DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9649 and Prss48

DIOPT Version :9

Sequence 1:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001001650.1	Gene:	Prss48 / 368202	MGIID:	2685865	Length:	312	Species:	Mus musculus

Alignment Length:	271	Identity:	85/271 - (31%)
Similarity:	131/271 - (48%)	Gaps:	40/271 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 LSGICGREKVIQTPFIHNGIEVERGQLPWMAAL-FEHVGRDYNFLCGGTLISARTVISAAHCFRF 305
            |..:|||.  :.|..|..|.:...|:.||..:| |     ||...|||:|||...|::||||.:
Mouse    27 LQSVCGRP--VHTGRIVGGQDAALGRWPWQVSLRF-----DYTHSCGGSLISDHWVLTAAHCIK- 83

  Fly   306 GSRNLPGERTIVS------LGRNSLDLFSSGATLGVARLLIHEQYNPNVYTDADLALLQLSNHVD 364
                    :|..|      ||....:..|:|....|:|:.|.:::.   :|:||:|||:||:.|.
Mouse    84 --------KTWYSFLYSVWLGSIDREYSSTGKEYYVSRIAIPDKHR---HTEADIALLKLSSRVT 137

  Fly   365 IGDYIKPICLWNENFLLELPSGHKSYVAGWGEDEKGNRNTRLAKMTDTDIITQWECR------GN 423
            ....|.||||.|.:..|.:|:  ..:|.|||::::|:..:.|.:: :..:|:...|.      |.
Mouse   138 FSSVILPICLPNISKQLTVPA--SCWVTGWGQNQEGHYPSTLQEL-EVPVISSEACEQLYNPIGV 199

  Fly   424 LSEENAKFITSHTICASNAQA-SGPCSGDSGGGLMLQEQDIWMLRGVVSAGQRMTNRCNLTLPVI 487
            ...:..:.|.....||...|: ...|.|||||.|......:|.|.||||.|.    .|...||.:
Mouse   200 FLPDLERVIKEDMFCAGERQSRKDSCKGDSGGPLSCHIDGVWRLMGVVSWGL----ECGKDLPGV 260

  Fly   488 YTDVAKHIEWL 498
            ||:|..:.:|:
Mouse   261 YTNVTYYQKWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	79/254 (31%)
		Tryp_SPc	259..497	CDD:214473	78/251 (31%)
Prss48	NP_001001650.1	Tryp_SPc	39..271	CDD:214473	79/255 (31%)
Prss48	NP_001001650.1	Tryp_SPc	40..274	CDD:238113	80/256 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12259
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860