DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and AgaP_AGAP004566

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_313869.5	Gene:	AgaP_AGAP004566 / 1274708	VectorBaseID:	AGAP004566	Length:	327	Species:	Anopheles gambiae

Alignment Length:	372	Identity:	95/372 - (25%)
Similarity:	144/372 - (38%)	Gaps:	105/372 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 SGELF-------GRSNESLPAFQNPGWGTAPQQANP-------NRGITSQPEIPSPVPQRPTPNP 234
            :|.||       ||..|...|.:.|..|.. ::.||       ..|.||     :|.|:..||
Mosquito     9 AGLLFLSDLTTGGRIPEDRQALEIPAQGQT-EKNNPFIEWLAGLIGSTS-----TPAPENLTP-- 65

  Fly   235 SRSNAPQQAVRSPVDLVPQQNPSSNGIPCGRERASTTPLIFQGKSLQRGQLPWLVAIFERRESNG 299
                             |...|...   |||....|.  |..|:..|..|.||:..:    :.:|
Mosquito    66 -----------------PDSCPMCK---CGRTNRLTR--IVGGQETQVNQYPWMAML----QYSG 104

  Fly   300 PAFICGGTLISTSTVLSAAHCFRAPGRDLPASRLAVSLGRNTLAIHSDG--EFRGVSQLIIHENF 362
             .|.|||:|||...||:||||.....|    ::::|.|..:.....|:.  ....|.::|.|..:
Mosquito   105 -TFYCGGSLISDRHVLTAAHCVHGFNR----NKISVVLMEHDRVSTSESMTMVSKVLRVIEHNGY 164

  Fly   363 QFKQFTEADLALVRLDEPVRYTDYIVPICLWSTSNRMDLPQGLKSYVAGWG-PDETGTGNTEVSK 426
            ....: .:|:|::||...:...|.:.|:||.:.....   .|....|.||| ..|.|..:|.:.:
Mosquito   165 NSNNY-NSDIAILRLATVMTIEDKLRPVCLPTPKKPF---TGYDGIVTGWGATSENGAISTNLQE 225

  Fly   427 VTDLNIVSEANCALELPHVLVQPSSLCAKKTGAG-------------------PCASDGGGPLML 472
            || :.|:|.|:|                :|||.|                   .|..|.||||.:
Mosquito   226 VT-VPIMSNADC----------------RKTGYGASRITDNMLCAGYDEGKKDSCQGDSGGPLHV 273

  Fly   473 REQ----DVWVLRGVISGGVINEKENTCELSKPSVFTDVAKHIEWVR 515
            .:|    :|..:.|::|.|     |...:.:.|.|:|.|.:...|:|
Mosquito   274 IKQNSTDNVHQIAGIVSWG-----EGCAKPNYPGVYTRVNRFGTWIR 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	70/265 (26%)
		Tryp_SPc	277..514	CDD:214473	68/262 (26%)
AgaP_AGAP004566	XP_313869.5	Tryp_SPc	82..314	CDD:214473	69/268 (26%)
AgaP_AGAP004566	XP_313869.5	Tryp_SPc	83..317	CDD:238113	71/268 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910