DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and Hayan

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001097020.1	Gene:	Hayan / 32831	FlyBaseID:	FBgn0030925	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	130/507 - (25%)
Similarity:	191/507 - (37%)	Gaps:	163/507 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 HPEANNQTLILQFSQQGYHDFEDYVGSISLVDDDEVTQENLR-QGLPIRYRVDFPIPTIPPKITS 112
            :|..||..|                  |.||:|      .|| ||:.|.     |...:|
  Fly   253 NPSPNNNNL------------------IHLVND------RLREQGMQIE-----PAREVP----- 283

  Fly   113 MQLNGVQLCSGGVYPKPRTGITLRITWTPSYISVFGVNPQPVPTR---PRPAWQDESPQIDYRET 174
                                :.|:.|.||:        |.|.||:   |...::......| ::|
  Fly   284 --------------------MVLQTTPTPT--------PAPTPTQLIDPFEPYRFRGQDRD-KDT 319

  Fly   175 RPSQPRLEDSGELFGRSNESLPAFQNPGWGTAPQQANPNRGITSQPEIPSPVPQRPT---PNPSR 236
            :|.:|..:.|..|                     .|:|      .|.|.:|...|||   |||||
  Fly   320 QPQEPWNDVSNNL---------------------DADP------APSIFNPAETRPTTPNPNPSR 357

  Fly   237 SNAPQQAVRSPVDLVPQQNPSSNGIPCGRERASTTPL---IFQGKSLQRGQLPWLVAIFERRESN 298
            .|.|:           ::.||.  ..|.:.|:...||   |..|:.:.||..|.:.|| ......
  Fly   358 VNLPE-----------KERPSV--AACEKIRSGGKPLTVHILDGERVDRGVYPHMAAI-AYNSFG 408

  Fly   299 GPAFICGGTLISTSTVLSAAHCFRAPGRDLPASRL-AVSLGR--------NTLAIHSDGEFRGVS 354
            ..||.|||:||::..||:||||..:........|| |:::..        |.:.:....::.|.|
  Fly   409 SAAFRCGGSLIASRFVLTAAHCVNSDDSTPSFVRLGALNIENPEPGYQDINVIDVQIHPDYSGSS 473

  Fly   355 QLIIHENFQFKQFTEADLALVRLDEPVRYTDYIVPICLWSTSNRMDLPQGLKSYVAGWGPDETGT 419
            :..             |:|:::|.|..:.:|.|.|.||:  ::|.|.|...|.:|||||  ....
  Fly   474 KYY-------------DIAILQLAEDAKESDVIRPACLY--TDRSDPPANYKYFVAGWG--VMNV 521

  Fly   420 GNTEVSKV-----TDLNIVSEANCAL-ELPHVL------VQPSSLCA--KKTGAGPCASDGGGPL 470
            .|..|||:     .||....|.|.:. |.|...      |..|.|||  |......|..|.||||
  Fly   522 TNRAVSKILLRAALDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGGPL 586

  Fly   471 MLREQDV---WVLRGVISGGVINEKENTCELSKPSVFTDVAKHIEWVRQKMW 519
            :|...||   :.:.||||.|.      .|....|.::|.|:..::::...:|
  Fly   587 ILEIDDVDGTYSIVGVISSGF------GCATKTPGLYTRVSSFLDYIEGIVW 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649	15/77 (19%)
		Tryp_SPc	277..517	CDD:238113	77/265 (29%)
		Tryp_SPc	277..514	CDD:214473	77/262 (29%)
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	384..627	CDD:214473	78/266 (29%)
		Tryp_SPc	385..630	CDD:238113	78/268 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437074
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940