DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9649 and CG5246

DIOPT Version :9

Sequence 1:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	67/248 - (27%)
Similarity:	118/248 - (47%)	Gaps:	32/248 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 GIEVERGQLPWMAALF----EHVGRDYNFLCGGTLISARTVISAAHCFRFGSRNLPGERTIVSLG 320
            |::...|..|:..::.    |||       |||::|:.:.:::||||..:..:.|    .||:
  Fly    45 GVDSPTGFAPYQVSIMNTFGEHV-------CGGSIIAPQWILTAAHCMEWPIQYL----KIVT-- 96

  Fly   321 RNSLDLFSSGATLGVARLLIHEQYNPNVYTDADLALLQLSNHVDIGDYIKPICLWNENFLLELPS 385
             .::|....||...|....||..::...|.: |:||:..:..:...|..:||.|.::..|.::
  Fly    97 -GTVDYTRPGAEYLVDGSKIHCSHDKPAYHN-DIALIHTAKPIVYDDLTQPIKLASKGSLPKV-- 157

  Fly   386 GHKSYVAGWGEDEK-GNRNTRLAKMTDTDIITQWECRGNLSEENAKFITSHTICASNAQASGPCS 449
            |.|..:.|||..:. |..:|:|.|: |.:.|....|:..:  .||.:::...:|....:..|.|.
  Fly   158 GDKLTLTGWGSTKTWGRYSTQLQKI-DLNYIDHDNCQSRV--RNANWLSEGHVCTFTQEGEGSCH 219

  Fly   450 GDSGGGLMLQEQDIWMLRGVVSAGQRMTNRCNLTLPVIYTDVAKHIEWLLSSM 502
            |||||.|:...|   .|.|||:.|:    .|.:..|.::..||.:.:|:...|
  Fly   220 GDSGGPLVDANQ---TLVGVVNWGE----ACAIGYPDVFGSVAYYHDWIEQMM 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	65/242 (27%)
		Tryp_SPc	259..497	CDD:214473	65/241 (27%)
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	65/242 (27%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	66/244 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436928
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940