DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31326 and F7

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_011535776.2	Gene:	F7 / 2155	HGNCID:	3544	Length:	495	Species:	Homo sapiens

Alignment Length:	291	Identity:	90/291 - (30%)
Similarity:	134/291 - (46%)	Gaps:	67/291 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 PCGR-----ERASTTP--LIFQGKSLQRGQLPWLVAIFERRESNGPAFICGGTLISTSTVLSAAH 319
            |||:     :|.::.|  .|..||...:|:.||.|.:.    .|| |.:||||||:|..|:||||
Human   223 PCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLL----VNG-AQLCGGTLINTIWVVSAAH 282

  Fly   320 CFR--APGRDLPASRLAVSLGRNTLAIH-SDGEFRGVSQLIIHENFQFKQFTEADLALVRLDEPV 381
            ||.  ...|:|    :|| ||.:.|:.| .|.:.|.|:|:||...: ....|..|:||:||.:||
Human   283 CFDKIKNWRNL----IAV-LGEHDLSEHDGDEQSRRVAQVIIPSTY-VPGTTNHDIALLRLHQPV 341

  Fly   382 RYTDYIVPICL-WSTSNRMDLPQGLKSYVAGWGPDETGTGNTEVSKVTDLNIVSEANCALEL--- 442
            ..||::||:|| ..|.:...|.....|.|:|||                 .::.....||||
Human   342 VLTDHVVPLCLPERTFSERTLAFVRFSLVSGWG-----------------QLLDRGATALELMVL 389

  Fly   443 --PHVLVQPSSLCAKKTGAGP------------------CASDGGGPLMLREQDVWVLRGVISGG 487
              |.::.|.....::|.|..|                  |..|.|||.....:..|.|.|::|.|
Human   390 NVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG 454

  Fly   488 VINEKENTCELSKPSVFTDVAKHIEWVRQKM 518
                 :....:....|:|.|:::|||:::.|
Human   455 -----QGCATVGHFGVYTRVSQYIEWLQKLM 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	83/266 (31%)
		Tryp_SPc	277..514	CDD:214473	82/263 (31%)
F7	XP_011535776.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910