAN-- 437
            ||||...:..|.|||:.  |.:.:..:...::...|||..:..       .::..:..||::|
  Fly   478 LDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENK-------HELQFVPAVSKSNSV 535

  Fly   438 CALELPHVLVQPSSLCAKKTGAG-PCASDGGG----PLMLREQDVWVLRGVISGGVINEKENTCE 497
            |...|..  :|....|....|.. .|..|.||    .|.......|........|||:...|..:
  Fly   536 CRRNLRD--IQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQ 598

  Fly   498 LSKP-SVFTDVAKHIE 512
            .:.. :|.|:: :|.|
  Fly   599 CAHSLTVMTNI-QHFE 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649	8/27 (30%)
		Tryp_SPc	277..517	CDD:238113	65/254 (26%)
		Tryp_SPc	277..514	CDD:214473	65/254 (26%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056	7/40 (18%)
		Sushi	309..354	CDD:278512	9/63 (14%)
		Tryp_SPc	371..616	CDD:214473	65/255 (25%)
		Tryp_SPc	371..591	CDD:304450	59/230 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436920
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940