DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31326 and AgaP_AGAP013487

DIOPT Version :9

Sequence 1:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_003436426.1	Gene:	AgaP_AGAP013487 / 11176153	VectorBaseID:	AGAP013487	Length:	308	Species:	Anopheles gambiae

Alignment Length:	290	Identity:	91/290 - (31%)
Similarity:	142/290 - (48%)	Gaps:	42/290 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 QNPSSNGIP----CGRERASTTPLIFQGKSLQRGQLPWLVAIFERRESNGP-AFICGGTLISTST 313
            ||.||  :|    ||.:....   :..|:|.|..:.|| .|:.|.::.:|. .|.|||:||:...
Mosquito    37 QNTSS--LPESPHCGIQLGDR---VLSGQSTQIDEFPW-TALIEFQKPDGSFGFHCGGSLINDRY 95

  Fly   314 VLSAAHCFRAPGRDLPASRLAVSLGRNTLAIHSD--GEF-------RGVSQLIIHENFQFKQFTE 369
            :::||||.::..||....|  |.||...|...:|  .||       ..:.|:::|..:..|..:.
Mosquito    96 IVTAAHCIKSIPRDWKVQR--VRLGEWDLTSANDCQNEFCSDAPIDLDIEQIVVHTGYDTKDKSN 158

  Fly   370 A-DLALVRLDEPVRYTDYIVPICL-WSTSNRMDLPQGLKSYVAGWGPDETGTGNTEVSKVTDLNI 432
            | |:||:|...||.|:..:.|||| .|:|.|.....||.||..||....:.|.:.:..|| ::.|
Mosquito   159 ANDIALIRFTRPVNYSQTVRPICLPLSSSLRNRSHDGLISYEVGWRKTNSATASEKKLKV-EVEI 222

  Fly   433 VSEANCA--LELPHVLVQPSSLCA-----KKTGAGPCASDGGGPLMLREQDVWVLRGVISGGVIN 490
            .|...||  .|...:|::.:.:||     |.|    |:.:.|||||.:....|.|.||.|.|
Mosquito   223 KSLQECAPIYERNGILLKQTHMCAGGVRSKDT----CSGNSGGPLMRQMTGSWYLIGVNSFG--- 280

  Fly   491 EKENTC-ELSKPSVFTDVAKHIEWVRQKMW 519
              ...| ....|.|:|:||::::|::..::
Mosquito   281 --PRKCGTFGVPDVYTNVAEYVDWIKDNIY 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	84/259 (32%)
		Tryp_SPc	277..514	CDD:214473	83/256 (32%)
AgaP_AGAP013487	XP_003436426.1	Tryp_SPc	55..303	CDD:214473	83/263 (32%)
AgaP_AGAP013487	XP_003436426.1	Tryp_SPc	59..306	CDD:238113	84/259 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910