DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9649 and CG31326

DIOPT Version :9

Sequence 1:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	203/550 - (36%)
Similarity:	291/550 - (52%)	Gaps:	86/550 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QLLGFLIAILQISYISAQNLPYIQCPMIFRYLEYDNQFIGHLQLTLDSTNTENVVRVELSQRG-R 68
            ||:..|:....|:.:..| ||...|...|:|..|..|:||.:::.....|.:.:: ::.||:| .
  Fly     5 QLVTVLLLASLINLVLGQ-LPRNGCSGRFQYQGYQGQYIGLVEVRHPEANNQTLI-LQFSQQGYH 67

  Fly    69 NTPSTPGTLNFLEDEDSLRHRLTNNEPINYRIDFPTPGVVPKLTKVTVNGKVACEAVPFGAPSTR 133
            :.....|:::.::|::..:..|....||.||:|||.|.:.||:|.:.:||...|....:..|.|.
  Fly    68 DFEDYVGSISLVDDDEVTQENLRQGLPIRYRVDFPIPTIPPKITSMQLNGVQLCSGGVYPKPRTG 132

  Fly   134 LSLSRTLRTS-VPLAAIPPS---QRTDHQW-PQAPQTNYTVYEEEEEEEPVQRRRPQQRPSRPR- 192
            ::|..|...| :.:..:.|.   .|....| .::||.:|.                :.|||:||
  Fly   133 ITLRITWTPSYISVFGVNPQPVPTRPRPAWQDESPQIDYR----------------ETRPSQPRL 181

  Fly   193 -------------------------PQQA------PSRPRL-QPVPQLPQEPEFQTSARPSVHP- 224
                                     ||||      .|:|.: .||||           ||:.:|
  Fly   182 EDSGELFGRSNESLPAFQNPGWGTAPQQANPNRGITSQPEIPSPVPQ-----------RPTPNPS 235

  Fly   225 -SNTPAQASK----FYPQTIGQLSGI-CGREKVIQTPFIHNGIEVERGQLPWMAALFEHVGRDYN 283
             ||.|.||.:    ..||.....:|| ||||:...||.|..|..::||||||:.|:||.  |:.|
  Fly   236 RSNAPQQAVRSPVDLVPQQNPSSNGIPCGRERASTTPLIFQGKSLQRGQLPWLVAIFER--RESN 298

  Fly   284 ---FLCGGTLISARTVISAAHCFRFGSRNLPGERTIVSLGRNSLDLFSSGATLGVARLLIHEQYN 345
               |:|||||||..||:|||||||...|:||..|..||||||:|.:.|.|...||::|:|||.:.
  Fly   299 GPAFICGGTLISTSTVLSAAHCFRAPGRDLPASRLAVSLGRNTLAIHSDGEFRGVSQLIIHENFQ 363

  Fly   346 PNVYTDADLALLQLSNHVDIGDYIKPICLWNENFLLELPSGHKSYVAGWGEDEKGNRNTRLAKMT 410
            ...:|:|||||::|...|...|||.|||||:.:..::||.|.||||||||.||.|..||.::|:|
  Fly   364 FKQFTEADLALVRLDEPVRYTDYIVPICLWSTSNRMDLPQGLKSYVAGWGPDETGTGNTEVSKVT 428

  Fly   411 DTDIITQWECRGNLSEENAKFITSHTICASNAQASGPCSGDSGGGLMLQEQDIWMLRGVVSAG-- 473
            |.:|:::..|...|..   ..:...::||....| |||:.|.||.|||:|||:|:||||:|.|
  Fly   429 DLNIVSEANCALELPH---VLVQPSSLCAKKTGA-GPCASDGGGPLMLREQDVWVLRGVISGGVI 489

  Fly   474 QRMTNRCNLTLPVIYTDVAKHIEWLLSSMW 503
            ....|.|.|:.|.::|||||||||:...||
  Fly   490 NEKENTCELSKPSVFTDVAKHIEWVRQKMW 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9649	NP_650343.1	GD_N	29..124	CDD:292649	28/95 (29%)
		Tryp_SPc	257..498	CDD:238113	121/245 (49%)
		Tryp_SPc	259..497	CDD:214473	119/242 (49%)
CG31326	NP_650344.2	GD_N	26..126	CDD:292649	28/100 (28%)
		Tryp_SPc	277..517	CDD:238113	121/245 (49%)
		Tryp_SPc	277..514	CDD:214473	120/242 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471085
Domainoid	1	1.000	145	1.000	Domainoid score	I9368
eggNOG	1	0.900	-	-		E33208_3BPFK
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	186	1.000	Inparanoid score	I6368
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	1	1.000	-	-		FOG0001808
OrthoInspector	1	1.000	-	-		mtm9620
orthoMCL	1	0.900	-	-		OOG6_124240
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X174
	11	10.800