DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9649 and gd

DIOPT Version :9

Sequence 1:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001259479.1	Gene:	gd / 32159	FlyBaseID:	FBgn0000808	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	149/567 - (26%)
Similarity:	248/567 - (43%)	Gaps:	113/567 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QLQLLGFLIAILQ-ISYISAQNLPYIQCPMIFRYLEYDNQFIGHLQLTLDSTNTENVVRVELSQR 66
            :|.|...||..:: ::...||.:|...||.:|:|....:::.|.:.:.....:....:||.||.|
  Fly     2 RLHLAAILILCIEHVTKAVAQGMPISPCPKVFQYRFDGSEWFGLMAVRSPDGHQPLHIRVTLSMR 66

  Fly    67 GRNTPSTPGTLNFLEDEDSL-RHRLTNNEPINYRIDFPTPGVVPKLTKVTVNGKVACEAVPFGAP 130
            |:.|..|.   |:|.:.:.| |.:.|:|.|:.|:|.||.....|||..::.|..|.|    ||:.
  Fly    67 GKPTTYTQ---NYLGEIELLTRGKFTHNAPVLYKIRFPKHHFPPKLLLMSANNHVIC----FGSG 124

  Fly   131 STRLSLSRTLRTSVPLAAIPPSQRTDHQWPQAPQTNYTVYEEEEEEEPVQRRRPQQRPSRPRPQQ 195
            ...:.:::.....:...:..|.:::.           .:.:.||||.    |:...:|
  Fly   125 EHSIFMTQIQLEHIRKLSFIPDKKSS-----------LLLDPEEEEV----RKTDDKP------- 167

  Fly   196 APSRPRLQ----PVPQLPQE--------PEFQTSAR-PSVH-----PSNTPAQASKFYPQTIGQL 242
             ||.|.:|    |..|.|:|        .:|..|.| .|:|     |.::....|..:...
  Fly   168 -PSTPHIQFKKKPFAQAPKEICGRIDRDLDFHLSQRTESLHVAIGEPKSSDGITSPVFVDD---- 227

  Fly   243 SGICGREKVIQTPFIH----NGIE---------VERGQLPWMAALFEHVGRDYNFLCGGTLISAR 294
                ..:.|::..|:.    ..||         :.||..||:||::.:.....:|.|||:|:|||
  Fly   228 ----DEDDVLEHQFVDESEAEAIESDSADSLPSITRGSWPWLAAIYVNNLTSLDFQCGGSLVSAR 288

  Fly   295 TVISAAHCFRFGSRNLPGERTIVSLGRNSLDLFSSGATLG--VARLLIHEQYNPNVYT-DADLAL 356
            .|||:||||:..::.......:|.|||::|..::...:|.  |..:.||..:|..:.: |||:|:
  Fly   289 VVISSAHCFKLFNKRYTSNEVLVFLGRHNLKNWNEEGSLAAPVDGIYIHPDFNSQLSSYDADIAV 353

  Fly   357 LQLSNHVDIGDYIKPICLWNENFLLELPSGHKSYVAGWG-------EDEK------GNRNTRLA- 407
            :.|.:.|....:|:|.|||:.:...|...|.:..|.||.       .|:|      |.::|..:
  Fly   354 IILKDEVRFNTFIRPACLWSGSSKTEYIVGERGIVIGWSFDRTNRTRDQKLSSELPGKKSTDASA 418

  Fly   408 -KMTDTDIITQWECRGNLSEENAKF---ITSHTICAS------NAQASGPC--SGDSGGGLMLQE 460
             |:....|:...||    ...||.|   .::.|.||.      :...||..  :|.||.||.::.
  Fly   419 PKVVKAPIVGNAEC----FRANAHFRSLSSNRTFCAGIQAEERDTHQSGASIYTGISGAGLFIRR 479

  Fly   461 QDIWMLRGVVSA---------GQRMTNRCNLTLPVIYTDVAKHIEWL 498
            .:.|||||.|||         .:.....|.....:||.||||.::|:
  Fly   480 NNRWMLRGTVSAALPAVETPDAESSHKLCCKNQYIIYADVAKFLDWI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9649	NP_650343.1	GD_N	29..124	CDD:292649	30/95 (32%)
		Tryp_SPc	257..498	CDD:238113	85/291 (29%)
		Tryp_SPc	259..497	CDD:214473	85/284 (30%)
gd	NP_001259479.1	GD_N	27..124	CDD:292649	32/103 (31%)
		Tryp_SPc	257..526	CDD:238113	83/272 (31%)
		Tryp_SPc	258..526	CDD:214473	83/271 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BPFK
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I3868
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26048
OrthoDB	1	1.010	-	-		D294086at33208
OrthoFinder	1	1.000	-	-		FOG0001808
OrthoInspector	1	1.000	-	-		mtm9577
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.880